Prion strains associated with iatrogenic CJD in French and UK human growth hormone recipients

Autor: Jean-Yves Douet, Alvina Huor, Hervé Cassard, Séverine Lugan, Naïma Aron, Chloé Mesic, Didier Vilette, Tomás Barrio, Nathalie Streichenberger, Armand Perret-Liaudet, Marie-Bernadette Delisle, Patrice Péran, Jean-Philippe Deslys, Emmanuel Comoy, Jean-Luc Vilotte, Katayoun Goudarzi, Vincent Béringue, Marcelo A. Barria, Diane L. Ritchie, James W. Ironside, Olivier Andréoletti

Publikováno v: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)

Abstract Treatment with human pituitary-derived growth hormone (hGH) was responsible for a significant proportion of iatrogenic Creutzfeldt–Jakob disease (iCJD) cases. France and the UK experienced the largest case numbers of hGH-iCJD, with 122 and

Externí odkaz: https://doaj.org/article/38331de11f744c59b42002fabad71f84

Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay.

Autor: Etienne Levavasseur, Anne-Gaëlle Biacabe, Emmanuel Comoy, Audrey Culeux, Katarina Grznarova, Nicolas Privat, Steve Simoneau, Benoit Flan, Véronique Sazdovitch, Danielle Seilhean, Thierry Baron, Stéphane Haïk

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0172428 (2017)

The transmission of classical bovine spongiform encephalopathy (C-BSE) through contaminated meat product consumption is responsible for variant Creutzfeldt-Jakob disease (vCJD) in humans. More recent and atypical forms of BSE (L-BSE and H-BSE) have b

Externí odkaz: https://doaj.org/article/92d7bd606b774c419f36a16bb1c2168f

Transgenic mouse models expressing human and macaque prion protein exhibit similar prion susceptibility on a strain-dependent manner

Autor: Emmanuel Comoy, Jean-Philippe Deslys, José Luis Pitarch, Patricia Aguilar-Calvo, Marie-Christine Birling, Juan María Torres, Juan Carlos Espinosa, Alba Marín-Moreno

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), ⟨10.1038/s41598-019-52155-z⟩

Cynomolgus macaque has been used for the evaluation of the zoonotic potential of prion diseases, especially for classical-Bovine Spongiform Encephalopathy (classical-BSE) infectious agent. PrP amino acid sequence is considered to play a key role in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c387fd7cee7f59b0d416a84062c023de
http://link.springer.com/article/10.1038/s41598-019-52155-z

Update on chronic wasting disease (CWD) III

Autor: EFSA Panel on Biological Hazards (BIOHAZ), Kostas Koutsoumanis, Ana Allende, Avelino Alvarez‐Ordoňez, Declan Bolton, Sara Bover‐Cid, Marianne Chemaly, Robert Davies, Alessandra De Cesare, Lieve Herman, Friederike Hilbert, Roland Lindqvist, Maarten Nauta, Luisa Peixe, Giuseppe Ru, Panagiotis Skandamis, Elisabetta Suffredini, Olivier Andreoletti, Sylvie L Benestad, Emmanuel Comoy, Romolo Nonno, Teresa da Silva Felicio, Angel Ortiz‐Pelaez, Marion M Simmons

Publikováno v: EFSA Journal
Koutsoumanis, K, Allende, A, Alvarez-Ordoňez, A, Bolton, D, Bover-Cid, S, Chemaly, M, Davies, R, De Cesare, A, Herman, L, Hilbert, F, Lindqvist, R, Nauta, M, Peixe, L, Ru, G, Skandamis, P, Suffredini, E, Andreoletti, O, Benestad, S L, Comoy, E, Nonno, R, da Silva Felicio, T, Ortiz-Pelaez, A & Simmons, M M 2019, ' Update on chronic wasting disease (CWD) III ', EFSA Journal, vol. 17, no. 11, 5863 . https://doi.org/10.2903/j.efsa.2019.5863
EFSA Journal, Vol 17, Iss 11, Pp n/a-n/a (2019)

The European Commission asked EFSA for a Scientific Opinion: to revise the state of knowledge about the differences between the chronic wasting disease (CWD) strains found in North America (NA) and Europe and within Europe; to review new scientific e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ab7cdd5f2958e5b5ed41810fddaa3c
https://pubmed.ncbi.nlm.nih.gov/32626163

Colloidal gel as an efficient process to treat Chemical, Biological, Radiological (CBR) and prion contaminated solid surfaces

Autor: Esther Le Toquin, Amélie Ludwig, Marie-Sophie Charvolin, Agnès Grandjean, Célia Lepeytre, Fabien Frances, Alban Gossard, Emmanuel Comoy

Publikováno v: Chemical Engineering Science. 246:116957

Chemical, biological, radiological and nuclear (CBRN) accidents or attacks typically disseminate contaminants inside and outside buildings and structures whose surfaces have to be decontaminated. This paper describes an innovative colloidal gel formu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0f96a52dedada4aab5fd21e0475ea6f
https://doi.org/10.1016/j.ces.2021.116957