Prediction of RNA subcellular localization: Learning from heterogeneous data sources

Autor: Anca Flavia Savulescu, Emmanuel Bouilhol, Nicolas Beaume, Macha Nikolski

Publikováno v: iScience, Vol 24, Iss 11, Pp 103298- (2021)

Summary: RNA subcellular localization has recently emerged as a widespread phenomenon, which may apply to the majority of RNAs. The two main sources of data for characterization of RNA localization are sequence features and microscopy images, such as

Externí odkaz: https://doaj.org/article/c13daf0585c841d29ced38766221a951

Interrogating RNA and protein spatial subcellular distribution in smFISH data with DypFISH

Autor: Jan Schmoranzer, Nicolas Beaume, Mafalda R. Pimentel, Jonathan Warrell, Macha Nikolski, Anca F. Savulescu, Mikaël Boulle, Emmanuel Bouilhol, Edgar R. Gomes, Stephane Dallongeville, Fabrice Agou, Jean-Christophe Olivo-Marin, Musa M. Mhlanga, Isabela C Fortunato, Claudio A. Franco, Hayssam Soueidan, Benjamin Dartigues, Robyn Brackin

Publikováno v: Cell Reports Methods
Cell Reports Methods, 2021, 1 (5), pp.100068. ⟨10.1016/j.crmeth.2021.100068⟩
Cell Reports Methods, 1, 5, pp. 1-30
Cell Reports Methods, 1, 1-30
Cell Reports Methods, Cell Press Elsevier, In press, ⟨10.1016/j.crmeth.2021.100068⟩

International audience; Advances in single-cell RNA sequencing have allowed for the identification of cellular subtypes on the basis of quantification of the number of transcripts in each cell. However, cells might also differ in the spatial distribu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a3705a6d4773860f9a8b56164911b0
https://doi.org/10.1016/j.crmeth.2021.100068

DeepSpot: a deep neural network for RNA spot enhancement in smFISH microscopy images

Autor: Emmanuel Bouilhol, Benjamin Dartigues, Robyn Brackin, Macha Nikolski, Anca F. Savulescu, Edgar Lefevre

Detection of RNA spots in single molecule FISH microscopy images remains a difficult task especially when applied to large volumes of data. The small size of RNA spots combined with high noise level of images often requires a manual adaptation of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdfa6c411da0ef6d330092d51e7a581f
https://doi.org/10.1101/2021.11.25.469984

FluoSim: simulator of single molecule dynamics for fluorescence live-cell and super-resolution imaging of membrane proteins

Autor: Emmanuel Bouilhol, Ingrid Chamma, Olivier Thoumine, Macha Nikolski, Matthieu Lagardère

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2020, 10, ⟨10.1038/s41598-020-75814-y⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)

International audience; Fluorescence live-cell and super-resolution microscopy methods have considerably advanced our understanding of the dynamics and mesoscale organization of macro-molecular complexes that drive cellular functions. However, differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6446f8edb1643f43231a5f3497350c
https://hal.archives-ouvertes.fr/hal-02996252

Genome Sequences of Two Tunisian Field Strains of Avian Mycoplasma, M. meleagridis and M. gallinarum

Autor: Emmanuel Bouilhol, Boutheina Ben Abdelmoumen Mardassi, Alain Blanchard, Pascal Sirand-Pugnet, Aurélien Barré, Christophe Hubert, Florence Maurier, Elhem Yacoub

Publikováno v: Genome Announcements
Genome Announcements, American Society for Microbiology, 2016, 4 (3), pp.e00558-16. ⟨10.1128/genomeA.00558-16⟩

Mycoplasma meleagridis and Mycoplasma gallinarum are bacteria that affect birds, but little is known about the genetic basis of their interaction with chickens and other poultry. Here, we sequenced the genomes of M. meleagridis strain MM_26B8_IPT and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6578186354892244fed546c5d75b058
https://hal-riip.archives-ouvertes.fr/pasteur-02015202/document