Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Emmanuel Amzallag"'
Autor:
Emmanuel Amzallag, Eran Hornstein
Publikováno v:
Cells, Vol 11, Iss 15, p 2415 (2022)
Proper homeostasis of the proteome, referred to as proteostasis, is maintained by chaperone-dependent refolding of misfolded proteins and by protein degradation via the ubiquitin-proteasome system and the autophagic machinery. This review will discus
Externí odkaz:
https://doaj.org/article/15be2a79f1e3409ea5b6988c6e90def0
Autor:
Amir Bahat, Andres Goldman, Yehudit Zaltsman, Dilshad H. Khan, Coral Halperin, Emmanuel Amzallag, Vladislav Krupalnik, Michael Mullokandov, Alon Silberman, Ayelet Erez, Aaron D. Schimmer, Jacob H. Hanna, Atan Gross
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Reprogramming of mitochondria metabolism occurs during naïve to primed pluripotency differentiation in mouse embryonic stem cells (ESCs). Here the authors show that mitochondrial MTCH2 regulates mitochondrial fusion and that this fusion is required
Externí odkaz:
https://doaj.org/article/3b42662e2cea47e7be6870e3d559ad27
Autor:
Michael Mullokandov, Jacob H. Hanna, Dilshad H. Khan, Atan Gross, Emmanuel Amzallag, Yehudit Zaltsman, Amir Bahat, Vladislav Krupalnik, Coral Halperin, Ayelet Erez, Andres Goldman, Alon Silberman, Aaron D. Schimmer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
The role of mitochondria dynamics and its molecular regulators remains largely unknown during naïve-to-primed pluripotent cell interconversion. Here we report that mitochondrial MTCH2 is a regulator of mitochondrial fusion, essential for the naïve-
Autor:
Tamar Eigler, Giulia Zarfati, Emmanuel Amzallag, Sansrity Sinha, Nadav Segev, Yishaia Zabary, Assaf Zaritsky, Avraham Shakked, Kfir-Baruch Umansky, Eyal D. Schejter, Douglas P. Millay, Eldad Tzahor, Ori Avinoam
Publikováno v:
Developmental Cell
Dev Cell
Dev Cell
Summary Myoblast fusion is essential for muscle development and regeneration. Yet, it remains poorly understood how mononucleated myoblasts fuse with preexisting fibers. We demonstrate that ERK1/2 inhibition (ERKi) induces robust differentiation and