Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Emmanouil Papasavvas"'
Autor:
David S. Lakomy, Juliana Wu, Dorothy Lombe, Emmanouil Papasavvas, Susan Citonje Msadabwe, Yimin Geng, Luis J. Montaner, Elizabeth Chiao, Lilie L. Lin
Publikováno v:
Cancer Medicine, Vol 10, Iss 13, Pp 4206-4220 (2021)
Abstract Background Immune markers have been correlated with prognosis in a variety of solid tumors, including cervical cancer. Objective To review the literature on hematologic and immune markers and their association with recurrence and survival am
Externí odkaz:
https://doaj.org/article/e855cd46b0c34159af90a19aa6c9f343
Autor:
Leila B. Giron, Clovis S. Palmer, Qin Liu, Xiangfan Yin, Emmanouil Papasavvas, Radwa Sharaf, Behzad Etemad, Mohammad Damra, Aaron R. Goldman, Hsin-Yao Tang, Rowena Johnston, Karam Mounzer, Jay R. Kostman, Pablo Tebas, Alan Landay, Luis J. Montaner, Jeffrey M. Jacobson, Jonathan Z. Li, Mohamed Abdel-Mohsen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Current HIV cure-focused clinical trials rely on analytic treatment interruption (ATI) to evaluate post-treatment control (PTC). Here, combining untargetted metabolomics and glycomics in two HIV clinical cohorts, in vitro assays, and machine learning
Externí odkaz:
https://doaj.org/article/8389144aeb1a4d6d950f9fd144f01fe1
Autor:
Leila B. Giron, Emmanouil Papasavvas, Xiangfan Yin, Aaron R. Goldman, Hsin-Yao Tang, Clovis S. Palmer, Alan L. Landay, Jonathan Z. Li, John R. Koethe, Karam Mounzer, Jay R. Kostman, Qin Liu, Luis J. Montaner, Mohamed Abdel-Mohsen
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
The likelihood of HIV rebound after stopping antiretroviral therapy (ART) is a combination of the size of HIV reservoirs that persist despite ART and the host immunological and inflammatory factors that control these reservoirs. Therefore, there is a
Externí odkaz:
https://doaj.org/article/0fa9e9d892ae46d3801779a44629a2bb
Autor:
Leila B. Giron, Florent Colomb, Emmanouil Papasavvas, Livio Azzoni, Xiangfan Yin, Matthew Fair, Alitzel Anzurez, Mohammad Damra, Karam Mounzer, Jay R. Kostman, Pablo Tebas, Una O'Doherty, Hiroaki Tateno, Qin Liu, Michael R. Betts, Luis J. Montaner, Mohamed Abdel-Mohsen
Publikováno v:
EBioMedicine, Vol 59, Iss , Pp 102945- (2020)
Background: A comprehensive understanding of host factors modulated by the antiviral cytokine interferon-α (IFNα) is imperative for harnessing its beneficial effects while avoiding its detrimental side-effects during HIV infection. Cytokines modula
Externí odkaz:
https://doaj.org/article/fab31996f60c46fa9d6c34db3d611550
Autor:
Florent Colomb, Leila B. Giron, Thomas A. Premeaux, Brooks I. Mitchell, Toshiro Niki, Emmanouil Papasavvas, Luis J. Montaner, Lishomwa C. Ndhlovu, Mohamed Abdel-Mohsen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Endogenous plasma levels of the immunomodulatory carbohydrate-binding protein galectin-9 (Gal-9) are elevated during HIV infection and remain elevated after antiretroviral therapy (ART) suppression. We recently reported that Gal-9 regulates HIV trans
Externí odkaz:
https://doaj.org/article/3d2e327c70ed42f084495df2abed41f0
Autor:
Livio Azzoni, Russell Barbour, Emmanouil Papasavvas, Deborah K Glencross, Wendy S Stevens, Mark F Cotton, Avy Violari, Luis J Montaner
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145320 (2015)
Early initiation of anti-retroviral treatment (ART) decreases mortality as compared to deferred treatment, but whether it preserves immune cells from early loss or promotes their recovery remains undefined. Determination of complex immunological endp
Externí odkaz:
https://doaj.org/article/4e8c520527c841d1a27215c802f0baee
Autor:
Emmanouil Papasavvas, Jay R Kostman, Karam Mounzer, Robert M Grant, Robert Gross, Cele Gallo, Livio Azzoni, Andrea Foulkes, Brian Thiel, Maxwell Pistilli, Agnieszka Mackiewicz, Jane Shull, Luis J Montaner
Publikováno v:
PLoS Medicine, Vol 1, Iss 3, p e64 (2004)
Approaches to limiting exposure to antiretroviral therapy (ART) drugs are an active area of HIV therapy research. Here we present longitudinal follow-up of a randomized, open-label, single-center study of the immune, viral, and safety outcomes of str
Externí odkaz:
https://doaj.org/article/887a1059938d4439af84b361bf00a964
Autor:
Livio Azzoni, Nigel J Crowther, Cynthia Firnhaber, Andrea S Foulkes, Xiangfan Yin, Deborah Glencross, Robert Gross, Mitch D Kaplan, Emmanouil Papasavvas, Doreen Schulze, Wendy Stevens, Tessa van derMerwe, Rita Waisberg, Ian Sanne, Luis J Montaner
Publikováno v:
Journal of the International AIDS Society, Vol 13, Iss 1, Pp 33-33 (2010)
Background Advanced HIV infection can result in lipoatrophy and wasting, even in the absence of ongoing opportunistic infections, suggesting that HIV may directly affect adipose tissue amount and distribution. Methods We assessed the relationship of
Externí odkaz:
https://doaj.org/article/257e4e38efae404da4a1223f7746eb4e
Autor:
Pablo Tebas, Kenn Lynn, Livio Azzoni, Giorgio Cocchella, Emmanouil Papasavvas, Matthew Fair, Brijesh Karanam, Paridhima Sharma, Jacqueline D. Reeves, Christos J. Petropoulos, Linden Lalley-Chareczko, Jay R. Kostman, Willian Short, Karam Mounzer, Luis J. Montaner
Publikováno v:
AIDS.
Autor:
Steven M. Albelda, Corey J. Langer, Melissa Culligan, Charles B. Simone, Keith A. Cengel, Luis J. Montaner, Paul Kennedy, Emmanouil Papasavvas, Kay See Tan, Jennifer H. Yearley, Leslie Litzky, Wei-Ting Hwang, Daniel F. Heitjan, Jing Sun, Sharyn I. Katz, Anil Vachani, Andrew R. Haas, Edmund K. Moon, Adri Recio, Susan Metzger, Joseph Friedberg, James P. Stevenson, Evan Alley, Daniel H. Sterman
Purpose: “In situ vaccination” using immunogene therapy has the ability to induce polyclonal antitumor responses directed by the patient's immune system.Experimental Design: Patients with unresectable malignant pleural mesothelioma (MPM) received
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2810b59165230c7ab9401119d8a2979b
https://doi.org/10.1158/1078-0432.c.6523496.v1
https://doi.org/10.1158/1078-0432.c.6523496.v1