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pro vyhledávání: '"Emma eWrightson"'
Autor:
Melanie eSweetlove, Emma eWrightson, Sharada eKolekar, Gordon W. Rewcastle, Bruce C. Baguley, Peter R. Shepherd, Stephen M. F. Jamieson
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
BRAF and MEK inhibitors have improved outcomes for patients with BRAF-mutant melanoma, but their efficacy is limited by both intrinsic and acquired resistance. Activation of the PI3K pathway can mediate resistance to these agents, providing a strong
Externí odkaz:
https://doaj.org/article/1641ec95a3114884a208b73af6af7e24