Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Emma Veronica, Carsana"'
Autor:
Giulia Lunghi, Erika Di Biase, Emma Veronica Carsana, Alexandre Henriques, Noelle Callizot, Laura Mauri, Maria Grazia Ciampa, Luigi Mari, Nicoletta Loberto, Massimo Aureli, Sandro Sonnino, Michael Spedding, Elena Chiricozzi, Maria Fazzari
Publikováno v:
FEBS Open Bio, Vol 13, Iss 12, Pp 2324-2341 (2023)
Alterations in glycosphingolipid metabolism have been linked to the pathophysiological mechanisms of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease affecting motor neurons. Accordingly, administration of GM1, a sialic acid‐contain
Externí odkaz:
https://doaj.org/article/bc90ee2630b94cd7baec16a20f019b9f
Autor:
Maria Fazzari, Giulia Lunghi, Alexandre Henriques, Noëlle Callizot, Maria Grazia Ciampa, Laura Mauri, Simona Prioni, Emma Veronica Carsana, Nicoletta Loberto, Massimo Aureli, Luigi Mari, Sandro Sonnino, Elena Chiricozzi, Erika Di Biase
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1305 (2023)
Past evidence has shown that the exogenous administration of GM1 ganglioside slowed neuronal death in preclinical models of Parkinson’s disease, a neurodegenerative disorder characterized by the progressive loss of dopamine-producing neurons: howev
Externí odkaz:
https://doaj.org/article/8a1943fc716f42f4923a8d9f878d1326
Autor:
Emma Veronica Carsana, Matteo Audano, Silvia Breviario, Silvia Pedretti, Massimo Aureli, Giulia Lunghi, Nico Mitro
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2069 (2022)
In recent years, the availability of induced pluripotent stem cell-based neuronal models has opened new perspectives on the study and therapy of neurological diseases such as Parkinson’s disease. In particular, P. Zhang set up a protocol to efficie
Externí odkaz:
https://doaj.org/article/817e3feb8c644c4a86a3f17d0da40b98
Autor:
Giulia Lunghi, Emma Veronica Carsana, Nicoletta Loberto, Laura Cioccarelli, Simona Prioni, Laura Mauri, Rosaria Bassi, Stefano Duga, Letizia Straniero, Rosanna Asselta, Giulia Soldà, Alessio Di Fonzo, Emanuele Frattini, Manuela Magni, Nara Liessi, Andrea Armirotti, Elena Ferrari, Maura Samarani, Massimo Aureli
Publikováno v:
Cells, Vol 11, Iss 15, p 2343 (2022)
β-glucocerebrosidase is a lysosomal hydrolase involved in the catabolism of the sphingolipid glucosylceramide. Biallelic loss of function mutations in this enzyme are responsible for the onset of Gaucher disease, while monoallelic β-glucocerebrosid
Externí odkaz:
https://doaj.org/article/0c02205b205142f68964b014a1490b02
Autor:
Massimo Aureli, Laura Mauri, Emma Veronica Carsana, Dorina Dobi, Silvia Breviario, Giulia Lunghi, Sandro Sonnino
Publikováno v:
Advances in Neurobiology ISBN: 9783031123894
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec42f8fb38d9b8b8b3fa13e71f148ddf
https://doi.org/10.1007/978-3-031-12390-0_11
https://doi.org/10.1007/978-3-031-12390-0_11
Autor:
Massimo, Aureli, Laura, Mauri, Emma Veronica, Carsana, Dorina, Dobi, Silvia, Breviario, Giulia, Lunghi, Sandro, Sonnino
Publikováno v:
Advances in neurobiology. 29
Gangliosides are a large group of complex lipids found predominantly in the outer layer of the plasma membrane of cells, particularly abundant in nerve endings. Their half-life in the nervous system is short, and their membrane composition and conten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::903604edee4eb8d476144ef999cfefdb
https://pubmed.ncbi.nlm.nih.gov/36255680
https://pubmed.ncbi.nlm.nih.gov/36255680
Autor:
Mitro, Emma Veronica Carsana, Matteo Audano, Silvia Breviario, Silvia Pedretti, Massimo Aureli, Giulia Lunghi, Nico
Publikováno v:
Biomedicines; Volume 10; Issue 9; Pages: 2069
In recent years, the availability of induced pluripotent stem cell-based neuronal models has opened new perspectives on the study and therapy of neurological diseases such as Parkinson’s disease. In particular, P. Zhang set up a protocol to efficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::aac9ee9ffb4928c078d2969d32f57bf2
Autor:
Aureli, Giulia Lunghi, Emma Veronica Carsana, Nicoletta Loberto, Laura Cioccarelli, Simona Prioni, Laura Mauri, Rosaria Bassi, Stefano Duga, Letizia Straniero, Rosanna Asselta, Giulia Soldà, Alessio Di Fonzo, Emanuele Frattini, Manuela Magni, Nara Liessi, Andrea Armirotti, Elena Ferrari, Maura Samarani, Massimo
Publikováno v:
Cells; Volume 11; Issue 15; Pages: 2343
β-glucocerebrosidase is a lysosomal hydrolase involved in the catabolism of the sphingolipid glucosylceramide. Biallelic loss of function mutations in this enzyme are responsible for the onset of Gaucher disease, while monoallelic β-glucocerebrosid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::0152f3a5a2c6159c75ff3dc9e50bc084
Autor:
Emma Veronica Carsana, Giulia Lunghi, Simona Prioni, Laura Mauri, Nicoletta Loberto, Alessandro Prinetti, Fabio Andrea Zucca, Rosaria Bassi, Sandro Sonnino, Elena Chiricozzi, Stefano Duga, Letizia Straniero, Rosanna Asselta, Giulia Soldà, Maura Samarani, Massimo Aureli
Niemann-Pick type A disease (NPA) is a rare lysosomal storage disorder caused by mutations in the gene coding for the lysosomal enzyme acid sphingomyelinase (ASM). ASM deficiency leads to the consequent accumulation of its uncatabolized substrate, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970f1ce630e730724c630707fe382554
https://hdl.handle.net/2434/944971
https://hdl.handle.net/2434/944971
Autor:
Gigliola Fagiolari, Manuela Garbellini, Edoardo Monfrini, Sabrina Salani, Alessio Di Fonzo, Filippo Cogiamanian, Giacomo P. Comi, Linda Borellini, Maurizio Moggio, Fabio Biella, Massimo Aureli, Stefania Corti, Emma Veronica Carsana, Letizia Straniero, Stefano Duga, Nereo Bresolin
Publikováno v:
Annals of Neurology
In this work, we describe the association of a novel homozygous VPS11 variant with adult-onset generalized dystonia, providing a detailed clinical report and biological evidence of disease mechanism. Vps11 is a subunit of the homotypic fusion and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0c8012630786759205219d792e6eef
https://doi.org/10.1002/ana.26021
https://doi.org/10.1002/ana.26021