Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Emma V. Yates"'
Autor:
Tuomas P. J. Knowles, Tuuli A. Hakala, Zenon Toprakcioglu, Christopher M. Dobson, Emma V. Yates, Karthik Nadendla, Dijana Matak-Vinkovic, Francisco Corzana, Gonçalo J. L. Bernardes, Pavan K. Challa, Rodrigo Martínez
Publikováno v:
Journal of the American Chemical Society
Funder: Frances and Augustus Newman Foundation
Funder: Emmanuel College, University of Cambridge
Funder: Biotechnology and Biological Sciences Research Council
Funder: Centre for Misfolding Diseases, University of Cambridge
Funder
Funder: Emmanuel College, University of Cambridge
Funder: Biotechnology and Biological Sciences Research Council
Funder: Centre for Misfolding Diseases, University of Cambridge
Funder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c11a8321fa45d94bf1d8012e6e99a46
Autor:
Jenny Dworzak, Benoît Renvoisé, Johnny Habchi, Emma V Yates, Christophe Combadière, Tuomas P Knowles, Christopher M Dobson, Craig Blackstone, Ole Paulsen, Philip M Murphy
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127730 (2015)
Cx3cr1, the receptor for the chemokine Cx3cl1 (fractalkine), has been implicated in the progression and severity of Alzheimer's disease-like pathology in mice, but the underlying mechanisms remain unclear. A complicating factor is that Cx3cr1 has bee
Externí odkaz:
https://doaj.org/article/ffe644bd90094fc3a750f74851bfe2dc
Autor:
Tuomas P. J. Knowles, Liu Hong, Georg Meisl, Emma V. Yates, Kadi L. Saar, Yuewen Zhang, Christopher M. Dobson
Publikováno v:
Chemical Science. 9:3503-3507
Investigations of protein folding, unfolding and stability are critical for the understanding of the molecular basis of biological structure and function. We describe here a microfluidic approach to probe the unfolding of unlabelled protein molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327f7e083c2e4cc36af03e94e7f3d174
https://doi.org/10.1039/c7sc04331g
https://doi.org/10.1039/c7sc04331g
Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Péclet Numbers
Autor:
Thomas Müller, Luke Rajah, Michele Vendruscolo, Emma V. Yates, Paolo Arosio, Christopher M. Dobson, Tuomas P. J. Knowles, Samuel I. A. Cohen
Publikováno v:
International Journal of Nonlinear Sciences and Numerical Simulation. 17:175-183
Conventional approaches for simulating steady-state distributions of dilute particles under diffusive and advective transport involve solving the diffusion and advection equations in at least two dimensions. Here, we present an alternative computatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ecb4b4c40a7a75239669e953f40d864
https://doi.org/10.1515/ijnsns-2015-0056
https://doi.org/10.1515/ijnsns-2015-0056
Autor:
Urszula, Łapińska, Kadi L, Saar, Emma V, Yates, Therese W, Herling, Thomas, Müller, Pavan K, Challa, Christopher M, Dobson, Tuomas P J, Knowles
Publikováno v:
Physical chemistry chemical physics : PCCP. 19(34)
The isoelectric point (pI) of a protein is a key characteristic that influences its overall electrostatic behaviour. The majority of conventional methods for the determination of the isoelectric point of a molecule rely on the use of spatial gradient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ba59a2472c7b040051e191d8d5980de
https://pubmed.ncbi.nlm.nih.gov/28817152
https://pubmed.ncbi.nlm.nih.gov/28817152
Publikováno v:
The Journal of Physical Chemistry. B
We have explored amyloid formation using poly(amino acid) model systems in which differences in peptide secondary structure and hydrophobicity can be introduced in a controlled manner. We show that an environmentally sensitive fluorescent dye, dapoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c669452da01c31cb54658ee323d62c71
https://pubmed.ncbi.nlm.nih.gov/26865546
https://pubmed.ncbi.nlm.nih.gov/26865546
Autor:
Emma V. Yates, Paolo Arosio, Erwin De Genst, Therese W. Herling, Christopher M. Dobson, Francesco A. Aprile, Thomas Müller, Duncan A. White, Luke Rajah, Samuel I. A. Cohen, Tuomas P. J. Knowles, Yingbo Zhang, Michele Vendruscolo, Sara Linse
Publikováno v:
ACS nano. 10(1)
Characterizing the sizes and interactions of macromolecules under native conditions is a challenging problem in many areas of molecular sciences, which fundamentally arises from the polydisperse nature of biomolecular mixtures. Here, we describe a mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c111d1478a71f0107de7c375c4f84f
https://pubmed.ncbi.nlm.nih.gov/26678709
https://pubmed.ncbi.nlm.nih.gov/26678709
Autor:
Tuomas P. J. Knowles, Thomas Müller, Michele Vendruscolo, Luke Rajah, Christopher M. Dobson, Sara Linse, Erwin De Genst, Emma V. Yates, Paolo Arosio
The study of biomolecular interactions is central to an understanding of function, malfunction and therapeutic modulation of biological systems, yet often involves a compromise between sensitivity and accuracy. Many conventional analytical steps and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4840439a3def52ba9cef9bdca21730
https://www.repository.cam.ac.uk/handle/1810/267245
https://www.repository.cam.ac.uk/handle/1810/267245
Autor:
Craig Blackstone, Christophe Combadière, Ole Paulsen, Philip M. Murphy, Emma V. Yates, Jenny Dworzak, Tuomas P. J. Knowles, Johnny Habchi, Christopher M. Dobson, Benoît Renvoisé
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0127730 (2015)
PLoS ONE
PLoS ONE
Cx3cr1, the receptor for the chemokine Cx3cl1 (fractalkine), has been implicated in the progression and severity of Alzheimer’s disease-like pathology in mice, but the underlying mechanisms remain unclear. A complicating factor is that Cx3cr1 has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4edf7fccf9d0398f89b75a0ecb0d5f21
http://europepmc.org/articles/PMC4454597?pdf=render
http://europepmc.org/articles/PMC4454597?pdf=render
Autor:
Li Sun, John Malona, Emma V. Yates, Erik J. Sorensen, Daniel Montiel, Haw Yang, Marissa M. Sampias
Publikováno v:
Nanomaterial Interfaces in Biology ISBN: 9781627034616
Silver and large gold nanoparticles are more efficient scatterers than smaller particles, which can be advantageous for a variety of single-particle-based sensing and spectroscopic applications. The increased susceptibility to surface oxidation and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f6954281d8c85f8ae011f64e7c50d3
https://doi.org/10.1007/978-1-62703-462-3_18
https://doi.org/10.1007/978-1-62703-462-3_18