Distinct Roles of Extracellular Domains in the Epstein-Barr Virus-Encoded BILF1 Receptor for Signaling and Major Histocompatibility Complex Class I Downregulation

Autor: Suzan Fares, Katja Spiess, Emma T. B. Olesen, Jianmin Zuo, Sarah Jackson, Thomas N. Kledal, Mark R. Wills, Mette M. Rosenkilde

Publikováno v: mBio, Vol 10, Iss 1 (2019)

ABSTRACT The Epstein-Barr virus (EBV) BILF1 gene encodes a constitutively active G protein-coupled receptor (GPCR) that downregulates major histocompatibility complex (MHC) class I and induces signaling-dependent tumorigenesis. Different BILF1 homolo

Externí odkaz: https://doaj.org/article/dee11feb9d2349f88db72d5cfb52eacb

A Vasopressin-Induced Change in Prostaglandin Receptor Subtype Expression Explains the Differential Effect of PGE

Autor: Peter M T, Deen, Michelle, Boone, Horst, Schweer, Emma T B, Olesen, Claudia, Carmone, Jack F M, Wetzels, Robert A, Fenton, Marleen L A, Kortenoeven

Publikováno v: Frontiers in Physiology

Arginine vasopressin (AVP) stimulates the concentration of renal urine by increasing the principal cell expression of aquaporin-2 (AQP2) water channels. Prostaglandin E2 (PGE2) and prostaglandin2α (PGF2α) increase the water absorption of the princi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3720eb338648e1402c238e107f220bf8
https://pubmed.ncbi.nlm.nih.gov/35126177

Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter

Autor: Qi Wu, Robert A. Fenton, Emma T. B. Olesen, Trairak Pisitkun, Timo Rieg, Henrik Dimke, Li Peng, Cristina Esteva-Font, L. M. Fredrik Leeb-Lundberg, Lei Cheng, Søren Brandt Poulsen, Björn Olde

Publikováno v: Cheng, L, Poulsen, S B, Wu, Q, Esteva-Font, C, Olesen, E T B, Peng, L, Olde, B, Leeb-Lundberg, L M F, Pisitkun, T, Rieg, T, Dimke, H & Fenton, R A 2019, ' Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter ', Journal of the American Society of Nephrology : JASN, vol. 30, no. 8, pp. 1454-1470 . https://doi.org/10.1681/ASN.2018101025
Cheng, L, Poulsen, S B, Wu, Q, Esteva-Font, C, Olesen, E T B, Peng, L, Olde, B, Leeb-Lundberg, L M F, Pisitkun, T, Rieg, T, Dimke, H & Fenton, R A 2019, ' Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter ', Journal of the American Society of Nephrology, vol. 30, no. 8, pp. 1454-1470 . https://doi.org/10.1681/ASN.2018101025
J Am Soc Nephrol
Cheng, L, Poulsen, S B, Wu, Q, Esteva Font, C, Olesen, E T B, Peng, L, Olde, B, Leeb-Lundberg, F, Pisitkun, T, Rieg, T, Dimke, H & Fenton, R A 2019, ' Rapid aldosterone-mediated signaling in the DCT increases activity of the thiazide-sensitive NaCl cotransporter ', Journal of the American Society of Nephrology : JASN .
Journal of the American Society of Nephrology

BACKGROUND: The NaCl cotransporter NCC in the kidney distal convoluted tubule (DCT) regulates urinary NaCl excretion and BP. Aldosterone increases NaCl reabsorption via NCC over the long-term by altering gene expression. But the acute effects of aldo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b9536e3bc1eb1f4d43d4d0df5be675
https://pure.au.dk/portal/da/publications/rapid-aldosteronemediated-signaling-in-the-dct-increases-activity-of-the-thiazidesensitive-nacl-cotransporter(4f90fbf0-9295-432d-b6a8-ab66f9e7bda9).html

The vasopressin type 2 receptor and prostaglandin receptors EP2 and EP4 can increase aquaporin-2 plasma membrane targeting through a cAMP-independent pathway

Autor: Robert A. Fenton, Emma T. B. Olesen, Mette Assentoft, Hanne B. Moeller, Nanna MacAulay

Publikováno v: Olesen, E T B, Moeller, H B, Assentoft, M, MacAulay, N & Fenton, R A 2016, ' The vasopressin type 2 receptor and prostaglandin receptors EP2 and EP4 can increase aquaporin-2 plasma membrane targeting through a cAMP-independent pathway ', American Journal of Physiology: Renal Physiology, vol. 311, no. 5, 311, pp. F935-F944 . https://doi.org/10.1152/ajprenal.00559.2015

Apical membrane targeting of the collecting duct water channel aquaporin-2 (AQP2) is essential for body water balance. As this event is regulated by Gs coupled 7-transmembrane receptors such as the vasopressin type 2 receptor (V2R) and the prostanoid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d6b543d9599bfd176a0d457e6a01b52
https://doi.org/10.1152/ajprenal.00559.2015

Aquaporin-2 membrane targeting: still a conundrum

Autor: Robert A. Fenton, Emma T. B. Olesen

Publikováno v: Olesen, E T B & Fenton, R A 2017, ' Aquaporin-2 membrane targeting : still a conundrum ', American Journal of Physiology: Renal Physiology, vol. 312, no. 4, pp. F744-F747 . https://doi.org/10.1152/ajprenal.00010.2017

The targeting of the water channel aquaporin-2 (AQP2) to the apical plasma membrane of kidney collecting duct principal cells is regulated mainly by the antidiuretic peptide hormone arginine vasopressin (AVP). This process is of crucial importance fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6749a372e5ab4a2c912022676a03210
https://pubmed.ncbi.nlm.nih.gov/28179252