Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Emma Sweetland"'
Autor:
Alison T. Merryweather-Clarke, Robson Kjh., Lisa Schimanski, Emma Sweetland, Benedikt M. Kessler, D Rezgui, Townsend Arm., J Bastin, Hal Drakesmith, Mariola J. Edelmann
Hereditary hemochromatosis is most frequently associated with mutations in HFE, which encodes a class Ib histocompatibility protein. HFE binds to the transferrin receptor-1 (TfR1) in competition with iron-loaded transferrin (Fe–Tf). HFE is released
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2796c5a6c4ed1d65aa1922d0ec911e1
https://ora.ox.ac.uk/objects/uuid:7c4db443-9fe9-4bb3-a4d5-7692a800b930
https://ora.ox.ac.uk/objects/uuid:7c4db443-9fe9-4bb3-a4d5-7692a800b930
Autor:
Townsend Arm., J Bastin, K Horne, Lisa Schimanski, Emma Sweetland, Diana Cowley, Hal Drakesmith, C Talbott, John R. James, Simon J. Davis
Publikováno v:
Blood Cells, Molecules, and Diseases. 40:360-369
Ferroportin is a multi-transmembrane glycoprotein that mediates iron export from cells. Mutations in ferroportin are linked to type IV hemochromatosis, a dominantly inherited disorder of iron metabolism. Multimers of ferroportin, whose existence may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fae9ce2f07f1b63995fb4260f0d9dce
https://doi.org/10.1016/j.bcmd.2007.09.007
https://doi.org/10.1016/j.bcmd.2007.09.007
In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations
Autor:
Yingyong Chinthammitr, Hal Drakesmith, Alison T. Merryweather-Clarke, Kathryn J. H. Robson, Jon P. Edwards, Diana Cowley, Emma Sweetland, Vip Viprakasit, Lisa Schimanski, J Bastin, Alain Townsend
Publikováno v:
Blood. 105:4096-4102
Type IV hemochromatosis is associated with dominant mutations in the SLC40A1 gene encoding ferroportin (FPN). Known as the “ferroportin disease,” this condition is typically characterized by high serum ferritin, reduced transferrin saturation, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b311cdd8f432b8f1237cdfba18e531
https://doi.org/10.1182/blood-2004-11-4502
https://doi.org/10.1182/blood-2004-11-4502
Autor:
Emma Sweetland, J Bastin, Mubeen Ashraf, Jon P. Edwards, Alain Townsend, Hal Drakesmith, Lisa Schimanski, Diana Cowley
Hereditary hemochromatosis (HH) is a disorder of iron metabolism caused by common mutations in the gene HFE . The HFE protein binds to transferrin receptor-1 (TfR1) in competition with transferrin, and in vitro , reduces cellular iron by reducing iro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0402c9e3974f02a98b4d3df9e6a7136
https://europepmc.org/articles/PMC137763/
https://europepmc.org/articles/PMC137763/
Autor:
Chuan He, Emma Sweetland
Publikováno v:
SAE Technical Paper Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5ea6ae791e5d331af055ec6dd9d8529
https://doi.org/10.4271/973181
https://doi.org/10.4271/973181