Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Emma Sparr"'
Publikováno v:
JACS Au, Vol 4, Iss 4, Pp 1250-1262 (2024)
Externí odkaz:
https://doaj.org/article/ba382113cc6443619aa3b02c1ce60f8e
Autor:
Alexandra Andersson, Marco Fornasier, Katarzyna Makasewicz, Tinna Pálmadóttir, Sara Linse, Emma Sparr, Peter Jönsson
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Interactions of lipid vesicles play important roles in a large variety of functions and dysfunctions in the human body. Vital for several biochemical functions is the interaction between monomeric proteins and lipid membranes, and the induced phenome
Externí odkaz:
https://doaj.org/article/e6bf2404c8714d98aa99689e2d37eead
Autor:
Elisabeth Bankell, Xiaoyan Liu, Martin Lundqvist, Daniel Svensson, Karl Swärd, Emma Sparr, Bengt-Olof Nilsson
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101192- (2022)
The human antimicrobial peptide LL-37 permeabilizes the plasma membrane of host cells, but LL-37-induced direct effects on mitochondrial membrane permeability and function has not been reported. Here, we demonstrate that LL-37 is rapidly (within 20 m
Externí odkaz:
https://doaj.org/article/e39d840cc5aa4bf58cdeaa353c644834
Autor:
Jenny Marie Andersson, Quoc Dat Pham, Helena Mateos, Sylvia Eriksson, Pia Harryson, Emma Sparr
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 7, Pp 1014-1024 (2020)
A major challenge to plant growth and survival are changes in temperature and diminishing water supply. During acute temperature and water stress, plants often express stress proteins, such as dehydrins, which are intrinsically disordered hydrophilic
Externí odkaz:
https://doaj.org/article/e51400745d904ef6b5b3666244e3dec7
Publikováno v:
QRB Discovery, Vol 3 (2022)
α-Synuclein is a small neuronal protein that reversibly associates with lipid membranes. The membrane interactions are believed to be central to the healthy function of this protein involved in synaptic plasticity and neurotransmitter release. α-Sy
Externí odkaz:
https://doaj.org/article/e158eb16f848486c8328f53eac7c2e9f
Publikováno v:
JCIS Open, Vol 4, Iss , Pp 100024- (2021)
In this work we measured, by using a direct approach, the equilibrium solubility of recombinant Aβ40 peptide to be S = 0.36 ± 0.15 μM in aqueous solution of 20 mM sodium phosphate buffer at pH 7.4. Microfluidic diffusional sizing
Externí odkaz:
https://doaj.org/article/3570030016534ebd96291f8c2e153c7c
Autor:
Marija Dubackic, Ilaria Idini, Veronica Lattanzi, Yun Liu, Anne Martel, Ann Terry, Michael Haertlein, Juliette M. Devos, Andrew Jackson, Emma Sparr, Sara Linse, Ulf Olsson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The dense accumulation of α-Synuclein fibrils in neurons is considered to be strongly associated with Parkinson’s disease. These intracellular inclusions, called Lewy bodies, also contain significant amounts of lipids. To better understand such ac
Externí odkaz:
https://doaj.org/article/a70ac20dcd964258a94530f9bd60ccae
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8780 (2022)
In vivo, apolipoprotein A-I (ApoA-I) is commonly found together with lipids in so-called lipoprotein particles. The protein has also been associated with several diseases—such as atherosclerosis and amyloidosis—where insoluble aggregates containi
Externí odkaz:
https://doaj.org/article/6802633838bb4338a33c2879e0833ac6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
α-Synuclein is a membrane-interacting protein involved in Parkinson’s disease. Here we have investigated the co-association of α-synuclein and lipids from ganglioside-containing model membranes. Our study relies on the reported importance of gang
Externí odkaz:
https://doaj.org/article/b85da52212124afda9aba43ab192d4cf
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Amyloids are implicated in many diseases, and disruption of lipid membrane structures is considered as one possible mechanism of pathology. In this paper we investigate interactions between an aggregating peptide and phospholipid membranes, focusing
Externí odkaz:
https://doaj.org/article/09c28c90a6734d3d9b6cbbeac417e26e