Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emma Scull-Brown"'
Autor:
John Dingley, Satomi Okano, Richard Lee-Kelland, Emma Scull-Brown, Marianne Thoresen, Ela Chakkarapani
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0224447 (2020)
BackgroundTherapeutic hypothermia (TH) for 72h is the standard treatment following neonatal encephalopathy (NE). However, one-third do not benefit and adjunctive therapies are urgently needed. Xenon enhances neuroprotection with TH when administered
Externí odkaz:
https://doaj.org/article/7764e550cce54e459c28ce0b2c007c77
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
BackgroundOpioids like fentanyl are regularly used in neonates for analgesia and sedation. So far, they have been reported to be safe and eligible to use. The cerebellum has become a focus of neurodevelopmental research within the last years, as it i
Externí odkaz:
https://doaj.org/article/774b12d4bc4041dca87943a0721acafe
Autor:
Adam Frymoyer, Elavazhagan Chakkarapani, Julia Kristine Gundersen, Lars Walløe, David A. Menassa, Emma Scull-Brown, Marianne Thoresen, Sally Jary
Publikováno v:
EClinicalMedicine
Gundersen, J, Chakkarapani, E, Jary, S L, Menassa, D, Scull-Brown, E L, Frymoyer, A, Walløe, L & Thoresen, M 2021, ' Morphine and fentanyl exposure during therapeutic hypothermia does not impair neurodevelopment ', EClinicalMedicine, vol. 36, 100892 . https://doi.org/10.1016/j.eclinm.2021.100892
Gundersen, J, Chakkarapani, E, Jary, S L, Menassa, D, Scull-Brown, E L, Frymoyer, A, Walløe, L & Thoresen, M 2021, ' Morphine and fentanyl exposure during therapeutic hypothermia does not impair neurodevelopment ', EClinicalMedicine, vol. 36, 100892 . https://doi.org/10.1016/j.eclinm.2021.100892
BackgroundHypothermia-treated and intubated infants with moderate or severe hypoxic-ischemic encephalopathy (HIE) usually receive morphine for sedation and analgesia (SA) during therapeutic hypothermia (TH) and endotracheal ventilation. Altered drug
Autor:
Satomi Okano, Marianne Thoresen, Richard Lee-Kelland, Emma Scull-Brown, John Dingley, Elavazhagan Chakkarapani
Publikováno v:
Dingley, J, Okano, S, Lee-Kelland, R, Scull-Brown, E, Thoresen, M & Chakkarapani, E 2020, ' Closed-circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system : Development, technical evaluation and pulmonary effects ', PLoS ONE, vol. 15, no. 1 . https://doi.org/10.1371/journal.pone.0224447
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0224447 (2020)
PLoS ONE
PLoS ONE, Vol 15, Iss 1, p e0224447 (2020)
BackgroundTherapeutic hypothermia (TH) for 72h is the standard treatment following neonatal encephalopathy (NE). However, one-third do not benefit and adjunctive therapies are urgently needed. Xenon enhances neuroprotection with TH when administered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd501ec2736826611732181f353da28
https://hdl.handle.net/1983/6d6fabd6-8669-4b0b-8fc2-30176b4896f8
https://hdl.handle.net/1983/6d6fabd6-8669-4b0b-8fc2-30176b4896f8
Publikováno v:
Pediatric Research. 77:779-783
We previously reported that combining immediate hypothermia with immediate or 2 h delayed inhalation of an inert gas, xenon, gave additive neuroprotection in rats after a hypoxic-ischemic insult, compared to hypothermia alone. Defining the therapeuti
Autor:
Robert Keehan, Roberta Goodall, Oliver Beaumont, Akihiro Nishiguchi, Lizeth Lacharme-Lora, Michele Giugliano, Michiya Matsusaki, Christopher Coyle, Hiroyoshi Y. Tanaka, Tracey Masters, Nicki Cohen, Jon Hanley, Veronica H.L. Leinster, C. Patrick Case, Andrew D. Randall, Kristian Aquilina, Ian L. Sargent, Katja Simon, Nagaraj D. Halemani, Jennifer McGarvey, William Ind, Helena Kemp, Simon Grant, Emma Scull-Brown, Sharan Athwal, Aman Sood, Daniel J Curtis, Mitsuru Akashi, Rocco A Barone, Jon D. Lane, Thomas E. Phillips, Gavin Collett, Mitsunobu R. Kano, Leila Cornes, Xun Liu, Marianne Thoresen, Dionne Tannetta
Publikováno v:
Experimental neurology
Some psychiatric diseases in children and young adults are thought to originate from adverse exposures during fetal life, including hypoxia and hypoxia/reoxygenation. The mechanism is not understood. Several authors have emphasised that the placenta
Autor:
John Dingley, Emma Scull-Brown, Petter Andreas Steen, Marianne Thoresen, Xun Liu, Maja Elstad
Publikováno v:
Acta Anaesthesiologica Scandinavica. 57:646-653
Background Neuroprotection from therapeutic hypothermia increases when combined with the anaesthetic gas xenon in animal studies. A clinical feasibility study of the combined treatment has been successfully undertaken in asphyxiated human term newbor
Autor:
Emma Scull-Brown, Marianne Thoresen, Xun Liu, Elavazhagan Chakkarapani, John Dingley, James Tooley, Maja Elstad, Hemmen Sabir
BACKGROUND AND OBJECTIVES: Therapeutic hypothermia has become standard of care in newborns with moderate and severe neonatal encephalopathy; however, additional interventions are needed. In experimental models, breathing xenon gas during cooling offe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f046befad889105006103ac0b72c51
https://cronfa.swan.ac.uk/Record/cronfa27457
https://cronfa.swan.ac.uk/Record/cronfa27457
Publikováno v:
Stroke. 43(12)
Background and Purpose— Hypothermia (HT) for neonatal hypoxic-ischemic encephalopathy is advised to start within the first 6 hours after birth. There is some clinical evidence that HT is more effective against moderate than against severe hypoxic-i