Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emma S Rennel"'
Autor:
Emma S Rennel, Aize Kijlstra, Lukas J. A. G. Ricker, Alfons G.H. Kessels, Ellen C. La Heij, Fred Hendrikse, Tos T. J. M. Berendschot, Suzanne C. Dieudonné
Publikováno v:
Retina-The Journal of Retinal and Vitreous Diseases, 32(1), 54-59. LIPPINCOTT WILLIAMS & WILKINS
BACKGROUND In proliferative vitreoretinopathy (PVR), a nonangiogenic eye disease that is characterized by the formation of mainly avascular membranes, vascular endothelial growth factor (VEGF) levels are found to be upregulated. Recently, it was disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2285059d542de5d8142abf16f746bc
https://doi.org/10.1097/iae.0b013e31821800b9
https://doi.org/10.1097/iae.0b013e31821800b9
Autor:
Markus Thomas, David O. Bates, Steven J. Harper, Christian Klein, Emma S. Rennel, Jörg T. Regula
Publikováno v:
Microcirculation. 18:598-607
Please cite this paper as: Rennel, Regula, Harper, Thomas, Klein and Bates (2011). A Human Neutralizing Antibody Specific to Ang-2 Inhibits Ocular Angiogenesis. Microcirculation 18(7), 598–607. Abstract Objective: Angiogenesis, a critical contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6453dcc78218e75715898e58f7fb7509
https://doi.org/10.1111/j.1549-8719.2011.00120.x
https://doi.org/10.1111/j.1549-8719.2011.00120.x
Autor:
Coralie Hoareau-Aveilla, Elianna M. Amin, Michael Ladomery, Emma S. Rennel, Masatoshi Hagiwara, Steven J. Harper, Jeanette Woolard, David O. Bates, Dawid G. Nowak, Melissa V. Gammons, Gopinath Damodoran
Publikováno v:
The Journal of Biological Chemistry
Vascular endothelial growth factor (VEGF) is produced either as a pro-angiogenic or anti-angiogenic protein depending upon splice site choice in the terminal, eighth exon. Proximal splice site selection (PSS) in exon 8 generates pro-angiogenic isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c966f84b182196296d45053cb2e38b
http://europepmc.org/articles/PMC2820781
http://europepmc.org/articles/PMC2820781
Publikováno v:
Future Oncology. 5:703-712
Anti-angiogenic therapies currently revolve around targeting vascular endothelial growth factor-A (VEGF-A) or its receptors. These therapies are effective to some degree, but have low response rates and poor side-effect profiles. Part of these proble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1732ee4d20fe88ab5960ac9882b98203
https://doi.org/10.2217/fon.09.33
https://doi.org/10.2217/fon.09.33
Autor:
Y. Schüler, E. Waine, Hui Guan, Steven J. Harper, David Gillatt, Eugenie S. Kleinerman, Jeanette Woolard, Emma S. Rennel, David O. Bates, Marto Sugiono, William P.J. Leenders
Publikováno v:
British Journal of Cancer
British Journal of Cancer, 98, 7, pp. 1250-7
British Journal of Cancer, 98, 1250-7
British Journal of Cancer, 98, 7, pp. 1250-7
British Journal of Cancer, 98, 1250-7
Item does not contain fulltext Vascular endothelial growth factor-A is widely regarded as the principal stimulator of angiogenesis required for tumour growth. VEGF is generated as multiple isoforms of two families, the pro-angiogenic family generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::194327cfbc87f05cd16db661eb3b0335
https://doi.org/10.1038/sj.bjc.6604309
https://doi.org/10.1038/sj.bjc.6604309
Autor:
Sebastian Oltean, Gavin I. Welsh, Maryam Hamdollah-Zadeh, Melissa V. Gammons, Emma S. Rennel, Steven J. Harper, David O. Bates, Jing Hua, Michael Ladomery, Moin A. Saleem, Brigitte Royer-Pokora, Kirsty E. Symonds, Elianna M. Amin, David R. Hinton, Masatoshi Hagiwara, Dawid G. Nowak, Valérie Schumacher, Satoru Kase, Man-Kim Cheung, Lan Ni
Angiogenesis is regulated by the balance of proangiogenic VEGF(165) and antiangiogenic VEGF(165)b splice isoforms. Mutations in WT1, the Wilms' tumor suppressor gene, suppress VEGF(165)b and cause abnormal gonadogenesis, renal failure, and Wilms' tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad5a5a35c80a3f272676d2ff3b9e0ac8
https://europepmc.org/articles/PMC3574979/
https://europepmc.org/articles/PMC3574979/
Autor:
Emma S, Rennel, Jörg T, Regula, Steven J, Harper, Markus, Thomas, Christian, Klein, David O, Bates
Publikováno v:
Microcirculation (New York, N.Y. : 1994). 18(7)
Angiogenesis, a critical contributor to ocular as well as neoplastic diseases, is stimulated by endothelial production of angiopoietin-2 (Ang2). Our objective was to determine the requirement of ocular angiogenesis for Ang2 in animal models of diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfc12fa4f42bdfa59046c30db97ef1eb
https://pubmed.ncbi.nlm.nih.gov/21851472
https://pubmed.ncbi.nlm.nih.gov/21851472
Autor:
Hansjürgen Agostini, Bernd Junker, Lutz L. Hansen, Gottfried Martin, Nicolas Feltgen, Amelie Pielen, Andreas Stahl, Daniel Michels, Emma S. Rennel, Christoph Ehlken, Bastian Grundel
Publikováno v:
American journal of ophthalmology. 152(2)
Purpose To determine the concentration of the pro-angiogenic vascular endothelial growth factor VEGF 165 (VEGF) and the anti-angiogenic VEGF 165b in vitreous samples of patients with branch retinal vein occlusion (BRVO) and central retinal vein occlu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62153d8c5cb368c0a389103d65509a3d
https://pubmed.ncbi.nlm.nih.gov/21621189
https://pubmed.ncbi.nlm.nih.gov/21621189
Autor:
Christine Spee, Jing Hua, Steven J. Harper, Yan Qiu, Satoru Kase, Emma S. Rennel, David R. Hinton, Anette L. Magnussen, Amanda J. Churchill, Alexander H. R. Varey, David O. Bates, Sandeep Dhayade
Publikováno v:
Investigative ophthalmologyvisual science. 51(8)
Vascular endothelial growth factor (VEGF-A) is the principal stimulator of angiogenesis in wet age-related macular degeneration (AMD). However, VEGF-A is generated by alternate splicing into two families, the proangiogenic VEGF-A(xxx) family and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96b1d82895055df1298a768f6d136941
https://pubmed.ncbi.nlm.nih.gov/20237252
https://pubmed.ncbi.nlm.nih.gov/20237252
Autor:
David O. Bates, ER Wheatley, Ahr Varey, Emma S. Rennel, Amanda J. Churchill, Steven J. Harper, Lorna M. Stewart, Stephen J. Mather
Publikováno v:
British Journal of Cancer
The advent of anti-neovascular therapies in cancer and eye disease has prompted a burgeoning interest in the mechanisms behind the initiation, development and refinement of new vessel formation. The growth of new vessels from those already establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0143eebd181452c7fc708fe2d5d9973a
https://pubmed.ncbi.nlm.nih.gov/19707198
https://pubmed.ncbi.nlm.nih.gov/19707198