Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emma S, Holt"'
Autor:
Elizabeth A. Pekarskaya, Emma S. Holt, Jay A. Gingrich, Mark S. Ansorge, Jonathan A. Javitch, Sarah E. Canetta
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Depression and anxiety, two of the most common mental health disorders, share common symptoms and treatments. Most pharmacological agents available to treat these disorders target monoamine systems. Currently, finding the most effective trea
Externí odkaz:
https://doaj.org/article/dacd9ec969a649caa396d38a5bf9a485
Autor:
Sarah E Canetta, Emma S Holt, Laura J Benoit, Eric Teboul, Gabriella M Sahyoun, R Todd Ogden, Alexander Z Harris, Christoph Kellendonk
Publikováno v:
eLife, Vol 11 (2022)
In their seminal findings, Hubel and Wiesel identified sensitive periods in which experience can exert lasting effects on adult visual cortical functioning and behavior via transient changes in neuronal activity during development. Whether comparable
Externí odkaz:
https://doaj.org/article/6ec9213bdee04c83880c62f557c7c5bd
Autor:
Daniel C. Lowes, Linda A. Chamberlin, Lisa N. Kretsge, Emma S. Holt, Atheir I. Abbas, Alan J. Park, Lyubov Yusufova, Zachary H. Bretton, Ayesha Firdous, Armen G. Enikolopov, Joshua A. Gordon, Alexander Z. Harris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Acute stress transiently disrupts reward-seeking behaviour and repeated stress exposure produces lasting anhedonia-like behaviour in rodents. Here, the authors show that stress triggers GABAergic activity in the ventral tegmental area which blunts re
Externí odkaz:
https://doaj.org/article/00c4ef5a5a704504b5b5820961797043
Autor:
Sarah E Canetta, Emma S Holt, Laura J Benoit, Eric Teboul, Gabriella M Sahyoun, R Todd Ogden, Alexander Z Harris, Christoph Kellendonk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961c84b495611f27b82d97c8065cc071
https://doi.org/10.7554/elife.80324.sa2
https://doi.org/10.7554/elife.80324.sa2
Autor:
Lyubov Yusufova, Ayesha Firdous, Daniel C. Lowes, Lisa N. Kretsge, Emma S Holt, Alexander Z. Harris, Alan J. Park, Linda A. Chamberlin, Joshua A. Gordon, Armen G. Enikolopov, Zachary H. Bretton, Atheir I. Abbas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Decreased pleasure-seeking (anhedonia) forms a core symptom of depression. Stressful experiences precipitate depression and disrupt reward-seeking, but it remains unclear how stress causes anhedonia. We recorded simultaneous neural activity across li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbe9e5155880de844b0ece62b65c026
https://doaj.org/article/00c4ef5a5a704504b5b5820961797043
https://doaj.org/article/00c4ef5a5a704504b5b5820961797043
Autor:
Laura J. Benoit, Emma S. Holt, Lorenzo Posani, Stefano Fusi, Alexander Z. Harris, Sarah Canetta, Christoph Kellendonk
Impaired cortical maturation is a postulated mechanism in the etiology of neurodevelopmental disorders, including schizophrenia. In sensory cortex, activity relayed by the thalamus during a postnatal sensitive period is essential for proper cortical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6458e2b65acffe4f6f4562f8d7d1d32
https://doi.org/10.21203/rs.3.rs-730508/v1
https://doi.org/10.21203/rs.3.rs-730508/v1
Autor:
Laura J, Benoit, Emma S, Holt, Lorenzo, Posani, Stefano, Fusi, Alexander Z, Harris, Sarah, Canetta, Christoph, Kellendonk
Publikováno v:
Nature neuroscience. 25(6)
Impaired cortical maturation is a postulated mechanism in the etiology of neurodevelopmental disorders, including schizophrenia. In the sensory cortex, activity relayed by the thalamus during a postnatal sensitive period is essential for proper corti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccbc18b6c5e235bd3343afb080e5ec28
https://pubmed.ncbi.nlm.nih.gov/35590075
https://pubmed.ncbi.nlm.nih.gov/35590075
Autor:
Neil L. Harrison, Joshua A. Gordon, Christoph Kellendonk, Sarah Canetta, Emma S Holt, Nancy Padilla-Coreano, Scott S. Bolkan, Eric Teboul
Publikováno v:
Cerebral Cortex Communications
The medial prefrontal cortex (mPFC) integrates inputs from multiple subcortical regions including the mediodorsal nucleus of the thalamus (MD) and the ventral hippocampus (vHPC). How the mPFC differentially processes these inputs is not known. One po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f695f932508b3d7136012b3dea424b1
http://europepmc.org/articles/PMC7750130
http://europepmc.org/articles/PMC7750130
Autor:
Kretsge Ln, Daniel C. Lowes, Alan J. Park, Zachary H. Bretton, Chamberlin La, Yusufova L, Emma S Holt, Alexander Z. Harris, Firdous A, Atheir I. Abbas, Joshua A. Gordon
Stressful experiences frequently precede depressive episodes1. Depression results in anhedonia, or disrupted reward-seeking, in most patients2. In humans3,4 and rodents5,6, stress can disrupt reward-seeking, providing a potential mechanism by which s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f6516cea0837112482ad01450796a9
https://doi.org/10.1101/2020.05.28.121905
https://doi.org/10.1101/2020.05.28.121905
Autor:
Sarah E. Canetta, Christoph Kellendonk, Emma S Holt, Eric Teboul, Laura J Benoit, Joshua P Taliaferro
Publikováno v:
Behav Neurosci
Cognitive functions, such as working memory, are disrupted in most psychiatric disorders. Many of these processes are believed to depend on the medial prefrontal cortex (mPFC). Traditionally, maze-based behavioral tasks, which have a strong explorato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c538e1ebbc69d050b81b8f366869dd
https://europepmc.org/articles/PMC7289488/
https://europepmc.org/articles/PMC7289488/