Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Emma S, Chambers"'
Autor:
Emma S. Chambers, Weigang Cai, Giulia Vivaldi, David A. Jolliffe, Natalia Perdek, Wenhao Li, Sian E. Faustini, Joseph M. Gibbons, Corinna Pade, Alex G. Richter, Anna K. Coussens, Adrian R. Martineau
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract Vaccine development targeting SARS-CoV-2 in 2020 was of critical importance in reducing COVID-19 severity and mortality. In the U.K. during the initial roll-out most individuals either received two doses of Pfizer COVID-19 vaccine (BNT162b2)
Externí odkaz:
https://doaj.org/article/2bf8b9f303d3489cb53fdb91aa74388d
Autor:
David A. Jolliffe, Giulia Vivaldi, Emma S. Chambers, Weigang Cai, Wenhao Li, Sian E. Faustini, Joseph M. Gibbons, Corinna Pade, Anna K. Coussens, Alex G. Richter, Áine McKnight, Adrian R. Martineau
Publikováno v:
Nutrients, Vol 14, Iss 18, p 3821 (2022)
Vitamin D deficiency has been reported to associate with the impaired development of antigen-specific responses following vaccination. We aimed to determine whether vitamin D supplements might boost the immunogenicity and efficacy of SARS-CoV-2 vacci
Externí odkaz:
https://doaj.org/article/2ae76283f62140c58f05146a9d155c13
Autor:
Branca I. Pereira, Oliver P. Devine, Milica Vukmanovic-Stejic, Emma S. Chambers, Priya Subramanian, Neil Patel, Alex Virasami, Neil J. Sebire, Veronica Kinsler, Alexis Valdovinos, Claude Jourdan LeSaux, João F. Passos, Antony Antoniou, Malcom H. A. Rustin, Judith Campisi, Arne N. Akbar
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Senescent cells increase with ageing and may cause inflammatory conditions, but how this accumulation is mediated is still unclear. Here the authors show that senescent cells express HLA-E to suppress NKG2A-mediated natural killer and CD8 T cell acti
Externí odkaz:
https://doaj.org/article/a849def66981451db25ae5092d6b7804
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Vitamin D is synthesized in the skin following exposure to UVB radiation or is directly absorbed from the diet. Following hydroxylation in the liver and kidneys, vitamin D becomes its bioactive form, 1,25(OH)2D, which has been described to have poten
Externí odkaz:
https://doaj.org/article/e63fb9b5665b40f7a6dbbc82ba4013d9
Autor:
Giulia Vivaldi, David A Jolliffe, Sian Faustini, Adrian M Shields, Hayley Holt, Natalia Perdek, Mohammad Talaei, Florence Tydeman, Emma S Chambers, Weigang Cai, Wenhao Li, Joseph M Gibbons, Corinna Pade, Áine McKnight, Seif O Shaheen, Alex G Richter, Adrian R Martineau
Publikováno v:
The Journal of Infectious Diseases. 226:1903-1908
In this population-based cohort of 7538 adults, combined immunoglobulin (Ig) G, IgA, and IgM (IgG/A/M) anti-spike titers measured after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination were predictive of protection against bre
Autor:
Luciana P. Covre, Régia F. Martins, Oliver P. Devine, Emma S. Chambers, Milica Vukmanovic-Stejic, Juliana A. Silva, Reynaldo Dietze, Rodrigo R. Rodrigues, Herbert L. de Matos Guedes, Aloísio Falqueto, Arne N. Akbar, Daniel C. O. Gomes
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Leishmania (Viannia) braziliensis induces American tegumentary leishmaniasis that ranges in severity from the milder form, cutaneous (CL) to severe disseminated cutaneous leishmaniasis. Patients with CL develop a cell-mediated Th1 immune response acc
Externí odkaz:
https://doaj.org/article/1f35bdcc381541f580c4cd9e8b9f7e2f
Autor:
David A Jolliffe, Giulia Vivaldi, Emma S Chambers, Weigang Cai, Wenhao Li, Sian E Faustini, Joseph M Gibbons, Corinna Pade, Alex G Richter, Áine McKnight, Adrian R Martineau
SUMMARYBackground & AimsVitamin D deficiency has been reported to associate with impaired development of antigen-specific responses following vaccination. We aimed to determine whether vitamin D supplements might boost immunogenicity and efficacy of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce1469e0e773fca4e844e4daafac170a
https://doi.org/10.1101/2022.07.15.22277678
https://doi.org/10.1101/2022.07.15.22277678
Autor:
Emma S. Chambers, Roel P.H. De Maeyer
Publikováno v:
Immunology Letters. 230:1-10
Ageing is a global burden. Increasing age is associated with increased incidence of infections and cancer and decreased vaccine efficacy. This increased morbidity observed with age, is believed to be due in part to a decline in adaptive immunity, ter
Autor:
Neil A. Mabbott, Oliver P. Devine, Derek W. Gilroy, Milica Vukmanovic-Stejic, Emma S. Chambers, Barbara Shih, James Glanville, Tom C. Freeman, Arne N. Akbar, Malcolm H.A. Rustin, Priya Subramanian, Hugh Trahair
Publikováno v:
Chambers, E S, Vukmanovic-Stejic, M, Shih, B, Trahair, H, Subramanian, P, Devine, O P, Glanville, J, Gilroy, D W, Rustin, M, Freeman, T C, Mabbott, N & Akbar, A N 2021, ' Recruitment of inflammatory monocytes by senescent fibroblasts inhibits antigen-specific tissue immunity during human aging ', Nature Aging . https://doi.org/10.1038/s43587-020-00010-6
We have previously shown that healthy older adults exhibit reduced cutaneous immune responses during a varicella zoster virus (VZV) antigen challenge that correlated with a nonspecific inflammatory response to the injection itself. Here we found that
Autor:
Giulia Vivaldi, David A Jolliffe, Sian Faustini, Hayley Holt, Natalia Perdek, Mohammad Talaei, Florence Tydeman, Emma S Chambers, Weigang Cai, Wenhao Li, Joseph M Gibbons, Corinna Pade, Áine McKnight, Seif O Shaheen, Alex G Richter, Adrian R Martineau
In this population-based cohort of 7530 adults, combined IgG/A/M anti-Spike titres measured after SARS-CoV-2 vaccination were predictive of protection against breakthrough SARS-CoV-2 infection. Discrimination was significantly improved by adjustment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::972e5cdd2d43368299b371a678e590ba
https://doi.org/10.1101/2022.02.11.22270667
https://doi.org/10.1101/2022.02.11.22270667