Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emma R. Hoppe"'
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Supplementary Tables S1-S19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e51f56a5f32d341b5c2e51674ff765e
https://doi.org/10.1158/2643-3230.22543738
https://doi.org/10.1158/2643-3230.22543738
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Clonal hematopoiesis results from somatic mutations in cancer driver genes in hematopoietic stem cells. We sought to identify novel drivers of clonal expansion using an unbiased analysis of sequencing data from 84,683 persons and identified common mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55289da636eb1db4ca374a11330f8d09
https://doi.org/10.1158/2643-3230.c.6550390
https://doi.org/10.1158/2643-3230.c.6550390
Autor:
Benjamin L. Ebert, Siddhartha Jaiswal, Robert K. Bradley, Gad Getz, Chip Stewart, Elli Papaemmanuil, Luca Malcovati, Eva Hellstrom-Lindberg, Steven A. Carr, Kasper Lage, Donna S. Neuberg, Monkol Lek, Daniel G. MacArthur, Ruth Loos, Andrew D. Johnson, Michael H. Cho, Pinkal Desai, Bruce M. Psaty, Shankara Anand, Alex Barbera, Timothy Wood, Amaro Taylor-Weiner, Andrew Dunford, Abhishek Niroula, Mendy Miller, Joshua S. Weinstock, Alexander G. Bick, Björn Nilsson, Edyta Malolepsza, Benjamin Tanenbaum, Caroline Stanclift, Monica Schenone, Waihay Wong, Akansha Tarun, Marie McConkey, Cecilia A. Castellano, Anna Gallì, Maria Creignou, Gabriele Todisco, Emma R. Hoppe, Elsa Bernard, Matthew Leventhal, Ellen M. Beauchamp
Supplementary Figures S1-S11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08370a390f5261d6d0398c3791fc3597
https://doi.org/10.1158/2643-3230.22543741.v1
https://doi.org/10.1158/2643-3230.22543741.v1
Publikováno v:
Life Science Alliance. 6:e202201889
Recursive splicing is a non-canonical splicing mechanism in which an intron is removed in segments via multiple splicing reactions. Relatively few recursive splice sites have been identified with high confidence in human introns, and more comprehensi
Autor:
Emma R. Hoppe, Jacob T. Polaski, Jacqueline Watson, Robert K. Bradley, Joseph Pangallo, James D. Thomas, Alice H. Berger, Qing Feng, Naomi T. Nkinsi, Austin M. Gabel, Andrea E. Belleville, Emma De Neef, Maria McSharry
Publikováno v:
Nature genetics
While RNA-seq has enabled comprehensive quantification of alternative splicing, no correspondingly high-throughput assay exists for functionally interrogating individual isoforms. We describe pgFARM (paired guide RNAs for alternative exon removal), a
Autor:
Ruth J. F. Loos, Monkol Lek, Elli Papaemmanuil, Amaro Taylor-Weiner, Benjamin L. Ebert, Gad Getz, Björn Nilsson, Michael H. Cho, Elsa Bernard, Abhishek Niroula, Luca Malcovati, Monica Schenone, Pinkal Desai, Mendy Miller, Edyta Malolepsza, Daniel G. MacArthur, Joshua S. Weinstock, Waihay J. Wong, Anna Gallì, Kasper Lage, Marie McConkey, Maria Creignou, Andrew Dunford, Gabriele Todisco, Eva Hellström-Lindberg, Bruce M. Psaty, Shankara Anand, Chip Stewart, Akansha Tarun, Andrew D. Johnson, Benjamin Tanenbaum, Ellen M. Beauchamp, Cecilia A. Castellano, Caroline Stanclift, Emma R. Hoppe, Alexander G. Bick, Matthew Leventhal, Timothy Wood, Siddhartha Jaiswal, Alex Barbera, Robert K. Bradley, Donna Neuberg, Steven A. Carr
Publikováno v:
Blood Cancer Discov
Clonal hematopoiesis results from somatic mutations in cancer driver genes in hematopoietic stem cells. We sought to identify novel drivers of clonal expansion using an unbiased analysis of sequencing data from 84,683 persons and identified common mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40bb605c62f97829ff9bfa78189dcc91
https://europepmc.org/articles/PMC8462124/
https://europepmc.org/articles/PMC8462124/
Autor:
Mark Chaisson, Jay Shendure, Melanie Sorensen, Christopher M. Hill, Zev N. Kronenberg, Fred H. Gage, Andy Wing Chun Pang, Shwetha C. Murali, Olivia S. Meyerson, Jason G. Underwood, Carl Baker, Kendra Hoekzema, Ruolan Qiu, Bradley J. Nelson, Katherine M. Munson, Susan K. Dutcher, Ahmet M. Denli, Wesley C. Warren, Stuart Cantsilieris, Archana Raja, Ernest T. Lam, Alex Hastie, Richard K. Wilson, Karen Clark, Benedict Paten, David Haussler, Tina A. Graves-Lindsay, Joyce V. Lee, Emma R. Hoppe, Alex A. Pollen, Mark Diekhans, Valerie A. Schneider, Nicola Lorusso, Robert S. Fulton, Fereydoun Hormozdiari, David Gordon, Mario Ventura, Evan E. Eichler, Anne Marie E. Welch, Joel Armstrong, Max L. Dougherty, PingHsun Hsieh, Han Cao, Ian T. Fiddes
Publikováno v:
Science (New York, N.Y.), vol 360, iss 6393
INTRODUCTION Understanding the genetic differences that make us human is a long-standing endeavor that requires the comprehensive discovery and comparison of all forms of genetic variation within great ape lineages. RATIONALE The varied quality and c