Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Emma Pirilä"'
Autor:
Emma Pirilä, Otto Väyrynen, Elias Sundquist, Kaisa Päkkilä, Pia Nyberg, Sini Nurmenniemi, Virve Pääkkönen, Paula Pesonen, Dan Dayan, Marilena Vered, Lars Uhlin-Hansen, Tuula Salo
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120895 (2015)
Oral tongue squamous cell carcinoma (OTSCC) has a high mortality rate and the incidence is rising worldwide. Despite advances in treatment, the disease lacks specific prognostic markers and treatment modality. The spreading of OTSCC is dependent on t
Externí odkaz:
https://doaj.org/article/ccbfe8429f35408ba82911f5d3d29321
Autor:
Alina Winkelmann, Esa Färkkilä, Kirsi H. Pietiläinen, Tuula Salo, Pirjo Åström, Aila Rissanen, Jaakko Kaprio, Timo Sorsa, Anneli Lauhio, Emma Pirilä, Taina Tervahartiala
Publikováno v:
European Journal of Clinical Investigation. 46:757-765
Backround Obesity has been recognized as a state of subclinical inflammation resulting in a loss of insulin receptors and decreased insulin sensitivity. We here studied in vivo the role of circulating matrix metaloproteinase-8 (MMP-8) among young hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126b5319171029d161e0c42e0721e333
https://doi.org/10.1111/eci.12649
https://doi.org/10.1111/eci.12649
Autor:
Maija Risteli, Tuula Salo, Pia Nyberg, Emma Pirilä, Meeri Sutinen, Ritva Heljasvaara, Ilkka Alahuhta, Suvi-Tuuli Vilen, Mari Aikio, Otto Väyrynen, Pirjo Åström
Publikováno v:
Experimental cell research. 376(1)
Pro-tumorigenic activities of matrix metalloproteinase (MMP) 9 have been linked to many cancers, but recently the tumour-suppressing role of MMP9 has also been elucidated. The multifaceted evidence on this subject prompted us to examine the role of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::006c268962bc5244b4d77345d3e985d0
https://pubmed.ncbi.nlm.nih.gov/30710501
https://pubmed.ncbi.nlm.nih.gov/30710501
Publikováno v:
Cancer Biology & Therapy. 8:2362-2370
Matrix metalloproteinases (MMPs), and especially membrane type-1 matrix metalloproteinase (MT1-MMP, MMP-14), play a role in cancer progression and can have a prognostic value. Various synthetic broad-spectrum MMP inhibitors have been developed but ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f867f71ae603404b16aa6334b0a3439
https://doi.org/10.4161/cbt.8.24.10139
https://doi.org/10.4161/cbt.8.24.10139
Autor:
Carole L. Wilson, Amy P. Schmidt, Nicola Ferri, Emma Pirilä, William C. Parks, Erika V. Valore, Tomas Ganz, Timo Sorsa
Publikováno v:
Journal of Biological Chemistry. 284:8301-8311
Proteolytic processing of defensins is a critical mode of posttranslational regulation of peptide activity. Because mouse alpha-defensin precursors are cleaved and activated by matrix metalloproteinase-7 (MMP-7), we determined if additional defensin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb83590eada45a43f9d86e4e5efeb7c
https://doi.org/10.1074/jbc.m809744200
https://doi.org/10.1074/jbc.m809744200
Autor:
Emma Pirilä, Timo Sorsa, Tuula Salo, M Lahtinen, Esa Läärä, H. Maklin, Jarkko T. Korpi, Saara Kantola, V Kervinen, Gareth J. Thomas, M. Ylipalosaari, Pirjo Åström, Anu Väänänen, Carlos López-Otín, Ari Ristimäki
Publikováno v:
British Journal of Cancer
Squamous cell carcinoma (SCC) of the tongue is the most common cancer in the oral cavity and has a high mortality rate. A total of 90 mobile tongue SCC samples were analysed for Bryne's malignancy scores, microvascular density, and thickness of the S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1072bacc8b3c129b1d4ba6ca0b1ec3
http://europepmc.org/articles/PMC2259187
http://europepmc.org/articles/PMC2259187
Autor:
Jaana Hagström, Tuula Salo, Heidi Kuula, Ana Gutiérrez-Fernández, Georgios E. Romanos, Emma Pirilä, Timo Sorsa, Marita Luomanen
Publikováno v:
Archives of Oral Biology. 53:175-186
Objective Aberrant matrix metalloproteinase (MMP) and human β-defensin (HBD) functions have been found in inflammatory diseases. The objectives of this study were to investigate the immunolocalisation, mRNA expression and molecular forms of MMP-25,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4246376b725aa1bb3f3cdd2dfbd8c812
https://doi.org/10.1016/j.archoralbio.2007.09.010
https://doi.org/10.1016/j.archoralbio.2007.09.010
Autor:
Pia Nyberg, Paula Pesonen, Lars Uhlin-Hansen, Marilena Vered, Sini Nurmenniemi, Tuula Salo, Kaisa Päkkilä, Emma Pirilä, Elias Sundquist, Dan Dayan, Virve Pääkkönen, Otto Väyrynen
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120895 (2015)
PLoS ONE
PLoS ONE
Oral tongue squamous cell carcinoma (OTSCC) has a high mortality rate and the incidence is rising worldwide. Despite advances in treatment, the disease lacks specific prognostic markers and treatment modality. The spreading of OTSCC is dependent on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9aaf53649f9cb330cf64e5edb06fa1c
http://europepmc.org/articles/PMC4374792?pdf=render
http://europepmc.org/articles/PMC4374792?pdf=render
Publikováno v:
Journal of Clinical Periodontology. 33:462-468
Our study aimed to examine the molecular forms and gingival crevicular fluid (GCF) levels of laminin-5 gamma2-chain in patients with different periodontal disease, and compare the effects of P.gingivalis trypsin-like proteinase on intact laminin-5 ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a1b6c54ab89ee1dd920ee35bb9f380
https://doi.org/10.1111/j.1600-051x.2006.00933.x
https://doi.org/10.1111/j.1600-051x.2006.00933.x
Autor:
Juho Suojanen, Tuula Salo, Timo Sorsa, Pia Heikkilä, Erkki Koivunen, Anu Väänänen, Emma Pirilä
Publikováno v:
International Journal of Cancer. 118:2202-2209
Matrix metalloproteinases (MMP-2 and MMP-9, or gelatinases) are involved in tongue SCC invasion, metastasis and angiogenesis. We have recently shown that a novel and selective hydrophobic cyclic CTTHWGFTLC (CTT1) peptide is inhibitor for MMP-2 and MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6bda1bea852e3d97f29c905135042c
https://doi.org/10.1002/ijc.21540
https://doi.org/10.1002/ijc.21540