Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Emma Perez-Costas"'
Autor:
Ene M. Enogela, Taylor Buchanan, Christy S. Carter, Ronit Elk, Shena B. Gazaway, Burel R. Goodin, Elizabeth A. Jackson, Raymond Jones, Richard E. Kennedy, Emma Perez-Costas, Lisa Zubkoff, Emily L. Zumbro, Alayne D. Markland, Thomas W. Buford
Publikováno v:
International Journal for Equity in Health, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Disability prevention and preservation of independence is crucial for successful aging of older adults. To date, relatively little is known regarding disparities in independent aging in a disadvantaged older adult population despite widely r
Externí odkaz:
https://doaj.org/article/45ecd9ba82c24f669f2faeff5c6fc611
Autor:
Matthew W Rice, Kristen L Smith, Rosalinda C Roberts, Emma Perez-Costas, Miguel Melendez-Ferro
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100054 (2014)
Perturbations in metabolism are a well-documented but complex facet of schizophrenia pathology. Optimal cellular performance requires the proper functioning of the electron transport chain, which is constituted by four enzymes located within the inne
Externí odkaz:
https://doaj.org/article/ef1c51ba654f459697e3acec39e2b16d
Autor:
Emma Perez-Costas, Johanna C Gandy, Miguel Melendez-Ferro, Rosalinda C Roberts, Gautam N Bijur
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8911 (2010)
Glycogen synthase kinase-3beta (GSK3beta) is highly abundant in the brain. Various biochemical analyses have indicated that GSK3beta is localized to different intracellular compartments within brain cells. However, ultrastructural visualization of th
Externí odkaz:
https://doaj.org/article/99d6d0785a2d4390b6cea18a72776489
Autor:
Johanna C. Gandy, Emma Perez-Costas, Joy K. Roche, Miguel Melendez-Ferro, Benoit Lechat, David Demedts, Rosalinda C. Roberts, Gautam N. Bijur, Fred Van Leuven, Herman Devijver
Publikováno v:
Synapse. 67:313-327
Glycogen synthase kinase-3β (GSK3β) activity has been previously linked to Alzheimer's disease (AD) by its phosphorylation of tau and activation by amyloid. GSK3β intracellular distribution is important in regulating its activity by restricting ac
Publikováno v:
Journal of Neuroscience Methods. 208:86-91
In the present study, we applied the principles of immunoblotting and light microscopy immunohistochemistry to develop a combined methodology that allows obtaining optical density data in films, as well as morphological and protein distribution data
Autor:
Rosalinda C. Roberts, Emma Perez-Costas, Johanna C. Gandy, Miguel Melendez-Ferro, Keri A. Barksdale, Gautam N. Bijur
Publikováno v:
The FASEB Journal. 24:3590-3599
Neuronal function in the brain requires energy in the form of ATP, and mitochondria are canonically associated with ATP production in neurons. The electrochemical gradient, which underlies the mitochondrial transmembrane potential (ΔΨmem), is harne
Autor:
Begoña Villar-Cheda, Miguel Melendez-Ferro, Ramón Anadón, Emma Perez-Costas, María Celina Rodicio, Xesús M. Abalo
Publikováno v:
Journal of Chemical Neuroanatomy. 34:29-46
Lampreys belong to the most primitive extant group of vertebrates, the Agnathans, which is considered the sister group of jawed vertebrates. Accordingly, characterization of neuronal groups and their development appears useful for understanding early
Publikováno v:
BMC Neuroscience
Background Reelin expression and function have been extensively studied in the brain, although its expression has been also reported in other tissues including blood. This raises the possibility that reelin might be able to cross the blood-brain barr
Autor:
Ana Martínez, Eleonore Beurel, Emma Perez-Costas, Richard S. Jope, Miguel Melendez-Ferro, Margaret K. King, Marta Pardo
Publikováno v:
Frontiers in Behavioral Neuroscience
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Behavioral Neuroscience, Vol 9 (2015)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Frontiers in Behavioral Neuroscience, Vol 9 (2015)
12 p.-6 fig.
Brain glycogen synthase kinase-3 (GSK3) is hyperactive in several neurological conditions that involve impairments in both cognition and neurogenesis. This raises the hypotheses that hyperactive GSK3 may directly contribute to impai
Brain glycogen synthase kinase-3 (GSK3) is hyperactive in several neurological conditions that involve impairments in both cognition and neurogenesis. This raises the hypotheses that hyperactive GSK3 may directly contribute to impai
Autor:
Emma Perez-Costas, Miguel Melendez-Ferro, Verona Villar-Cerviño, Begoña Villar-Cheda, Xesús M. Abalo, M. Celina Rodicio, Ramón Anadón
Publikováno v:
Brain Research Bulletin. 66:536-540
We studied the organization of the dorsal column nucleus (DCN) of larval sea lamprey with immunohistochemical and tract-tracing techniques. Texas red-coupled dextran amine was injected into the spinal cord, which allowed tracing the dorsal column fib