Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis

Autor: Matteo Massara, Bastien Dolfi, Vladimir Wischnewski, Emma Nolan, Werner Held, Ilaria Malanchi, Johanna A. Joyce

Publikováno v: iScience, Vol 27, Iss 7, Pp 110284- (2024)

Summary: Brain metastases are the most common brain tumors in patients and are associated with poor prognosis. Investigating the colonization and outgrowth of brain metastases is challenging given the complexity of the organ, tissue sampling difficul

Externí odkaz: https://doaj.org/article/da5428f9bf474c7dbe061ce7a1009de5

Shared Decision‐Making During Virtual Care Regarding Rheumatologic and Chronic Conditions: Qualitative Study of Benefits, Pitfalls, and Optimization

Autor: Lisa Zickuhr, Catherine McCarthy, Emma Nolan‐Thomas, Tiffany Westrich‐Robertson, Elizabeth A. Baker, Janice L. Hanson

Publikováno v: ACR Open Rheumatology, Vol 6, Iss 1, Pp 32-42 (2024)

Objective Virtual care (VC) is an accepted modality of care delivery, and shared decision‐making (SDM) benefits patients with rheumatologic and chronic conditions (RCCs). Unfortunately, research suggests reduced quality of SDM during VC. This study

Externí odkaz: https://doaj.org/article/111c5085a3bb4830b236097f27980358

CD38 knockout natural killer cells expressing an affinity optimized CD38 chimeric antigen receptor successfully target acute myeloid leukemia with reduced effector cell fratricide

Autor: Mark Gurney, Arwen Stikvoort, Emma Nolan, Lucy Kirkham-McCarthy, Stanislav Khoruzhenko, Rama Shivakumar, Sonja Zweegman, Niels W.C.J. van de Donk, Tuna Mutis, Eva Szegezdi, Subhashis Sarkar, Michael O’Dwyer

Publikováno v: Haematologica, Vol 107, Iss 2 (2020)

There is a strong biological rationale for the augmentation of allogeneic natural killer (NK) cell therapies with a chimeric antigen receptor (CAR) to enhance acute myeloid leukemia (AML) targeting. CD38 is an established immunotherapeutic target in

Externí odkaz: https://doaj.org/article/b0166d6551d14cd29eee673fac8c0c91

Nutrient deficiency profiles and depression: A latent class analysis study of American population

Autor: Marcin Owczarek, Joanna Jurek, Emma Nolan, Mark Shevlin

Publikováno v: Journal of Affective Disorders. 317:339-346

Research into the effects of nutrition on depression is often performed by examining the effects of singular nutrients and dietary styles (e.g.: vegan, Mediterranean). The present study is the first one to establish the effects of patterns of nutriti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d228c1f6ab836c86ac9b1a1484dadbe9
https://doi.org/10.1016/j.jad.2022.08.100

Prevalence and risk factors of mood and anxiety disorders in children and young people: Findings from the Northern Ireland Youth Wellbeing Survey

Autor: Lisa Bunting, Emma Nolan, Claire McCartan, Gavin Davidson, Anne Grant, Ciaran Mulholland, Dirk Schubotz, Orla McBride, Jamie Murphy, Mark Shevlin

Publikováno v: Bunting, L, Nolan, E, McCartan, C, Davidson, G, Grant, A, Mulholland, C, Schubotz, D, McBride, O, Murphy, J & Shevlin, M 2022, ' Prevalence and Risk Factors of Mood and Anxiety Disorders in Children and Young People: Findings from the Northern Ireland Youth Wellbeing Survey ', Clinical Child Psychology and Psychiatry, vol. 27, no. 3, pp. 686-700 . https://doi.org/10.1177/13591045221089841

Objective: This paper presents the key findings from the Northern Ireland Youth Wellbeing Prevalence Survey (NIYWS), specifically the prevalence of common mental health disorders and their association with personal, familial and socio-economic risk f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c310a2a769d373390d1842357fc2f0e2
https://doi.org/10.1177/13591045221089841