Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Emma Nimeús"'
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Correct preoperative estimation of the malignant extent is crucial for optimal planning of breast cancer surgery. The sensitivity of mammography is lower in dense breasts, and additional imaging techniques are sometimes warranted.
Externí odkaz:
https://doaj.org/article/d8bc72192e6f4661b8df391f035a3f06
Autor:
Ugo Chianese, Chiara Papulino, Eugenia Passaro, Tom MJ. Evers, Mehrad Babaei, Antonella Toraldo, Tommaso De Marchi, Emma Niméus, Vincenzo Carafa, Maria Maddalena Nicoletti, Nunzio Del Gaudio, Nunzia Iaccarino, Antonio Randazzo, Dante Rotili, Antonello Mai, Salvatore Cappabianca, Alireza Mashaghi, Fortunato Ciardiello, Lucia Altucci, Rosaria Benedetti
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101561- (2022)
Objective: Aberrant activity of androgen receptor (AR) is the primary cause underlying development and progression of prostate cancer (PCa) and castration-resistant PCa (CRPC). Androgen signaling regulates gene transcription and lipid metabolism, fac
Externí odkaz:
https://doaj.org/article/df67d4dd16fd48ec98c9149449174dcf
Autor:
Mattias Aine, Ceren Boyaci, Johan Hartman, Jari Häkkinen, Shamik Mitra, Ana Bosch Campos, Emma Nimeus, Anna Ehinger, Johan Vallon-Christersson, Åke Borg, Johan Staaf
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-19 (2021)
Abstract Background Breast cancer in young adults has been implicated with a worse outcome. Analyses of genomic traits associated with age have been heterogenous, likely because of an incomplete accounting for underlying molecular subtypes. We aimed
Externí odkaz:
https://doaj.org/article/4912f58ed9244a1e8245e5010d96291a
Autor:
Martin Sjöström, Cynthia Veenstra, Erik Holmberg, Per Karlsson, Fredrika Killander, Per Malmström, Emma Niméus, Mårten Fernö, Olle Stål
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2713-2726 (2020)
Experimental studies suggest that hepatocyte growth factor (HGF) and its transmembrane tyrosine kinase receptor, Met, in part also relying on Akt kinase activity, mediate radioresistance. We investigated the importance of these biomarkers for the ris
Externí odkaz:
https://doaj.org/article/efd64e9c664e42559b7651d5419d26bc
Autor:
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, Christel Reuterswärd, Anna Karlsson, Shamik Mitra, Emma Niméus, Karolina Holm, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Christer Larsson, Martin Malmberg, Lisa Rydén, Anna Ehinger, Niklas Loman, Anders Kvist, Hans Ehrencrona, Serena Nik-Zainal, Åke Borg, Johan Staaf
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
BRCA-deficient breast cancer is characterised by homologous recombination deficiency. Here, the authors show that hypermethylated BRCA1 phenotypically copies mutated BRCA1 in triple negative breast cancers.
Externí odkaz:
https://doaj.org/article/364ce59486504bf6a831a413fa23b595
Autor:
Kristina Åhsberg, Anna Gardfjell, Emma Nimeus, Rogvi Rasmussen, Catharina Behmer, Sophia Zackrisson, Lisa Ryden
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Objectives The aim of this feasibility study was to evaluate the added value of contrast-enhanced mammography (CEM) in preoperative staging of malignant breast lesions, beyond standard assessment with digital mammography and ultrasound, as a
Externí odkaz:
https://doaj.org/article/19324657639c4ee89ee5083d70a0160a
Autor:
Martin Sjöström, Johan Staaf, Patrik Edén, Fredrik Wärnberg, Jonas Bergh, Per Malmström, Mårten Fernö, Emma Niméus, Irma Fredriksson
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-13 (2018)
Abstract Background Adjuvant radiotherapy is the standard of care after breast-conserving surgery for primary breast cancer, despite a majority of patients being over- or under-treated. In contrast to adjuvant endocrine therapy and chemotherapy, no d
Externí odkaz:
https://doaj.org/article/ff2a63d745da4d41932390437e13265a
Autor:
Mattias Aine, Ceren Boyaci, Johan Hartman, Jari Häkkinen, Shamik Mitra, Ana Bosch Campos, Emma Nimeus, Anna Ehinger, Johan Vallon-Christersson, Åke Borg, Johan Staaf
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-2 (2021)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/3660aa64683849c0a47efc9eaf8c9b40
Autor:
Tatjana Sajic, Yansheng Liu, Eirini Arvaniti, Silvia Surinova, Evan G. Williams, Ralph Schiess, Ruth Hüttenhain, Atul Sethi, Sheng Pan, Teresa A. Brentnall, Ru Chen, Peter Blattmann, Betty Friedrich, Emma Niméus, Susanne Malander, Aurelius Omlin, Silke Gillessen, Manfred Claassen, Ruedi Aebersold
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2819-2831.e5 (2018)
Cancer is mostly incurable when diagnosed at a metastatic stage, making its early detection via blood proteins of immense clinical interest. Proteomic changes in tumor tissue may lead to changes detectable in the protein composition of circulating bl
Externí odkaz:
https://doaj.org/article/f69a33aae6bb4289a7cf96673277a7c8
Autor:
Moa Egelberg, Tommaso De Marchi, Gyula Pekar, Lena Tran, Pär‐Ola Bendahl, Axel Stenmark Tullberg, Erik Holmberg, Per Karlsson, Marianne Farnebo, Fredrika Killander, Emma Nimeús
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2029-2040 (2023)
Downregulation of the DNA repair protein WD40‐encoding RNA antisense to p53 (WRAP53) has been associated with radiotherapy resistance and reduced cancer survival. The aim of this study was to evaluate WRAP53 protein and RNA levels as prognostic and
Externí odkaz:
https://doaj.org/article/9f6a87e3a0fc4942be09a021d9f6b9ed