Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Emma Nimeús"'
Autor:
Tommaso De Marchi, Chun-Fui Lai, Georgia M. Simmons, Isabella Goldsbrough, Alison Harrod, Thai Lam, Lakjaya Buluwela, Sven Kjellström, Christian Brueffer, Lao H. Saal, Johan Malmström, Simak Ali, Emma Niméus
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Three quarters of all breast cancers express the estrogen receptor (ER, ESR1 gene), which promotes tumor growth and constitutes a direct target for endocrine therapies. ESR1 mutations have been implicated in therapy resistance in metastatic
Externí odkaz:
https://doaj.org/article/d1192d9df9934484a96a115d8dfd7398
Autor:
Ugo Chianese, Chiara Papulino, Eugenia Passaro, Tom MJ. Evers, Mehrad Babaei, Antonella Toraldo, Tommaso De Marchi, Emma Niméus, Vincenzo Carafa, Maria Maddalena Nicoletti, Nunzio Del Gaudio, Nunzia Iaccarino, Antonio Randazzo, Dante Rotili, Antonello Mai, Salvatore Cappabianca, Alireza Mashaghi, Fortunato Ciardiello, Lucia Altucci, Rosaria Benedetti
Publikováno v:
Molecular Metabolism, Vol 64, Iss , Pp 101561- (2022)
Objective: Aberrant activity of androgen receptor (AR) is the primary cause underlying development and progression of prostate cancer (PCa) and castration-resistant PCa (CRPC). Androgen signaling regulates gene transcription and lipid metabolism, fac
Externí odkaz:
https://doaj.org/article/df67d4dd16fd48ec98c9149449174dcf
Autor:
Martin Sjöström, Cynthia Veenstra, Erik Holmberg, Per Karlsson, Fredrika Killander, Per Malmström, Emma Niméus, Mårten Fernö, Olle Stål
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2713-2726 (2020)
Experimental studies suggest that hepatocyte growth factor (HGF) and its transmembrane tyrosine kinase receptor, Met, in part also relying on Akt kinase activity, mediate radioresistance. We investigated the importance of these biomarkers for the ris
Externí odkaz:
https://doaj.org/article/efd64e9c664e42559b7651d5419d26bc
Autor:
Dominik Glodzik, Ana Bosch, Johan Hartman, Mattias Aine, Johan Vallon-Christersson, Christel Reuterswärd, Anna Karlsson, Shamik Mitra, Emma Niméus, Karolina Holm, Jari Häkkinen, Cecilia Hegardt, Lao H. Saal, Christer Larsson, Martin Malmberg, Lisa Rydén, Anna Ehinger, Niklas Loman, Anders Kvist, Hans Ehrencrona, Serena Nik-Zainal, Åke Borg, Johan Staaf
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
BRCA-deficient breast cancer is characterised by homologous recombination deficiency. Here, the authors show that hypermethylated BRCA1 phenotypically copies mutated BRCA1 in triple negative breast cancers.
Externí odkaz:
https://doaj.org/article/364ce59486504bf6a831a413fa23b595
Autor:
Kristina Åhsberg, Anna Gardfjell, Emma Nimeus, Rogvi Rasmussen, Catharina Behmer, Sophia Zackrisson, Lisa Ryden
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Objectives The aim of this feasibility study was to evaluate the added value of contrast-enhanced mammography (CEM) in preoperative staging of malignant breast lesions, beyond standard assessment with digital mammography and ultrasound, as a
Externí odkaz:
https://doaj.org/article/19324657639c4ee89ee5083d70a0160a
Autor:
Tatjana Sajic, Yansheng Liu, Eirini Arvaniti, Silvia Surinova, Evan G. Williams, Ralph Schiess, Ruth Hüttenhain, Atul Sethi, Sheng Pan, Teresa A. Brentnall, Ru Chen, Peter Blattmann, Betty Friedrich, Emma Niméus, Susanne Malander, Aurelius Omlin, Silke Gillessen, Manfred Claassen, Ruedi Aebersold
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2819-2831.e5 (2018)
Cancer is mostly incurable when diagnosed at a metastatic stage, making its early detection via blood proteins of immense clinical interest. Proteomic changes in tumor tissue may lead to changes detectable in the protein composition of circulating bl
Externí odkaz:
https://doaj.org/article/f69a33aae6bb4289a7cf96673277a7c8
Autor:
Moa Egelberg, Tommaso De Marchi, Gyula Pekar, Lena Tran, Pär‐Ola Bendahl, Axel Stenmark Tullberg, Erik Holmberg, Per Karlsson, Marianne Farnebo, Fredrika Killander, Emma Nimeús
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2029-2040 (2023)
Downregulation of the DNA repair protein WD40‐encoding RNA antisense to p53 (WRAP53) has been associated with radiotherapy resistance and reduced cancer survival. The aim of this study was to evaluate WRAP53 protein and RNA levels as prognostic and
Externí odkaz:
https://doaj.org/article/9f6a87e3a0fc4942be09a021d9f6b9ed
Autor:
Moa Egelberg, Tommaso De Marchi, Gyula Pekar, Lena Tran, Pär‐Ola Bendahl, Axel Stenmark Tullberg, Erik Holmberg, Per Karlsson, Marianne Farnebo, Fredrika Killander, Emma Nimeús
Publikováno v:
Molecular Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbeac14c4cf29318605c9fff1cfede20
https://doi.org/10.1002/1878-0261.13426
https://doi.org/10.1002/1878-0261.13426
Autor:
null Moa Egelberg, null Tommaso De Marchi, null Gyula Pekar, null Lena Tran, null Pär‐Ola Bendahl, null Axel Stenmark Tullberg, null Erik Holmberg, null Per Karlsson, null Marianne Farnebo, null Fredrika Killander, null Emma Nimeús
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ce6872785ec746c5b9cc7fd15d4af3
https://doi.org/10.1002/1878-0261.13426/v3/response1
https://doi.org/10.1002/1878-0261.13426/v3/response1
Autor:
Gudbjörg Sigurjonsdottir, Tommaso De Marchi, Anna Ehinger, Johan Hartman, Ana Bosch, Johan Staaf, Fredrika Killander, Emma Niméus
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background Immunohistochemical (IHC) PD-L1 expression is commonly employed as predictive biomarker for checkpoint inhibitors in triple-negative breast cancer (TNBC). However, IHC evaluation methods are non-uniform and further studies are nee
Externí odkaz:
https://doaj.org/article/a009212643f448b9bbced5c2d5101159