Výsledky vyhledávání - "Emma N. Cahill"

The bed nucleus of the stria terminalis in threat detection: task choice and rodent experience

Autor: Emily R. Sherman, Jasmine J. Thomas, Emma N. Cahill

Publikováno v: Emerging topics in life sciences.

Behavioural reactivity to potential threat is used to experimentally refine models of anxiety symptoms in rodents. We present a short review of the literature tying the most commonly used tasks to model anxiety symptoms to functional recruitment of b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3582ea68fdbf06940ccc0dc4d3745914
https://pubmed.ncbi.nlm.nih.gov/36416376

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Reactivity to conditioned threat cues is distinct from exploratory drive in the elevated plus-maze

Autor: Joe R. Hilton, Susannah R. Simpson, Emily R. Sherman, Will Raby‐Smith, Keemia Azvine, Maite Arribas, Jiaqi Zhou, Serena Deiana, Bastian Hengerer, Emma N. Cahill

Funder: Boehringer Ingelheim Pharma GmbH & Co. KG
Fear and anxiety are adaptive states that allow humans and animals alike to respond appropriately to threatening cues in their environment. Commonly used tasks for studying behaviour akin to fear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecb84b2e410e1a27566827a2a1fcc8c
https://doi.org/10.1101/2022.03.21.485161

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Targeting drug memory reconsolidation: a neural analysis

Autor: Uršulė Taujanskaitė, Emma N. Cahill, Amy L. Milton

Addiction can be conceptualised as a disorder of maladaptive learning and memory. Therefore, maladaptive drug memories supporting drug-seeking and relapse behaviours may present novel treatment targets for therapeutic approaches based upon reconsolid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfee8f26f10a72fc82f5019bd6823f94
https://www.repository.cam.ac.uk/handle/1810/308964

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Neurochemical and molecular mechanisms underlying the retrieval-extinction effect

Autor: Emma N. Cahill, Amy L. Milton

Publikováno v: Psychopharmacology

Extinction within the reconsolidation window, or 'retrieval-extinction', has received much research interest as a possible technique for targeting the reconsolidation of maladaptive memories with a behavioural intervention. However, it remains to be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493524113611fadfe222d60d066092aa

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D1R/GluN1 complexes in the striatum integrate dopamine and glutamate signalling to control synaptic plasticity and cocaine-induced responses

Autor: Christian Lüscher, Vincent Pascoli, Vincent Kappes, Emma N. Cahill, Peter Vanhoutte, D Savoldi, Jocelyne Caboche, Pierre Trifilieff

Publikováno v: Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2014, 19 (12), pp.1295-1304. ⟨10.1038/mp.2014.73⟩
Molecular psychiatry
Molecular Psychiatry, Vol. 19, No 12 (2014) P. 1295–1304
Molecular Psychiatry, 2014, 19 (12), pp.1295-1304. ⟨10.1038/mp.2014.73⟩

Convergent dopamine and glutamate signalling onto the extracellular signal-regulated kinase (ERK) pathway in medium spiny neurons (MSNs) of the striatum controls psychostimulant-initiated adaptive processes underlying long-lasting behavioural changes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4b46927913ad2c9c52dfc60d5c33f4
https://doi.org/10.1038/mp.2014.73

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Extracellular Signal-Regulated Protein Kinases 1 and 2 Activation by Addictive Drugs: A Signal Toward Pathological Adaptation

Autor: Jocelyne Caboche, Vincent Pascoli, Frank Bellivier, Peter Vanhoutte, Emma N. Cahill

Publikováno v: Biological Psychiatry
Biological Psychiatry, Elsevier, 2014, 76 (12), pp.917-926. ⟨10.1016/j.biopsych.2014.04.005⟩
Biological Psychiatry, 2014, 76 (12), pp.917-926. ⟨10.1016/j.biopsych.2014.04.005⟩

International audience; Addiction is a chronic and relapsing psychiatric disorder that is thought to occur in vulnerable individuals. Synaptic plasticity evoked by drugs of abuse in the so-called neuronal circuits of reward has been proposed to under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eda28ad1d2b01d5de005f2fa23543f9
https://hal.archives-ouvertes.fr/hal-01541326

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Convergence of dopamine and glutamate signaling onto striatal ERK activation in response to drugs of abuse

Autor: Jocelyne Caboche, Marine Salery, Emma N. Cahill, Peter Vanhoutte

Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Frontiers, 2014, 4, ⟨10.3389/fphar.2013.00172⟩
Frontiers in Pharmacology, 2014, 4, ⟨10.3389/fphar.2013.00172⟩
Frontiers in Pharmacology, Vol 4 (2014)
Frontiers in Pharmacology, 2014, 4, pp.UNSP 172. ⟨10.3389/fphar.2013.00172⟩
Frontiers in Pharmacology, Frontiers, 2014, 4, pp.UNSP 172. ⟨10.3389/fphar.2013.00172⟩

International audience; Despite their distinct targets, all addictive drugs commonly abused by humans evoke increases in dopamine (DA) concentration within the striatum. The main DA Guanine nucleotide binding protein couple receptors (GPCRs) expresse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a3c6faf931129e360fbb894cc09856
https://doi.org/10.3389/fphar.2013.00172

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