Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Emma M. Foster"'
Autor:
Emma M. Foster, Michael A. Waul, Paul M. Roberts, James E. Thomson, Ai M. Fletcher, James A. Lee, Stephen G. Davies
Publikováno v:
Tetrahedron. 70:7106-7119
A range of the methyl glycosides of 2-deoxy-2-aminohexoses, comprising d-allosamine, d-mannosamine, d-idosamine and d-talosamine, were prepared from the corresponding d-aldopentoses via a seven step synthetic sequence. The doubly diastereoselective c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a974e6e4619fe981de0536120f209072
https://doi.org/10.1016/j.tet.2014.06.019
https://doi.org/10.1016/j.tet.2014.06.019
The asymmetric syntheses of novel dihydroxyhomoprolines have been achieved using the doubly diastereoselective conjugate additions of the antipodes of lithium N-benzyl-N-(α-methylbenzyl)amide to a set of four chiral α,β-unsaturated esters (derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6a1027346a0057226a9c69214c8f661
https://doi.org/10.1016/j.tet.2013.07.096
https://doi.org/10.1016/j.tet.2013.07.096
Autor:
James A. Lee, Emma M. Foster, James E. Thomson, Ai M. Fletcher, Stephen G. Davies, Paul M. Roberts
Efficient asymmetric syntheses of APTO and AETD, the highly functionalized β-amino acid fragments within microsclerodermins C, D, and E, are reported. The conjugate addition of lithium (R)-N-benzyl-N-(α-methylbenzyl)amide to tert-butyl (E,E)-7-(tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f37666514a9f943f0af6b3c407ca55
https://ora.ox.ac.uk/objects/uuid:abbaeb3d-6832-45e3-b24e-1eabcae4ecfa
https://ora.ox.ac.uk/objects/uuid:abbaeb3d-6832-45e3-b24e-1eabcae4ecfa
Enantiopure ε-O-silyloxy- and ε-O-benzyloxy-α,β- unsaturated esters derived from d-ribose, each containing a cis-dioxolane unit, display excellent (≥95:5 dr) levels of diastereofacial directing ability upon conjugate addition of achiral lithium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ac58aafbac56c864abd6ac4de58f0f
https://doi.org/10.1016/j.tetasy.2014.02.004
https://doi.org/10.1016/j.tetasy.2014.02.004
Autor:
Catherine R. McIntosh, Stephen G. Davies, Paul M. Roberts, Timothy E. Rosser, James E. Thomson, Emma M. Foster, Andrew Smith
The conjugate addition of lithium (S)-N-benzyl-N-(α-methylbenzyl) amide to a range of aryl substituted tert-butyl cinnamate esters followed by reaction of the resultant lithium β-amino enolates with D2O provides access to anti configured α-deuteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267f54ada77bc5be1201ec8ae2b7d6d1
https://ora.ox.ac.uk/objects/uuid:6ebaaa5f-dafb-4c93-8285-ede66b5051d2
https://ora.ox.ac.uk/objects/uuid:6ebaaa5f-dafb-4c93-8285-ede66b5051d2
A range of biologically significant imino and amino sugars [1,4-dideoxy-1,4-imino-D-allitol, 3,6-dideoxy-3,6-imino-L-allonic acid, (3R,4S)-3,4-dihydroxy-L-proline, 1,5-anhydro-4-deoxy-4-amino-D-glucitol, and 1,5-anhydro-4-deoxy-4-amino-L-iditol] has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c69ef6d5a99d0a24962693f824fe98
https://doi.org/10.1021/jo5018298
https://doi.org/10.1021/jo5018298
Autor:
Stephen G. Davies, Thomas M. Schofield, Paul M. Roberts, Ai M. Fletcher, Emma M. Foster, James E. Thomson, Ian T. T. Houlsby
Publikováno v:
ChemInform. 46
Eight-step syntheses of (-)-lupinine (Ia), (+)-isoretronecanol (Ib), (+)-5-epi-tashiromine (Ic) and (R,R)-1-(hydroxymethyl)octahydroindolizine (Id), which is part of stelletamides A-C, are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef218f6729818af00f863cc9f357e32
https://doi.org/10.1002/chin.201517268
https://doi.org/10.1002/chin.201517268
Autor:
Emma M. Foster, Paul M. Roberts, Stephen G. Davies, Michael A. Waul, James E. Thomson, James A. Lee, Ai M. Fletcher
Publikováno v:
ChemInform. 46
As is demonstrated for the D-allosamine presursor (VI), the approach to the title compounds includes the auxiliary (II) and the oxidant CSO in the stereodefining key step.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0de90bcd6d9098a5cdabd329da321a64
https://doi.org/10.1002/chin.201510265
https://doi.org/10.1002/chin.201510265
Autor:
Thomas M. Schofield, James E. Thomson, Stephen G. Davies, Ai M. Fletcher, Ian T. T. Houlsby, Emma M. Foster, Paul M. Roberts
Publikováno v:
ChemInform. 45
The asymmetric synthesis of (−)-lupinine was achieved in 8 steps, 15% overall yield and >99:1 dr from commercially available starting materials. The strategy used for the construction of the quinolizidine scaffold involved reaction of an enantiopur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3c240f0b054d0a0817a5730255490e4
https://doi.org/10.1002/chin.201452202
https://doi.org/10.1002/chin.201452202
Autor:
Emma M. Foster, James E. Thomson, Ian T. T. Houlsby, Ai M. Fletcher, Paul M. Roberts, Stephen G. Davies, Thomas M. Schofield
Publikováno v:
Organicbiomolecular chemistry. 12(45)
Concise asymmetric syntheses of (-)-lupinine, (+)-isoretronecanol, (+)-5-epi-tashiromine and (R,R)-1-(hydroxymethyl)octahydroindolizine (the azabicyclic core within stellettamides A-C) have been achieved in 8 steps or fewer from commercially availabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a603a82066140ec08de9fecd3f7579c
https://pubmed.ncbi.nlm.nih.gov/25300749
https://pubmed.ncbi.nlm.nih.gov/25300749