Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emma M Garcia"'
Autor:
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Publikováno v:
eLife, Vol 12 (2023)
Allostery enables dynamic control of protein function. A paradigmatic example is the tightly orchestrated process of DNA methylation maintenance. Despite the fundamental importance of allosteric sites, their identification remains highly challenging.
Externí odkaz:
https://doaj.org/article/77dc5b6fa55344c28ec05a1bf2d5c339
Publikováno v:
Nature Chemical Biology. 19:176-186
Autor:
Emma M. Garcia, Nicholas Z. Lue, Jessica K. Liang, Whitney K. Lieberman, Derek D. Hwang, James Woods, Brian B. Liau
DNA methyltransferase 3A (DNMT3A) is ade novocytosine methyltransferase responsible for establishing proper DNA methylation during mammalian development. Loss-of-function (LOF) mutations to DNMT3A, including the hotspot mutation R882H, frequently occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbef8a35fd944d3eb9bc01fa861bf4be
https://doi.org/10.1101/2023.04.12.536656
https://doi.org/10.1101/2023.04.12.536656
Autor:
Kevin Chun-Ho Ngan, Samuel M Hoenig, Hui Si Kwok, Nicholas Z Lue, Pallavi M Gosavi, David A Tanner, Emma M Garcia, Ceejay Lee, Brian B Liau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af23885b076db27413b07fe53044042
https://doi.org/10.7554/elife.80640.sa2
https://doi.org/10.7554/elife.80640.sa2
Autor:
Emma M. Garcia, Nicholas Z. Lue, Keith Rivera, Maya Virshup, Jessica K. Liang, Derek D. Hwang, Steven A. Carr, Brian B. Liau
Publikováno v:
Biophysical Journal. 122:352a
Autor:
Jeffery M. Tharp, Omer Ad, Kazuaki Amikura, Fred R. Ward, Emma M. Garcia, Jamie H. D. Cate, Alanna Schepartz, Dieter Söll
Publikováno v:
Angewandte Chemie. 132:3146-3150
Autor:
Emma M. Garcia, Fred R. Ward, Jeffery M. Tharp, Jamie H. D. Cate, Alanna Schepartz, Omer Ad, Kazuaki Amikura, Dieter Söll
Publikováno v:
Angewandte Chemie (International ed. in English). 59(8)
By transplanting identity elements into E. coli tRNAfMet , we have engineered an orthogonal initiator tRNA (itRNATy2 ) that is a substrate for Methanocaldococcus jannaschii TyrRS. We demonstrate that itRNATy2 can initiate translation in vivo with aro