Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emma Leire"'
Autor:
Ruth Plummer, Katy Newton, Emma Leire, Jen Middleton, Mariam Jamal-Hanjani, Eloise Williams, Samra Turajlic, Monica Sassi, Andrew Furness, Chloe Maine, Sergio A. Quezada, Fiona C Thistlethwaite, Matilde Saggese, Amy Baker, Judith Cave, Martin Forster, Michael Epstein, Michael M. Grant
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A572-A572
BackgroundEx-vivo expanded tumour infiltrating lymphocytes (TIL) show promise in delivering durable responses among several solid tumour indications. However, characterising, quantifying and tracking the active component of TIL therapy remains challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42ed55bb5443b01354c974220a5ebdfe
https://doi.org/10.1136/jitc-2021-sitc2021.543
https://doi.org/10.1136/jitc-2021-sitc2021.543
Autor:
Samra Turaljic, Karl S. Peggs, Mark Brown, Sergio A. Quezada, Amy Baker, Eva Pekle, Leah Manning, Mariam Jamal-Hanjani, Pablo D. Becker, Anabel Ramirez, Jane Robertson, Theres Oakes, Rebecca Pike, Iraj Ali, Emma Leire, Natasa Hadjistephanou, Daisy Melandri, Martin Forster, Megan Wileman, Lylia Ouboussad, Michael Epstein, Jen Middleton
Publikováno v:
Cancer Research. 81:1508-1508
Adoptive cell therapy (ACT) using ex vivo expanded tumor infiltrating lymphocytes (TIL) has shown great promise as a treatment for metastatic melanoma and has the potential to deliver durable responses in other solid tumors. Clonal neoantigens, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9d5968615d74415db441336dc137cd9
https://doi.org/10.1158/1538-7445.am2021-1508
https://doi.org/10.1158/1538-7445.am2021-1508
Autor:
Charles Edward Selkirk Roberts, Sascha A. Kristian, Emma Leire, Bradley Hall, Kary B. Mullis, Robert Old, Uri Galili, John Iacomini, Victor Nizet, John H. Hwang, Mike Westby
Publikováno v:
Journal of Molecular Medicine. 93:619-631
The ever-increasing threat of multi-drug resistant bacterial infections has spurred renewed interest in alternative approaches to classical antibiotic therapy. In contrast to other mammals, humans do not express the galactose-α-1,3-galactosyl-β-1,4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e4c18c47d7c949b60d24012e930b91
https://doi.org/10.1007/s00109-015-1280-4
https://doi.org/10.1007/s00109-015-1280-4
Autor:
Vishal Patel, Thomas F. Gallegos, Andrew Hollands, Roman Sasik, Gary Hardiman, Victor Nizet, Salah A. Mohamed, Vishal Nigam, Charles C. King, Andrew Hinton, Katrina Carrion, Jeffrey Dyo, Emma Leire, Sanjay K. Nigam
Publikováno v:
The FASEB Journal. 29:1859-1868
Bicuspid aortic valves calcify at a significantly higher rate than normal aortic valves, a process that involves increased inflammation. Because we have previously found that bicuspid aortic valve experience greater stretch, we investigated the poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53cc537f65283e75b0abdf7d223221ab
https://doi.org/10.1096/fj.14-257808
https://doi.org/10.1096/fj.14-257808
Autor:
Eduardo Fernandez-Megia, Emma Leire, Sandra P. Amaral, Iria Louzao, Klaus Winzer, Francisco Fernandez-Trillo, Cameron Alexander
Publikováno v:
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
instname
Here, we evaluate how cationic gallic acid-triethylene glycol (GATG) dendrimers interact with bacteria and their potential to develop new antimicrobials. We demonstrate that GATG dendrimers functionalised with primary amines in their periphery can in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63083a53a9a5bf5cd8ccdbf665133ea
https://hdl.handle.net/10347/16977
https://hdl.handle.net/10347/16977
Publikováno v:
Leire, Emma; Olson, Josh; Isaacs, Hart; Nizet, Victor; & Hollands, Andrew. (2013). Role of hypoxia inducible factor-1 in keratinocyte inflammatory response and neutrophil recruitment. Journal of Inflammation, 10(1), 28. doi: http://dx.doi.org/10.1186/1476-9255-10-28. Retrieved from: http://www.escholarship.org/uc/item/9dj5b251
Journal of Inflammation (London, England)
Journal of Inflammation (London, England)
Background Hypoxia inducible factor-1 (HIF-1) is a major regulator of the cellular adaption to low oxygen stress and the innate immune function of myeloid cells. Treatment with the novel HIF-1 stabilizing drug AKB-4924 has been shown to enhance the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cafdb782556823bb83fd4094c5df82
https://doi.org/10.1186/1476-9255-10-28
https://doi.org/10.1186/1476-9255-10-28
Autor:
Victor Nizet, Andrew Hollands, Richard L. Gallo, Pieter C. Dorrestein, Cortny A. Donald, David Gonzalez, Martina L. Sanderson-Smith, Emma Leire
Publikováno v:
The Journal of biological chemistry. 287(49)
The bacterial pathogen Group A Streptococcus (GAS) colonizes epithelial and mucosal surfaces and can cause a broad spectrum of human disease. Through the secreted plasminogen activator streptokinase (Ska), GAS activates human plasminogen into plasmin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bade3b93f65e063ec9001711c96fe9
https://pubmed.ncbi.nlm.nih.gov/23038245
https://pubmed.ncbi.nlm.nih.gov/23038245