Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Emma Leena Alarmo"'
Autor:
Sanna Penkki, Johanna Ketolainen, Riikka Havunen, Matti Nykter, Anne Kallioniemi, Sergei Häyrynen, Emma-Leena Alarmo
Publikováno v:
Genes, Chromosomes and Cancer. 55:227-236
Bone morphogenetic protein 4 (BMP4) is a remarkably powerful inhibitor of breast cancer cell proliferation, but it is also able to induce breast cancer cell migration in certain cellular contexts. Previous data demonstrate that BMP4 controls the tran
Autor:
Kaija Holli, Emma-Leena Alarmo, Seppo Parkkila, Liisa Pylkkänen, Tarja Korhonen, Heini Huhtala, Tuula Kuukasjärvi, Anne Kallioniemi
Publikováno v:
Modern Pathology. 26(1):10-21
Bone morphogenetic proteins (BMPs) are extracellular signaling molecules that belong to the transforming growth factor β (TGFβ) superfamily and are known to regulate cell proliferation, differentiation and motility, especially during development. B
Autor:
Riikka Havunen, Harold L. Moses, Anne Kallioniemi, Agnieszka E. Gorska, Minna Ampuja, Philip Owens, Emma-Leena Alarmo
Publikováno v:
Cancer letters. 375(2)
Bone morphogenetic protein 4 (BMP4) is a key regulator of cell proliferation and differentiation. In breast cancer cells, BMP4 has been shown to reduce proliferation in vitro and interestingly, in some cases, also to induce migration and invasion. He
Publikováno v:
Experimental Cell Research. 317:2136-2146
Bone morphogenetic proteins (BMPs) are multifunctional signaling molecules that have gained increasing interest in cancer research. To obtain a systematic view on BMP signaling in pancreatic cancer we first determined the mRNA expression levels of se
Autor:
Emma-Leena, Alarmo, Riikka, Havunen, Sergei, Häyrynen, Sanna, Penkki, Johanna, Ketolainen, Matti, Nykter, Anne, Kallioniemi
Publikováno v:
Genes, chromosomescancer. 55(3)
Bone morphogenetic protein 4 (BMP4) is a remarkably powerful inhibitor of breast cancer cell proliferation, but it is also able to induce breast cancer cell migration in certain cellular contexts. Previous data demonstrate that BMP4 controls the tran
Publikováno v:
Breast Cancer Research and Treatment. 103:239-246
Bone morphogenetic proteins (BMPs) regulate diverse cellular processes, such as proliferation, differentiation, and apoptosis. The BMPs have been studied in several cancers, but thus far contradictory results have been obtained and, especially in bre
Autor:
Ritva Karhu, Emma-Leena Alarmo, Tuula Kuukasjärvi, Jenita Rauta, Anne Kallioniemi, Päivikki Kauraniemi
Publikováno v:
Genes, Chromosomes and Cancer. 45:411-419
Bone morphogenetic proteins (BMP) make up a family of extracellular signaling molecules that play a critical role in vertebrate development and both inhibit and stimulate growth in cancer cells. BMP7 was recently identified in our genomewide copy num
Autor:
Anne Kallioniemi, Ritva Karhu, Tuula Kuukasjärvi, Päivikki Kauraniemi, Emma-Leena Alarmo, Jenita Rauta
Publikováno v:
Breast Cancer Research and Treatment. 95:257-263
The serine-threonine protein phosphatase PPM1D is likely to play an important role in tumorigenesis. Through inactivation of p38 MAPK, PPM1D acts as a negative feedback regulator of p53 tumour suppressor gene and controls the expression of other cell
Publikováno v:
International journal of clinical and experimental pathology. 6(7)
Gremlin 1 and noggin are inhibitors of bone morphogenetic protein (BMP) signaling. They are vital during early development but their role in adult tissues has remained largely unresolved. The BMP signaling pathway has also been implicated in tumorige
Autor:
Tuula Kuukasjärvi, Anne Kallioniemi, T. Korhonen, Heini Huhtala, Kaija Holli, Liisa Pylkkänen, Emma-Leena Alarmo
Publikováno v:
Breast (Edinburgh, Scotland). 22(6)
The aim of the study was to evaluate the long-term survival of patients with invasive lobular carcinomas (ILC) and invasive ductal carcinomas (IDC) and the metastatic behavior of these two disease entities. Originally, all consecutive patients with p