Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Emma Leacy"'
Autor:
Emma Leacy, Isabella Batten, Laetitia Sanelli, Matthew McElheron, Gareth Brady, Mark A. Little, Hania Khouri
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionImmunometabolism examines the links between immune cell function and metabolism. Dysregulation of immune cell metabolism is now an established feature of innate immune cell activation. Advances in liquid chromatography mass spectrometry (
Externí odkaz:
https://doaj.org/article/a83b49c5422a464a80cd95359831bb14
Autor:
Clíona Ní Cheallaigh, Laura O'Doherty, Nicole Wood, Stuart Hendricken Phelan, Jacklyn Sui, Sorcha O'Brien, Fergal Howley, Cian Mangan, Noor Adeebah Mohamed Razif, Siobhan O'Regan, Ruth Argue, Ciara Conlan, Adam Dyer, Samuel Holohan, Roman Romero-Ortuno, Liam Townsend, Fara Salleh, Colm Kerr, Gerard Hughes, Alberto Sanz, Derval Reidy, Andrea Kelly, Emma Connolly, Siobhan Gargan, Conor Reddy, Heike Hawerkamp, Eamon Breen, Ignacio Martin-Loeches, Jean Dunne, Aideen Long, Anne Marie McLaughlin, Padraic Fallon, Orla Shiels, Ciaran Bannan, Martina Hennessy, Ana Rakovac, Anna Rose Prior, Ross McManus, William McCormack, Colm Bergin, Seamus Donnelly, Mark Little, Emma Leacy, Niall Conlon
Publikováno v:
HRB Open Research, Vol 5 (2022)
Background: The current coronavirus disease 2019 (COVID-19) pandemic began in Ireland with the first confirmed positive case in March 2020. In the early stages of the pandemic clinicians and researchers in two affiliated Dublin hospitals identified t
Externí odkaz:
https://doaj.org/article/f3611967469d4829b773b45897958a77
Autor:
Eóin C. O'Brien, Carla A. White, Jason Wyse, Emma Leacy, Richard K. Porter, Mark A. Little, Fionnuala B. Hickey
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils has been extensively inves
Externí odkaz:
https://doaj.org/article/3f349d7f5626495b80d6cc89bae479b3
Autor:
Laura O'Doherty, Stuart Hendricken Phelan, Nicole Wood, Sorcha O'Brien, Jacklyn Sui, Cian Mangan, Fergal Howley, Siobhan O'Regan, Noor Adeebah Mohamed Razif, Ciara Conlan, Ruth Argue, Samuel Holohan, Adam Dyer, Fara Salleh, Liam Townsend, Gerard Hughes, Colm Kerr, Derval Reidy, Alberto Sanz, Emma Connolly, Andrea Kelly, Emma Leacy, Conor Reddy, Siobhan Gargan, Eamon Breen, Heike Hawerkamp, Jean Dunne, Ignacio Martin-Loeches, Anne Marie McLaughlin, Aideen Long, Orla Shiels, Padraic Fallon, Martina Hennessy, Roman Romero-Ortuno, Ciaran Bannan, Anna Rose Prior, Ana Rakovac, William McCormack, Ross McManus, Seamus Donnelly, Colm Bergin, Mark Little, Clíona Ní Cheallaigh, Niall Conlon
Publikováno v:
HRB open research. 5
Background: The current coronavirus disease 2019 (COVID-19) pandemic began in Ireland with the first confirmed positive case in March 2020. In the early stages of the pandemic clinicians and researchers in two affiliated Dublin hospitals identified t
Publikováno v:
Rheumatology. 59:iii33-iii41
ANCA-associated vasculitis (AAV) is a severe systemic autoimmune disease. A key feature of AAV is the presence of Anti-Neutrophil Cytoplasmic Antibodies (ANCA) directed against myeloperoxidase (MPO) or proteinase-3 (PR3). ANCA are key to the pathogen
Autor:
Claire L. Tonry, Emma Leacy, Cinzia Raso, Stephen P. Finn, John Armstrong, Stephen R. Pennington
Publikováno v:
Diagnostics, Vol 6, Iss 3, p 27 (2016)
Prostate Cancer (PCa) is the second most commonly diagnosed cancer in men worldwide. Although increased expression of prostate-specific antigen (PSA) is an effective indicator for the recurrence of PCa, its intended use as a screening marker for PCa
Externí odkaz:
https://doaj.org/article/1e07e6be902b4df5821b73973420ce0a
Autor:
Mark A. Little, Richard K. Porter, Fionnuala B. Hickey, Carla A White, Eóin C O'Brien, Emma Leacy, Jason Wyse
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils has been extensively inves
Publikováno v:
Rheumatology. 58
Autor:
Thomas Phelan, Michael R. Clarkson, Gareth Brady, Jennifer Scott, Declan O'Sullivan, Alyssa Verrelli, Matthew D. Griffin, Jean Dunne, Julie Power, Michelle O'Saughnessy, Emma Leacy, Lina Zgaga, Mark A. Little, Niall Conlon, William McCormack, Alan Kennedy, E. Molloy
Publikováno v:
HRB Open Research. 4:6
The ongoing coronavirus disease 2019 (COVID-19) pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Current advisory guidelines for high-risk groups—including people with autoimmune disease taking immunosuppressive t
Autor:
Thomas Mehrling, Gareth Brady, Eóin C O'Brien, Peter Heeringa, Fionnuala B. Hickey, Mark A. Little, Barbara Fazekas, Mirjan M. van Timmeren, Dearbhaile Dooley, Emma Leacy, Charles D. Pusey, Vincent P. O’Reilly, Frederick W.K. Tam
Publikováno v:
Kidney International, 94(5), 926-936. ELSEVIER SCIENCE INC
Current therapies for treating antineutrophil cytoplasm autoantibody (ANCA)-associated vasculitis include cyclophosphamide and corticosteroids. Unfortunately, these agents are associated with severe adverse effects, despite inducing remission in most