Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Emma Laporte"'
Autor:
Emma Laporte, Hugo Vankelecom
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The pituitary gland represents the hub of our endocrine system. Its cells produce specific hormones that direct multiple vital physiological processes such as body growth, fertility, and stress. The gland also contains a population of stem cells whic
Externí odkaz:
https://doaj.org/article/5b53d03f086548d6a89b2b79ccc0d44f
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Recently, we discovered that the cytokine interleukin-6 (IL-6) acts as a pituitary stem cell-activating factor, both when administered in vivo and when added to stem cell organoid cultures in vitro. Moreover, its expression, predominantly localized i
Externí odkaz:
https://doaj.org/article/91dfcc0236014472b604aa28375cfe11
Autor:
Emma Laporte, Florian Hermans, Silke De Vriendt, Annelies Vennekens, Diether Lambrechts, Charlotte Nys, Benoit Cox, Hugo Vankelecom
Publikováno v:
eLife, Vol 11 (2022)
The pituitary represents the endocrine master regulator. In mouse, the gland undergoes active maturation immediately after birth. Here, we in detail portrayed the stem cell compartment of neonatal pituitary. Single-cell RNA-sequencing pictured an act
Externí odkaz:
https://doaj.org/article/0efcee480a6f48e3816e78f63c5b172b
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2021)
The pituitary gland has the primordial ability to dynamically adapt its cell composition to changing hormonal needs of the organism throughout life. During the first weeks after birth, an impressive growth and maturation phase is occurring in the gla
Externí odkaz:
https://doaj.org/article/da2337097b314ef8ace11e1964a252d0
Autor:
Charlotte Nys, Yu-Lun Lee, Heleen Roose, Freya Mertens, Ellen De Pauw, Hiroto Kobayashi, Raf Sciot, Marie Bex, Georges Versyck, Steven De Vleeschouwer, Johannes Van Loon, Emma Laporte, Hugo Vankelecom
Publikováno v:
Endocrine-Related Cancer. 29:427-450
Pituitary tumorigenesis is highly prevalent and causes major endocrine disorders. Hardly anything is known on the behavior of the local stem cells in this pathology. Here, we explored the stem cells’ biology in mouse and human pituitary tumors usin
Publikováno v:
Journal of visualized experiments : JoVE. (180)
The pituitary is the master endocrine gland regulating key physiological processes, including body growth, metabolism, sexual maturation, reproduction, and stress response. More than a decade ago, stem cells were identified in the pituitary gland. Ho
Publikováno v:
Journal of Visualized Experiments.
Autor:
Hugo Vankelecom, Emma Laporte
Publikováno v:
Nature Reviews Endocrinology. 18:395-396
ispartof: NATURE REVIEWS ENDOCRINOLOGY vol:18 issue:7 pages:395-396 ispartof: location:England status: published
Autor:
Charlotte Nys, Patrick Matthys, Adrian Janiszewski, Emma Laporte, Diether Lambrechts, Elodie Modave, Marie-Isabelle Garcia, Hiroto Kobayashi, Benoit Cox, Joel Chappell, Vincent Pasque, Florient Hermans, Hugo Vankelecom, Bert Malengier-Devlies, Annelies Vennekens
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Stem cells in the adult pituitary are quiescent yet show acute activation upon tissue injury. The molecular mechanisms underlying this reaction are completely unknown. We applied single-cell transcriptomics to start unraveling the acute pituitary ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49dd5b500ecf3aa1376b85335bd344f
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/323041
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/323041