Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Emma Lai"'
Publikováno v:
npj Primary Care Respiratory Medicine, Vol 31, Iss 1, Pp 1-6 (2021)
Abstract Sputum colour may mark bacterial involvement in acute exacerbations of chronic obstructive pulmonary disease (COPD). However, whether colour vision deficiency (CVD) in COPD patients could impact the use of sputum colour charts as part of a g
Externí odkaz:
https://doaj.org/article/cf2ba5493672448aa773211308d4111e
Autor:
Michael J. R. Desborough, Emma Laing, Daphne Kounali, Ana Mora, Renate Hodge, Siobhan Martin, Helen Thomas, Cara Hudson, Joseph Parsons, Akshay Shah, Paula Hutton, Tim Parke, Matthew P. Wise, Matthew Morgan, Stuart McKechnie, Simon J. Stanworth
Publikováno v:
eJHaem, Vol 5, Iss 4, Pp 772-777 (2024)
Abstract Thrombocytopenic patients have an increased risk of bleeding when undergoing invasive procedures. In a multicentre, phase II, blinded, randomised, controlled feasibility trial, critically ill patients with platelet count 100 × 109/L or less
Externí odkaz:
https://doaj.org/article/795e0b5869aa48bb8e902ebb8d73db90
Publikováno v:
npj Primary Care Respiratory Medicine, Vol 31, Iss 1, Pp 1-6 (2021)
NPJ Primary Care Respiratory Medicine
NPJ Primary Care Respiratory Medicine
Sputum colour may mark bacterial involvement in acute exacerbations of chronic obstructive pulmonary disease (COPD). However, whether colour vision deficiency (CVD) in COPD patients could impact the use of sputum colour charts as part of a guide to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f76631107ad739a7e8f90996f9ef146
https://doi.org/10.1038/s41533-021-00225-z
https://doi.org/10.1038/s41533-021-00225-z
Autor:
James Richards, Dominic Summers, Anna Sidders, Elisa Allen, Mohammed Ayaz Hossain, Subhankar Paul, Matthew Slater, Matthew Bartlett, Regin Lagaac, Emma Laing, Valerie Hopkins, Chloe Fitzpatrick-Creamer, Cara Hudson, Joseph Parsons, Samuel Turner, Andrew Tambyraja, Subash Somalanka, James Hunter, Sam Dutta, Neil Hoye, Sarah Lawman, Tracey Salter, Mohammed Farid Aslam, Atul Bagul, Rajesh Sivaprakasam, George E Smith, Helen L Thomas, Zia Moinuddin, Simon R Knight, Nicholas Barnett, Reza Motallebzadeh, Gavin J Pettigrew
Publikováno v:
Health Technology Assessment, Vol 28, Iss 24 (2024)
Background Arteriovenous fistulas are considered the best option for haemodialysis provision, but as many as 30% fail to mature or suffer early failure. Objective To assess the feasibility of performing a randomised controlled trial that examines whe
Externí odkaz:
https://doaj.org/article/15942e4e9159422eb636ade80f262806
Publikováno v:
Frontiers in Audiology and Otology, Vol 2 (2024)
IntroductionThe use of telehealth for cochlear implant (CI) and hearing aid service provision has the potential to provide efficient, effective, and equitable services to users. However, clinicians require evidence that remote technologies provide ca
Externí odkaz:
https://doaj.org/article/1aa718dbfb7147cd8e404ae007cce1f1
Autor:
Jason E. Smith, Ed B. G. Barnard, Charlie Brown-O’Sullivan, Rebecca Cardigan, Jane Davies, Annie Hawton, Emma Laing, Joanne Lucas, Richard Lyon, Gavin D. Perkins, Laura Smith, Simon J. Stanworth, Anne Weaver, Tom Woolley, Laura Green
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-14 (2023)
Abstract Background Early blood transfusion improves survival in patients with life-threatening bleeding, but the optimal transfusion strategy in the pre-hospital setting has yet to be established. Although there is some evidence of benefit with the
Externí odkaz:
https://doaj.org/article/87e95c9c1ba846af8e30e3d7a2c92c98
Autor:
Layla Hosseini-Gerami, Ixavier Alonzo Higgins, David A. Collier, Emma Laing, David Evans, Howard Broughton, Andreas Bender
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-28 (2023)
Abstract Background Elucidating compound mechanism of action (MoA) is beneficial to drug discovery, but in practice often represents a significant challenge. Causal Reasoning approaches aim to address this situation by inferring dysregulated signalli
Externí odkaz:
https://doaj.org/article/0d25a68bc88b4eda8c60ccb5c1863ac9
Autor:
Layla Hosseini-Gerami, Elena Ficulle, Neil Humphryes-Kirilov, David C. Airey, James Scherschel, Sarubini Kananathan, Brian J. Eastwood, Suchira Bose, David A. Collier, Emma Laing, David Evans, Howard Broughton, Andreas Bender
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Background A key histopathological hallmark of Alzheimer’s disease (AD) is the presence of neurofibrillary tangles of aggregated microtubule-associated protein tau in neurons. Anle138b is a small molecule which has previously shown efficac
Externí odkaz:
https://doaj.org/article/5f63ecb9bfa34970acca9a7c9e02d8ec
Autor:
Elena Ficulle, Sarubini Kananathan, David Airey, Severine I. Gharbi, Neil Humphryes-Kirilov, James Scherschel, Charlotte Dunbar, Brian J. Eastwood, Emma Laing, David A. Collier, Suchira Bose
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Cellular models recapitulating features of tauopathies are useful tools to investigate the causes and consequences of tau aggregation and the identification of novel treatments. We seeded rat primary cortical neurons with tau isolated from A
Externí odkaz:
https://doaj.org/article/39c8fee083e94653b2562d52cd41338e
Autor:
Cathrine Axfors, Perrine Janiaud, Andreas M. Schmitt, Janneke van’t Hooft, Emily R. Smith, Noah A. Haber, Akin Abayomi, Manal Abduljalil, Abdulkarim Abdulrahman, Yeny Acosta-Ampudia, Manuela Aguilar-Guisado, Farah Al-Beidh, Marissa M. Alejandria, Rachelle N. Alfonso, Mohammad Ali, Manaf AlQahtani, Alaa AlZamrooni, Juan-Manuel Anaya, Mark Angelo C. Ang, Ismael F. Aomar, Luis E. Argumanis, Alexander Averyanov, Vladimir P. Baklaushev, Olga Balionis, Thomas Benfield, Scott Berry, Nadia Birocco, Lynn B. Bonifacio, Asha C. Bowen, Abbie Bown, Carlos Cabello-Gutierrez, Bernardo Camacho, Adrian Camacho-Ortiz, Sally Campbell-Lee, Damon H. Cao, Ana Cardesa, Jose M. Carnate, German Jr. J. Castillo, Rossana Cavallo, Fazle R. Chowdhury, Forhad U. H. Chowdhury, Giovannino Ciccone, Antonella Cingolani, Fresthel Monica M. Climacosa, Veerle Compernolle, Carlo Francisco N. Cortez, Abel Costa Neto, Sergio D’Antico, James Daly, Franca Danielle, Joshua S. Davis, Francesco Giuseppe De Rosa, Justin T. Denholm, Claudia M. Denkinger, Daniel Desmecht, Juan C. Díaz-Coronado, Juan A. Díaz Ponce-Medrano, Anne-Françoise Donneau, Teresita E. Dumagay, Susanna Dunachie, Cecile C. Dungog, Olufemi Erinoso, Ivy Mae S. Escasa, Lise J. Estcourt, Amy Evans, Agnes L. M. Evasan, Christian J. Fareli, Veronica Fernandez-Sanchez, Claudia Galassi, Juan E. Gallo, Patricia J. Garcia, Patricia L. Garcia, Jesus A. Garcia, Mutien Garigliany, Elvira Garza-Gonzalez, Deonne Thaddeus V. Gauiran, Paula A. Gaviria García, Jose-Antonio Giron-Gonzalez, David Gómez-Almaguer, Anthony C. Gordon, André Gothot, Jeser Santiago Grass Guaqueta, Cameron Green, David Grimaldi, Naomi E. Hammond, Heli Harvala, Francisco M. Heralde, Jesica Herrick, Alisa M. Higgins, Thomas E. Hills, Jennifer Hines, Karin Holm, Ashraful Hoque, Eric Hoste, Jose M. Ignacio, Alexander V. Ivanov, Maike Janssen, Jeffrey H. Jennings, Vivekanand Jha, Ruby Anne N. King, Jens Kjeldsen-Kragh, Paul Klenerman, Aditya Kotecha, Fiorella Krapp, Luciana Labanca, Emma Laing, Mona Landin-Olsson, Pierre-François Laterre, Lyn-Li Lim, Jodor Lim, Oskar Ljungquist, Jorge M. Llaca-Díaz, Concepción López-Robles, Salvador López-Cárdenas, Ileana Lopez-Plaza, Josephine Anne C. Lucero, Maria Lundgren, Juan Macías, Sandy C. Maganito, Anna Flor G. Malundo, Rubén D. Manrique, Paola M. Manzini, Miguel Marcos, Ignacio Marquez, Francisco Javier Martínez-Marcos, Ana M. Mata, Colin J. McArthur, Zoe K. McQuilten, Bryan J. McVerry, David K. Menon, Geert Meyfroidt, Ma. Angelina L. Mirasol, Benoît Misset, James S. Molton, Alric V. Mondragon, Diana M. Monsalve, Parastoo Moradi Choghakabodi, Susan C. Morpeth, Paul R. Mouncey, Michel Moutschen, Carsten Müller-Tidow, Erin Murphy, Tome Najdovski, Alistair D. Nichol, Henrik Nielsen, Richard M. Novak, Matthew V. N. O’Sullivan, Julian Olalla, Akin Osibogun, Bodunrin Osikomaiya, Salvador Oyonarte, Juan M. Pardo-Oviedo, Mahesh C. Patel, David L. Paterson, Carlos A. Peña-Perez, Angel A. Perez-Calatayud, Eduardo Pérez-Alba, Anastasia Perkina, Naomi Perry, Mandana Pouladzadeh, Inmaculada Poyato, David J. Price, Anne Kristine H. Quero, Md. M. Rahman, Md. S. Rahman, Mayur Ramesh, Carolina Ramírez-Santana, Magnus Rasmussen, Megan A. Rees, Eduardo Rego, Jason A. Roberts, David J. Roberts, Yhojan Rodríguez, Jesús Rodríguez-Baño, Benjamin A. Rogers, Manuel Rojas, Alberto Romero, Kathryn M. Rowan, Fabio Saccona, Mehdi Safdarian, Maria Clariza M. Santos, Joe Sasadeusz, Gitana Scozzari, Manu Shankar-Hari, Gorav Sharma, Thomas Snelling, Alonso Soto, Pedrito Y. Tagayuna, Amy Tang, Geneva Tatem, Luciana Teofili, Steven Y. C. Tong, Alexis F. Turgeon, Januario D. Veloso, Balasubramanian Venkatesh, Yanet Ventura-Enriquez, Steve A. Webb, Lothar Wiese, Christian Wikén, Erica M. Wood, Gaukhar M. Yusubalieva, Kai Zacharowski, Ryan Zarychanski, Nina Khanna, David Moher, Steven N. Goodman, John P. A. Ioannidis, Lars G. Hemkens
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-23 (2021)
Abstract Background Convalescent plasma has been widely used to treat COVID-19 and is under investigation in numerous randomized clinical trials, but results are publicly available only for a small number of trials. The objective of this study was to
Externí odkaz:
https://doaj.org/article/6bad8c19b16b4268afed0c169d14cf14