Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Emma L. Wilson"'
Autor:
Emma L. Wilson, Yizhou Yu, Nuno S. Leal, James A. Woodward, Nikolaos Patikas, Jordan L. Morris, Sarah F. Field, William Plumbly, Vincent Paupe, Suvagata R. Chowdhury, Robin Antrobus, Georgina E. Lindop, Yusuf M. Adia, Samantha H. Y. Loh, Julien Prudent, L. Miguel Martins, Emmanouil Metzakopian
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-16 (2024)
Abstract Organelles form membrane contact sites between each other, allowing for the transfer of molecules and signals. Mitochondria-endoplasmic reticulum (ER) contact sites (MERCS) are cellular subdomains characterized by close apposition of mitocho
Externí odkaz:
https://doaj.org/article/2914aeb333b24972878c1604812247ee
Autor:
Benjamin J. Tuck, Lauren V.C. Miller, Taxiarchis Katsinelos, Annabel E. Smith, Emma L. Wilson, Sophie Keeling, Shi Cheng, Marina J. Vaysburd, Claire Knox, Lucy Tredgett, Emmanouil Metzakopian, Leo C. James, William A. McEwan
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110776- (2022)
Summary: Assemblies of tau can transit between neurons, seeding aggregation in a prion-like manner. To accomplish this, tau must cross cell-limiting membranes, a process that is poorly understood. Here, we establish assays for the study of tau entry
Externí odkaz:
https://doaj.org/article/538c66f388cf44be883cb205f710e4fd
Autor:
Charlotte H. Hulme, Emma L. Wilson, Heidi R. Fuller, Sally Roberts, James B. Richardson, Pete Gallacher, Mandy J. Peffers, Sally L. Shirran, Catherine H. Botting, Karina T. Wright
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-17 (2018)
Abstract Background Autologous chondrocyte implantation (ACI) has a failure rate of approximately 20%, but it is yet to be fully understood why. Biomarkers are needed that can pre-operatively predict in which patients it is likely to fail, so that al
Externí odkaz:
https://doaj.org/article/42be40ada3ed4d8b9a54fce0c43c0ef2
Autor:
Charlotte H. Hulme, Emma L. Wilson, Mandy J. Peffers, Sally Roberts, Deborah M. Simpson, James B. Richardson, Pete Gallacher, Karina T. Wright
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-15 (2017)
Abstract Background Autologous chondrocyte implantation (ACI) can be used in the treatment of focal cartilage injuries to prevent the onset of osteoarthritis (OA). However, we are yet to understand fully why some individuals do not respond well to th
Externí odkaz:
https://doaj.org/article/9db8319368e94ff4a3901dc41e4e463f
Autor:
Paul Jermin, Gabriel Mateus Bernardo Harrington, Emma L. Wilson, Karina T. Wright, Mandy J. Peffers, Charlotte H Hulme, Sally Roberts, Jade Perry, Pete Gallacher
Publikováno v:
AMERICAN JOURNAL OF SPORTS MEDICINE
Background: Biomarkers are needed to predict clinical outcomes for microfracture and osteotomy surgeries to ensure patients can be better stratified to receive the most appropriate treatment. Purpose: To identify novel biomarker candidates and to inv
Balanced mitochondrial fission and fusion play an important role in shaping and distributing mitochondria, as well as contributing to mitochondrial homeostasis and adaptation to stress. In particular, mitochondrial fission is required to facilitate d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ee21a00d240335db32cf5b2dfa2f78
https://doi.org/10.1101/2020.05.13.093823
https://doi.org/10.1101/2020.05.13.093823
Publikováno v:
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 726 (2020)
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 726 (2020)
Umbilical cord mesenchymal stromal cells (UCMSCs) have shown an ability to modulate the immune system through the secretion of paracrine mediators, such as extracellular vesicles (EVs). However, the culture conditions that UCMSCs are grown in can alt
Autor:
Pete Gallacher, Catherine H. Botting, Sally Roberts, Mandy J. Peffers, James B. Richardson, Heidi R. Fuller, Sally L. Shirran, Charlotte H Hulme, Karina T. Wright, Emma L. Wilson
Publikováno v:
ARTHRITIS RESEARCH & THERAPY
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-17 (2018)
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-17 (2018)
Arthritis Research & Therapy
Background Autologous chondrocyte implantation (ACI) has a failure rate of approximately 20%, but it is yet to be fully understood why. Biomarkers are needed that can pre-operatively predict in which patients it is likely to fail, so that alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f3325e5323a15219c8304eca433009
https://hdl.handle.net/10023/13288
https://hdl.handle.net/10023/13288
Phenytoin is an antiepileptic drug used in the management of partial and tonic-clonic seizures. In previous studies we have shown that valproate, another antiepileptic drug, reduced the amount of two key bone proteins, pro-collagen I and osteonectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880a6d416b6cb8e86e347893a174d4b4
Autor:
Catherine H. Botting, Karina T. Wright, James B. Richardson, Charlotte H Hulme, Pete Gallacher, Sally L. Shirran, Sally Roberts, Emma L. Wilson, Mandy J. Peffers, Heidi R. Fuller
Publikováno v:
OSTEOARTHRITIS AND CARTILAGE
Background: Autologous chondrocyte implantation (ACI) has a failure rate of approximately 20%, but it is yet to be\ud fully understood why. Biomarkers are needed that can pre-operatively predict in which patients it is likely to fail, so\ud that alte