Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Emma L. Wilkinson"'
Autor:
Hanaa A. Galeb, Emma L. Wilkinson, Alison F. Stowell, Hungyen Lin, Samuel T. Murphy, Pierre L. Martin‐Hirsch, Richard L. Mort, Adam M. Taylor, John G. Hardy
Publikováno v:
Global Challenges, Vol 5, Iss 2, Pp n/a-n/a (2021)
Abstract Melanins are a class of biopolymers that are widespread in nature and have diverse origins, chemical compositions, and functions. Their chemical, electrical, optical, and paramagnetic properties offer opportunities for applications in materi
Externí odkaz:
https://doaj.org/article/9f59c27e3af943048a8537d184eeeca7
Publikováno v:
Biology Open, Vol 5, Iss 10, Pp 1362-1370 (2016)
Cardiotoxicity induced by anti-cancer therapeutics is a severe, and potentially fatal, adverse reaction of the heart in response to certain drugs. Current in vitro approaches to assess cardiotoxicity have focused on analysing cardiomyocytes. More rec
Externí odkaz:
https://doaj.org/article/cfc651f0eefb4c6b8dcf72d91b27fa3d
Autor:
Emma L. Wilkinson, Louise C. Brennan, Olivia J. Harrison, Zoe Crane‐Smith, Philippe Gautier, Margaret A. Keighren, Peter Budd, Karthic Swaminathan, Laura M. Machesky, Sarah L. Allinson, Ian J. Jackson, Richard L. Mort
Publikováno v:
Pigment Cell & Melanoma Research. 36:71-77
Genetic approaches that allow lineage tracing are essential to our future understanding of melanocytes and melanoma. To date, the approaches used to label melanocytes in mice have relied on random integration of transgenes driven by the promoters of
Publikováno v:
Experimental Dermatology. 31:1543-1553
Raman spectroscopy is an emerging dermatological technique with the potential to discriminate biochemically between cell types in a label-free and non-invasive manner. Here, we use live single-cell Raman spectroscopy and principal component analysis
Raman spectroscopy is an emerging dermatological technique with the potential to discriminate biochemically between cell types in a label free and non-invasive manner. Here we use live single cell Raman spectroscopy and principal component analysis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::227178f83c733b81714ffd52523e52bf
https://doi.org/10.1101/2021.11.12.468396
https://doi.org/10.1101/2021.11.12.468396
Autor:
Rowena Sison-Young, Min Wei Wong, Chris S. Pridgeon, Michael J. Cross, Christopher E. Goldring, John Greenman, James E. Sidaway, Vitalina Gryshkova, Joseph Leedale, Paul Walker, Tahera Ansari, Emma L. Wilkinson, Laurence Launay, Susan Gibbs, B. Kevin Park, Tobias Heckel, Stefan Przyborski, R. N. Bearon, Constanze Schlott, Minne B. Heringa, Delilah F. G. Hendriks
Publikováno v:
Pridgeon, C S, Schlott, C, Wong, M W, Heringa, M B, Heckel, T, Leedale, J, Launay, L, Gryshkova, V, Przyborski, S, Bearon, R N, Wilkinson, E L, Ansari, T, Greenman, J, Hendriks, D F G, Gibbs, S, Sidaway, J, Sison-Young, R L, Walker, P, Cross, M J, Park, B K & Goldring, C E P 2018, ' Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms ', Archives of Toxicology, vol. 92, no. 2, pp. 557-569 . https://doi.org/10.1007/s00204-018-2152-9
Archives of Toxicology
Archives of Toxicology
The development of improved, innovative models for the detection of toxicity of drugs, chemicals, or chemicals in cosmetics is crucial to efficiently bring new products safely to market in a cost-effective and timely manner. In addition, improvement
Autor:
Ahmad F. Alghanem, Michael J. Cross, Victoria L. Heath, Mohammad A. Aljasir, Emma L. Wilkinson, Beverley A. Rothermel, Katherine Holmes, Victoria A. Simms, Maxine S. Emmett
Publikováno v:
Angiogenesis
Regulator of calcineurin 1 (RCAN1) is an endogenous inhibitor of the calcineurin pathway in cells. It is expressed as two isoforms in vertebrates: RCAN1.1 is constitutively expressed in most tissues, whereas transcription of RCAN1.4 is induced by sev
Autor:
Samuel T. Murphy, Pierre L. Martin‐Hirsch, John G. Hardy, Emma L. Wilkinson, Adam Michael Taylor, Alison Stowell, Hungyen Lin, Richard L. Mort, Hanaa A. Galeb
Publikováno v:
Global Challenges, Vol 5, Iss 2, Pp n/a-n/a (2021)
Global Challenges
Global Challenges
Melanins are a class of biopolymers that are widespread in nature and have diverse origins, chemical compositions, and functions. Their chemical, electrical, optical, and paramagnetic properties offer opportunities for applications in materials scien
Autor:
Steffen Rädisch, Hassan Malik, David Dickens, Munir Pirmohamed, Rowena Sison-Young, George N. Chiduza, Emma L. Wilkinson, Elke Schaeffeler, Anne T. Nies, Christopher E. Goldring, Athina Giannoudis, Matthias Schwab, Michael J. Cross
Publikováno v:
Molecular Pharmaceutics
The weak base antipsychotic clozapine is the most effective medication for treating refractory schizophrenia. The brain-to-plasma concentration of unbound clozapine is greater than unity, indicating transporter-mediated uptake, which has been insuffi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c737906d9da54cf63c9a9eb9104a52e3