Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Emma L. Scott"'
Autor:
Asma Ahmad Shariff, Maryam Ahmed, Sandra Alemany, Alfredo Ballester, Juan Carlos González, Simeon Gill, Monika Januszkiewicz, Suhana Japar, Vishaka Karnad, Chan Chee Kooi, Cordelia Mason, Beatriz Nácher, Eduardo Parrilla, Jie Pei, Zhang Qian, Alfredo Remon, Wan Syazehan Ruznan, Amna Saad, Nurashikin Saaludin, Emma L. Scott, Norazmi Shahlal, Shaliza Mohd Shariff, Vrinda Udiaver, Juan Vicente Durá, Anastasia Vouyouka, Gordon Wong, Norsaadah Zakaria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c993b459408ddaca504ea6bb439fdc9d
https://doi.org/10.1016/b978-0-12-823969-8.00016-2
https://doi.org/10.1016/b978-0-12-823969-8.00016-2
Autor:
Emma L. Scott, Thomas C. J. Hill, Sonia Lasher-Trapp, Christina S. McCluskey, Fritz Waitz, Martin Schnaiter, Emma Järvinen, Paul J. DeMott
Publikováno v:
Journal of Geophysical Research: Atmospheres. 126
Autor:
Molly E. V. Swanson, Miran Mrkela, Helen C. Murray, Maize C. Cao, Clinton Turner, Maurice A. Curtis, Richard L. M. Faull, Adam K. Walker, Emma L. Scotter
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-22 (2023)
Abstract Microglia, the innate immune cells of the brain, are activated by damage or disease. In mouse models of amyotrophic lateral sclerosis (ALS), microglia shift from neurotrophic to neurotoxic states with disease progression. It remains unclear
Externí odkaz:
https://doaj.org/article/ffaa51da88b7483d88b75ccc62336f16
Autor:
Maize C. Cao, Brigid Ryan, Jane Wu, Maurice A. Curtis, Richard L.M. Faull, Mike Dragunow, Emma L. Scotter
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106245- (2023)
TDP-43 dysfunction is a molecular hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). A major hypothesis of TDP-43 dysfunction in disease is the loss of normal nuclear function, resulting in impaired RNA regulation and
Externí odkaz:
https://doaj.org/article/8e5f99125ab542caac7f334399448b57
Autor:
Maize C. Cao, Erin E. Cawston, Grace Chen, Collin Brooks, Jeroen Douwes, Dave McLean, E. Scott Graham, Mike Dragunow, Emma L. Scotter
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Amyotrophic lateral sclerosis (ALS) is an incurable and rapidly progressive neurological disorder. Biomarkers are critical to understanding disease causation, monitoring disease progression and assessing the efficacy of treatments. However,
Externí odkaz:
https://doaj.org/article/43fcd70d92914590b6a31c00e5751e33
Autor:
Maize C. Cao, Emma L. Scotter
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/9d5f5e125d504d2889719679238a4b39
Autor:
Molly E. V. Swanson, Emma L. Scotter, Leon C. D. Smyth, Helen C. Murray, Brigid Ryan, Clinton Turner, Richard L. M. Faull, Mike Dragunow, Maurice A. Curtis
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-16 (2020)
Abstract In Alzheimer’s disease (AD), microglia are affected by disease processes, but may also drive pathogenesis. AD pathology-associated microglial populations have been identified with single-cell RNA-Seq, but have not been validated in human b
Externí odkaz:
https://doaj.org/article/fd4bdb9a974b40289fbe32b437cd3db9
Autor:
Pritika Narayan, Suzanne Reid, Emma L. Scotter, Ailsa L. McGregor, Nasim F. Mehrabi, Malvindar K. Singh-Bains, Michelle Glass, Richard L.M. Faull, Russell G. Snell, Mike Dragunow
Publikováno v:
Neurobiology of Disease, Vol 146, Iss , Pp 105092- (2020)
Huntington's disease (HD) is a neurodegenerative disorder caused by a CAG trinucleotide repeat expansion in exon 1 of the huntingtin gene. Emerging evidence shows that additional epigenetic factors can modify disease phenotypes. Harnessing the abilit
Externí odkaz:
https://doaj.org/article/46c0279f44bc402698babefffb127715
Autor:
Sreemol Gokuladhas, William Schierding, David Cameron-Smith, Melissa Wake, Emma L. Scotter, Justin O’Sullivan
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Muscle weakness is a common consequence of both aging (sarcopenia) and neuromuscular disorders (NMD). Whilst genome-wide association (GWA) studies have identified genetic variants associated with grip strength (GS; measure of muscle strength/weakness
Externí odkaz:
https://doaj.org/article/648f8f8a8af14bdb836b9cb5ee36da22
Autor:
Justin Rustenhoven, Amy M. Smith, Leon C. Smyth, Deidre Jansson, Emma L. Scotter, Molly E. V. Swanson, Miranda Aalderink, Natacha Coppieters, Pritika Narayan, Renee Handley, Chris Overall, Thomas I. H. Park, Patrick Schweder, Peter Heppner, Maurice A. Curtis, Richard L. M. Faull, Mike Dragunow
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-16 (2018)
Abstract Background Microglia play critical roles in the brain during homeostasis and pathological conditions. Understanding the molecular events underpinning microglial functions and activation states will further enable us to target these cells for
Externí odkaz:
https://doaj.org/article/61d01fe126004e1d9256ea1766c25fa5