Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Emma L. Lewis"'
Autor:
Emma L. Lewis, Erin R. Reichenberger, Lauren Anton, Michael V. Gonzalez, Deanne M. Taylor, Paige M. Porrett, Michal A. Elovitz
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Intrauterine fetal demise (IUFD) – fetal loss after 20 weeks – affects 6 pregnancies per 1,000 live births in the United States, and the majority are of unknown etiology. Maternal systemic regulatory T cell (Treg) deficits have been implicated in
Externí odkaz:
https://doaj.org/article/a34b946728f0472283ee53b920e20a46
Autor:
Emma L. Lewis, Natalia Tulina, Lauren Anton, Amy G. Brown, Paige M. Porrett, Michal A. Elovitz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Intrauterine inflammation impacts prenatal neurodevelopment and is linked to adverse neurobehavioral outcomes ranging from cerebral palsy to autism spectrum disorder. However, the mechanism by which a prenatal exposure to intrauterine inflammation co
Externí odkaz:
https://doaj.org/article/17f35e272a4a4958ada0ff4c4c6a3b0c
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract The cholesterol dependent cytolysins (CDCs) are a family of pore-forming toxins produced by a wide range of bacteria. Some CDCs are important virulence factors for their cognate organisms, but their activity must be tightly regulated to ensu
Externí odkaz:
https://doaj.org/article/aea011bfef974b26a9bb104e9cc10ed8
Autor:
Emma L. Lewis, Rong Xu, Jean-Christophe Beltra, Shin Foong Ngiow, Jordana Cohen, Rahul Telange, Alexander Crane, Deirdre Sawinski, E. John Wherry, Paige M. Porrett
Publikováno v:
Journal of Experimental Medicine. 219
Pregnancy is a common immunization event, but the molecular mechanisms and immunological consequences provoked by pregnancy remain largely unknown. We used mouse models and human transplant registry data to reveal that pregnancy induced exhausted CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cfc773b797072223f291339b39bf31
https://doi.org/10.1084/jem.20201599
https://doi.org/10.1084/jem.20201599
Autor:
Paula M. Oliver, Asif Amin Dar, Emily K Moser, Eddie Park, Lynn A. Spruce, Steven H. Seeholzer, Emma L. Lewis, Joseph M Dybas, Keisuke Sawada, Hossein Fazelinia, Hua Ding
Publikováno v:
PLoS Biology, Vol 19, Iss 2, p e3001041 (2021)
PLoS Biology
PLoS Biology
The capacity for T cells to become activated and clonally expand during pathogen invasion is pivotal for protective immunity. Our understanding of how T cell receptor (TCR) signaling prepares cells for this rapid expansion remains limited. Here we pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13928ffd424e36a9b3728364b68f3b94
https://doaj.org/article/1ccf70c70537433581dda2a256654825
https://doaj.org/article/1ccf70c70537433581dda2a256654825
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Scientific Reports
The cholesterol dependent cytolysins (CDCs) are a family of pore-forming toxins produced by a wide range of bacteria. Some CDCs are important virulence factors for their cognate organisms, but their activity must be tightly regulated to ensure they o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f821784d9acb2210476deead2efd9c
https://doaj.org/article/aea011bfef974b26a9bb104e9cc10ed8
https://doaj.org/article/aea011bfef974b26a9bb104e9cc10ed8
Publikováno v:
The Journal of Immunology. 206:17.11-17.11
Intrauterine fetal demise (IUFD) – fetal loss after 20 weeks – affects 6 pregnancies per 1,000 live births in the United States, and the majority of IUFDs are of unknown etiology. We investigated immunological mechanisms of IUFD using the CBA mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a50b211fe983214de6558da31038e84
https://doi.org/10.4049/jimmunol.206.supp.17.11
https://doi.org/10.4049/jimmunol.206.supp.17.11
Autor:
Shari E. Gelber, Victor Nizet, Adam J. Ratner, Tara M. Randis, Emma L. Lewis, Leor H. Akabas, Thomas A. Hooven, Rosanna G. Abellar, Lindsay B. Walker, Leah M. Byland
Publikováno v:
Journal of Infectious Diseases. 210:265-273
Background. Maternal vaginal colonization with Streptococcus agalactiae (Group B Streptococcus [GBS]) is a precursor to chorioamnionitis, fetal infection, and neonatal sepsis, but the understanding of specific factors in the pathogenesis of ascending
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f7b82cd9aed73cec15b6aeea88d936
https://doi.org/10.1093/infdis/jiu067
https://doi.org/10.1093/infdis/jiu067
Autor:
Fábio E. Amaral, Timothy J. LaRocca, Adam J. Ratner, Ryan Rampersaud, Purnahamsi Desai, Emma L. Lewis, Tara M. Randis, Joanne Zaklama, Ferdinand C. O. Los
Publikováno v:
Infection and Immunity. 81:4544-4550
Gardnerella vaginalis , the bacterial species most frequently isolated from women with bacterial vaginosis (BV), produces a cholesterol-dependent cytolysin (CDC), vaginolysin (VLY). At sublytic concentrations, CDCs may initiate complex signaling casc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1d2eb8d2cdd66b547bac820f079a35
https://doi.org/10.1128/iai.00627-13
https://doi.org/10.1128/iai.00627-13
Autor:
Leah M. Byland, Emma L. Lewis, Jacqueline A. Baker, Adam J. Ratner, Tara M. Randis, Maryam Bonakdar
Publikováno v:
Vaccine. 35(9)
Group B Streptococcus (GBS) is a leading cause of morbidity and mortality in infants, and colonization of the maternal genital tract is the primary risk factor for newborn infection. Despite the importance of mucosal colonization in GBS pathogenesis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae9ac4675d8d0ce8d48c732c23f9904
https://pubmed.ncbi.nlm.nih.gov/28162823
https://pubmed.ncbi.nlm.nih.gov/28162823