Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Emma L. Culver"'
Autor:
Rodrigo V. Motta, Emma L. Culver
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Immunoglobulins are an essential part of the humoral immune response. IgG4 antibodies are the least prevalent subclass and have unique structural and functional properties. In this review, we discuss IgG4 class switch and B cell production. We review
Externí odkaz:
https://doaj.org/article/4aa65a591f8e49c6bdc59e069aedcd4e
Autor:
Cory Perugino, Emma L. Culver, Arezou Khosroshahi, Wen Zhang, Emanuel Della-Torre, Kazuichi Okazaki, Yoshiya Tanaka, Matthias Löhr, Nicolas Schleinitz, Judith Falloon, Dewei She, Daniel Cimbora, John H. Stone
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 6, Pp 1795-1808 (2023)
Abstract Introduction Immunoglobulin G4-related disease (IgG4-RD) is a debilitating multiorgan disease characterized by recurring flares leading to organ dysfunction, decreased quality of life, and mortality. Glucocorticoids, the standard of care for
Externí odkaz:
https://doaj.org/article/8fd489c2c4564ecf821166afa716dc2e
Autor:
Emmanuel A. Selvaraj, Ahmed Ba‐Ssalamah, Sarah Poetter‐Lang, Gerard R. Ridgway, J. Michael Brady, Jane Collier, Emma L. Culver, Adam Bailey, Michael Pavlides
Publikováno v:
Hepatology Communications, Vol 6, Iss 4, Pp 795-808 (2022)
Magnetic resonance imaging with magnetic resonance cholangiopancreatography (MRI‐MRCP) in primary sclerosing cholangitis (PSC) is currently based on qualitative assessment and has high interobserver variability. We investigated the utility and perf
Externí odkaz:
https://doaj.org/article/52587d5f5178454791787a74c9d28325
Autor:
Brian E. Fratto, Emma L. Culver, Gabriel Davis, Robert Deans, John B. Goods, Sean Hwang, Nicole K. Keller, John A. Lawrence, Alexander R. Petty, Timothy M. Swager, Joseph J. Walish, Zhengguo Zhu, Jason R. Cox
Publikováno v:
PLoS ONE, Vol 18, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/c73c677e1f4748248266695828857683
Autor:
Michael A. Heneghan, Elizabeth Shumbayawonda, Andrea Dennis, Refah Z. Ahmed, Mussarat N. Rahim, Michael Ney, Loren Smith, Matt Kelly, Rajarshi Banerjee, Emma L. Culver
Publikováno v:
EClinicalMedicine, Vol 46, Iss , Pp 101325- (2022)
Summary: Background: In autoimmune hepatitis (AIH), clinical practice and treatment guidelines frequently diverge as a reflection of disease heterogeneity and challenges in achieving standardised care. We sought to explore the utility of multiparamet
Externí odkaz:
https://doaj.org/article/ef97d13ed24c4a5abdc90998046503d5
Autor:
Rhys D.R. Evans, Tamsin Cargill, George Goodchild, Ben Oliveira, Manuel Rodriguez-Justo, Ruth Pepper, John Connolly, Alan Salama, George Webster, Eleanor Barnes, Emma L. Culver
Publikováno v:
Kidney International Reports, Vol 4, Iss 1, Pp 48-58 (2019)
Introduction: IgG4-related disease (IgG4-RD) is a relapsing multisystem fibro-inflammatory disease, which may involve the kidney (IgG4-related kidney disease [IgG4-RKD]) and retroperitoneum (IgG4-related retroperitoneal fibrosis [IgG4-RPF]). The aim
Externí odkaz:
https://doaj.org/article/3829c28667ef45df814b701a8372a837
Autor:
Tamsin Cargill, Emma L. Culver
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B cells form a branch of the adaptive immune system, essential for the body’s immune defense against pathogens. B cell dysfunction has been implicated in the pathogenesis of immune mediated liver diseases including autoimmune hepatitis, IgG4-relate
Externí odkaz:
https://doaj.org/article/3c6d414bc6a44568a29bb9626f528076
Autor:
Nadir Abbas, Emma L. Culver, Douglas Thorburn, Neil Halliday, Hannah Crothers, Jessica K. Dyson, April Phaw, Richard Aspinall, Salim I. Khakoo, Yiannis Kallis, Belinda Smith, Imran Patanwala, Anne McCune, Chenchu R. Chimakurthi, Vinod Hegade, Michael Orrell, Rebecca Jones, George Mells, Colette Thain, Robert-Mitchell Thain, David Jones, Gideon Hirschfield, Palak J. Trivedi
Publikováno v:
Clinical Gastroenterology and Hepatology. 21:1561-1570.e13
Thirty-to-forty percent of patients with primary biliary cholangitis inadequately respond to ursodeoxycholic acid. Our aim was to assemble national, real-world data on the effectiveness of obeticholic acid (OCA) as a second-line treatment, alongside
Autor:
Olimpia Orozco-Gálvez, Andreu Fernández-Codina, Marco Lanzillotta, Mikael Ebbo, Nicolas Schleinitz, Emma L. Culver, Vinciane Rebours, David P. D'Cruz, Emanuel Della-Torre, Fernando Martínez-Valle
Publikováno v:
Autoimmunity Reviews. 22:103273