Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Emma K, Gowing"'
Autor:
Nane Griem-Krey, Stine J. Gauger, Emma K. Gowing, Louise Thiesen, Bente Frølund, Andrew N. Clarkson, Petrine Wellendorph
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113895- (2022)
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKIIα) is a potential target for acute neuroprotection due to its key role in physiological and pathological glutamate signaling. The hub domain organizes the CaMKII holoenzyme into large oligomer
Externí odkaz:
https://doaj.org/article/6b670604d4114ca48d483c8678e6b24c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11252 (2023)
In attention deficit hyperactivity disorder (ADHD), hyperactivity and impulsivity occur in response to delayed reward. Herein we report a novel animal model in which male Sprague-Dawley rats exposed to repeated hypoxic brain injury during the equival
Externí odkaz:
https://doaj.org/article/04a2db44b3da428cbd407b3d384704a7
Autor:
Gary P. Morris, Emma K. Gowing, Jo‐Maree Courtney, Hannah E. Coombe, Natalie E. King, Sarah S. J. Rewell, David W. Howells, Andrew N. Clarkson, Brad A. Sutherland
Publikováno v:
Journal of Neuroscience Research. 101:278-292
Stroke therapy has largely focused on preventing damage and encouraging repair outside the ischemic core, as the core is considered irreparable. Recently, several studies have suggested endogenous responses within the core are important for limiting
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11252
In attention deficit hyperactivity disorder (ADHD), hyperactivity and impulsivity occur in response to delayed reward. Herein we report a novel animal model in which male Sprague-Dawley rats exposed to repeated hypoxic brain injury during the equival
Autor:
Silke Neumann, Lily Boothman-Burrell, Emma K. Gowing, Thomas A. Jacobsen, Philip K. Ahring, Sarah L. Young, Karin Sandager-Nielsen, Andrew N. Clarkson
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Inflammatory processes are known to contribute to tissue damage in the central nervous system (CNS) across a broad range of neurological conditions, including stroke. Gamma amino butyric acid (GABA), the main inhibitory neurotransmitter in the CNS, h
Externí odkaz:
https://doaj.org/article/16eebc1f4f9344f5b5c5ecb61734f3f8
Publikováno v:
Neural Plasticity, Vol 2019 (2019)
Stroke remains a leading cause of disability worldwide. Recently, we have established an animal model of stroke that results in delayed impairment in spatial memory, allowing us to better investigate cognitive deficits. Young and aged brains show dif
Externí odkaz:
https://doaj.org/article/dac2e9ee5327498790b343f51b6a645b
Autor:
Julien Chuquet, Andrew N. Clarkson, Ann-Britt Marcher, Katarzyna Gach-Janczak, Mahmoud Hazime, David Vaudry, Julie Maucotel, Katia Lehongre, Benjamin Lefranc, Pascale P. Quilichini, Raghavendra Y. Nagaraja, Emma K. Gowing, Susanne Mandrup, Rhita Lamtahri, Jérôme Leprince, Michael Alasoadura
Publikováno v:
Lamtahri, R, Hazime, M, Gowing, E K, Nagaraja, R Y, Maucotel, J, Alasoadura, M, Quilichini, P P, Lehongre, K, Lefranc, B, Gach-Janczak, K, Marcher, A B, Mandrup, S, Vaudry, D, Clarkson, A N, Leprince, J & Chuquet, J 2021, ' The gliopeptide ODN, a ligand for the benzodiazepine site of GABA A receptors, boosts functional recovery after stroke ', Journal of Neuroscience, vol. 41, no. 33, pp. 7148-7159 . https://doi.org/10.1523/JNEUROSCI.2255-20.2021
Journal of Neuroscience
Journal of Neuroscience, 2021, 41 (33), pp.7148-7159. ⟨10.1523/JNEUROSCI.2255-20.2021⟩
Journal of Neuroscience
Journal of Neuroscience, 2021, 41 (33), pp.7148-7159. ⟨10.1523/JNEUROSCI.2255-20.2021⟩
Following stroke, the survival of neurons and their ability to re-establish connections is critical to functional recovery. This is strongly influenced by the balance between neuronal excitation and inhibition. In the acute phase of experimental stro
Autor:
Amanda L Trout, Gregory J. Bix, Bret N. Smith, Stephen Grupke, Antonio Berretta, Andrew N. Clarkson, Ifechukwude Joachim Biose, Carie R. Boychuk, Aileen Marcelo, Jill Roberts, Danielle N. Edwards, Ibolya Rutkai, Michael P. Kahle, Amanda A. Gorman, Masafumi Ihara, Hatsue Ishibashi-Ueda, Emma K. Gowing, Jeffery A. Boychuk, Leon de Hoog
Publikováno v:
Translational Stroke Research
The extracellular matrix fragment perlecan domain V is neuroprotective and functionally restorative following experimental stroke. As neurogenesis is an important component of chronic post-stroke repair, and previous studies have implicated perlecan
Autor:
Rahau S. Shirazi, Andrew N. Clarkson, Michelle Glass, Emma K. Gowing, Mikhail Vyssotski, Vincent Luscombe, Dion Thompson, Kirill Lagutin, D. Bradley G. Williams, Kim Parker, Christa MacDonald
Publikováno v:
LipidsREFERENCES. 57(1)
N-acylethanolamines (NAE, also called ethanolamides) are significant lipid signaling molecules with anti-inflammatory, pain-relieving, cell-protective, and anticancer properties. Here, we present the use of a hitherto unreported group of Δ3-NAE and
Publikováno v:
Neural Plasticity
Neural Plasticity, Vol 2019 (2019)
Neural Plasticity, Vol 2019 (2019)
Stroke remains a leading cause of disability worldwide. Recently, we have established an animal model of stroke that results in delayed impairment in spatial memory, allowing us to better investigate cognitive deficits. Young and aged brains show dif