Using home monitoring technology to study the effects of traumatic brain injury on older multimorbid adults: protocol for a feasibility study

Autor: Paresh Malhotra, David J Sharp, Yuchen Zhao, Michael David, David Sharp, Michael Fertleman, Lenny Naar, Sarah Daniels, Ramin Nilforooshan, Derk-Jan Dijk, Claire Norman, Greg Scott, Ian Williams, John Patterson, Neil Graham, David Wingfield, Mara Golemme, Melanie Dani, Sanara Raza, Lucia M Li, Sumit Dey, Eyal Soreq, Payam Barnaghi, Martina Del Giovane, Magdalena Kolanko, Ciro Della Monica, Helen Lai, Tong Wu, Megan E Parkinson, Danielle Wilson, Zaynab Ismail, Paul Freemont, Ravi Vaidyanathan, Tim Constandinou, Naomi Hassim, Mark Crook Rumsey, Emma Jane Mallas, Alina-Irina Serban, Alan Bannon, Shlomi Haar, Charalambos Hadjipanayi, Ghena Hammour, Bryan Hsieh, Adrien Rapeaux, Maowen Yin, Maria Lima, Maitreyee Wairagkar, Nan Fletcher-Lloyd, Hamed Haddadi, Valentinas Janeiko, Anna Joffe, Samaneh Kouchaki, Viktor Levine, Honglin Li, Amer Marzuki, Francesca Palermo, Mark Woodbridge, Alexander Capstick, Severin Skillman, Loren Cameron, Michael Crone, Kirsten Jensen, Anne Skeldon, Kevin Wells, Ullrich Bartsch, Kiran G R Kumar, Damion Lambert, Sara Mohammadi Mahvash, Thalia Rodriguez Garcia, Martin Tran, Thomas Adam, Vikki Revell, Giuseppe Atzori, Lucinda Grainger, Hana Hassanin, James Woolley, Iris Wood-Campar, Janetta Rexha, Sophie Horrocks, Brian Quan, Jessica True, Olga Balazikova, Emily Beale, Vaiva Zarombaite, Lucy Copps, Olivia Knight, Gaganpreet Bangar, Chelsea Mukonda, Jessica Hine, Luke Mallon, Anesha Patel, Ruby Lyall, Pippa Kirby, Mike Law, Andy Kenny

Publikováno v: BMJ Open, Vol 13, Iss 5 (2023)

Introduction The prevalence of traumatic brain injury (TBI) among older adults is increasing exponentially. The sequelae can be severe in older adults and interact with age-related conditions such as multimorbidity. Despite this, TBI research in olde

Externí odkaz: https://doaj.org/article/7ac3b4d583fb40b7a0a33329f530b719

The human vestibular cortex: functional anatomy of OP2, its connectivity and the effect of vestibular disease

Autor: Richard T Ibitoye, Emma-Jane Mallas, Niall J Bourke, Diego Kaski, Adolfo M Bronstein, David J Sharp

Publikováno v: Cerebral Cortex. 33:567-582

Area OP2 in the posterior peri-sylvian cortex has been proposed to be the core human vestibular cortex. We investigated the functional anatomy of OP2 and adjacent areas (OP2+) using spatially constrained independent component analysis (ICA) of functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0512d4c560395768b90966b59f3bcf0d
https://doi.org/10.1093/cercor/bhac085

Online Cognitive Assessment of Traumatic Brain Injury Patients is Accessible, Feasible and Performs Well Relative to Established Clinical

Autor: Martina Del Giovane, William Trender, Maria Bălăeţ, Emma-Jane Mallas, Amy Jolly, Niall J. Bourke, Karl Zimmermann, Neil Graham, Helen Lai, Ethan J. F. Losty, Garazi Araña Oiarbide, Peter J. Hellyer, Irene Faiman, Philippa Batey, Matthew Harrison, Valentina Giunchiglia, Magdalena Kolanko, Michael C. B. David, Lucia M. Li, Célia Demarchi, Daniel Friedland, David J. Sharp, Adam Hampshire

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de665d101abe2181cb8de07d9eb65c0a
https://doi.org/10.2139/ssrn.4352554

Genome-wide discovered psychosis-risk gene ZNF804A impacts on white matter microstructure in health, schizophrenia and bipolar disorder

Autor: Emma-Jane Mallas, Francesco Carletti, Christopher A. Chaddock, James Woolley, Marco M. Picchioni, Sukhwinder S. Shergill, Fergus Kane, Matthew P.G. Allin, Gareth J. Barker, Diana P. Prata

Publikováno v: PeerJ, Vol 4, p e1570 (2016)

Background. Schizophrenia (SZ) and bipolar disorder (BD) have both been associated with reduced microstructural white matter integrity using, as a proxy, fractional anisotropy (FA) detected using diffusion tensor imaging (DTI). Genetic susceptibility

Externí odkaz: https://doaj.org/article/80faab465d8a4e6aafc832f8a5a2bee2

Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury

Autor: Mark Wilson, Camelia Baciu, Mauro Oddo, Emma-Jane Mallas, John-Paul Miroz, David J. Sharp, Giovanni Nattino, Henrik Zetterberg, Primoz Gradisek, Amy Jolly, Amanda Heslegrave, Cornelius K. Donat, Neil S. Graham, Karl Zimmerman, Eyal Soreq, Elena Garbero, Arturo Chieregato, Guido Bertolini, Enrico Fainardi, Adriano Bernini, Samia Abed Maillard, Sandra Magnoni, Maneesh C. Patel, Niall J Bourke, Federico Moro, Maria Yanez Lopez, Gavin Fatania, Dylan Roi

Axonal injury is a key determinant of long-term outcomes after traumatic brain injury (TBI) but has been difficult to measure clinically. Fluid biomarker assays can now sensitively quantify neuronal proteins in blood. Axonal components such as neurof

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c873994bafbf5d1d1316b410894e23b
http://hdl.handle.net/10044/1/91900