Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Emma J. McGhie"'
Autor:
David M Bulmer, Lubna Kharraz, Andrew J Grant, Paul Dean, Fiona J E Morgan, Michail H Karavolos, Anne C Doble, Emma J McGhie, Vassilis Koronakis, Richard A Daniel, Pietro Mastroeni, C M Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://doaj.org/article/0e54051753e7417a9ab0ff1ecf95a74a
Autor:
Kenneth G Campellone, Hui-Chun Cheng, Douglas Robbins, Anosha D Siripala, Emma J McGhie, Richard D Hayward, Matthew D Welch, Michael K Rosen, Vassilis Koronakis, John M Leong
Publikováno v:
PLoS Pathogens, Vol 4, Iss 10, p e1000191 (2008)
Enterohemorrhagic Escherichia coli (EHEC) generate F-actin-rich adhesion pedestals by delivering effector proteins into mammalian cells. These effectors include the translocated receptor Tir, along with EspF(U), a protein that associates indirectly w
Externí odkaz:
https://doaj.org/article/1833dccf93e843dd9eeb6550fce9fe1c
Autor:
Michail H. Karavolos, Pietro Mastroeni, Lubna Kharraz, David M. Bulmer, Emma J. McGhie, Fiona J. E. Morgan, Paul Dean, Andrew J. Grant, Anne C. Doble, Vassilis Koronakis, Richard A. Daniel, C. M. Anjam Khan
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)
PLoS Pathogens
PLoS Pathogens
Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c9c9b343cebceab62e914a8246c9d8
Autor:
Michail N. Isupov, Ewald Schröder, Robert P. Gibson, Jean Beecher, Giuliana Donadio, Vahid Saneei, Stephlina A. Dcunha, Emma J. McGhie, Christopher Sayer, Colin F. Davenport, Peter C. K. Lau, Yoshie Hasegawa, Hiroaki Iwaki, Maria Kadow, Kathleen Balke, Uwe T. Bornscheuer, Gleb Bourenkov, Jennifer A. Littlechild
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
The first crystal structure of a type II Baeyer–Villiger monooxygenase reveals a different ring orientation of its FMN cofactor compared with other related bacterial luciferase-family enzymes.
The three-dimensional structures of the native enz
The three-dimensional structures of the native enz
Autor:
Peter C. K. Lau, Maria Kadow, Ewald Schröder, Yoshie Hasegawa, Colin F. Davenport, Robert P. Gibson, Michail N. Isupov, Uwe T. Bornscheuer, Hiroaki Iwaki, Gleb Bourenkov, Emma J. McGhie, C. Sayer, Jennifer A. Littlechild, Vahid Saneei, Stephlina A. Dcunha, Kathleen Balke, Jean Beecher, Giuliana Donadio
The three-dimensional structures of the native enzyme and the FMN complex of the overexpressed form of the oxygenating component of the type II Baeyer–Villiger 3,6-diketocamphane monooxygenase have been determined to 1.9 Å resolution. The structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa144fa1c8813760ab2ed1108cd1cf0
https://doi.org/10.1107/s1399004715017939
https://doi.org/10.1107/s1399004715017939
Autor:
Neil Phillips, Matthew J. Garner, Robert J. Cain, Richard D. Hayward, Emma J. McGhie, Vassilis Koronakis
Publikováno v:
Molecular Microbiology. 56:590-603
A ubiquitous early step in infection of man and animals by enteric bacterial pathogens like Salmonella, Shigella and enteropathogenic Escherichia coli (EPEC) is the translocation of virulence effector proteins into mammalian cells via specialized typ
Publikováno v:
Molecular Cell. 13(4):497-510
Salmonella force their way into nonphagocytic host intestinal cells to initiate infection. Uptake is triggered by delivery into the target cell of bacterial effector proteins that stimulate cytoskeletal rearrangements and membrane ruffling. The Salmo
Publikováno v:
Molecular Microbiology. 49:425-439
An essential early event in Shigella and Salmonella pathogenesis is invasion of non-phagocytic intestinal epithelial cells. Pathogen entry is triggered by the delivery of multiple bacterial effector proteins into target mammalian cells. The Shigella
Publikováno v:
Molecular Microbiology. 45:1715-1727
Entry into non-phagocytic mammalian cells by the invasive pathogens Salmonella and Shigella is triggered by the delivery of bacterial virulence effector proteins into the host cell. This is dependent upon Salmonella SipB or its Shigella homologue Ipa
Publikováno v:
Molecular Microbiology. 44:1309-1321
Summary A critical early event in Salmonella infection is entry into intestinal epithelial cells. The Salmonella inva- sion protein SipB is required for the delivery of bacterial effector proteins into target eukaryotic cells, which subvert signal tr