Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Emma J. Collings"'
Autor:
Julie Hawkins, Barry Sidney Orlek, Graham J. Riley, Emma J. Collings, Richard E. Faulkner, Frederick Cassidy, Michael S. G. Clark
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1411-1414
Replacement of the ester group in methyl quinuclidine-3-car☐ylate1 with a 1,2,4-triazine ring afforded the high affinity muscarinic partial agonist6a. Analogues7a,7b and7d which incorporate the 1-azabicyclo[2.2.1]heptane ring also display high affi
Autor:
Barry Sidney Orlek, Graham J. Riley, Richard E. Faulkner, Steven Mark Bromidge, Frank Brown, Michael S. G. Clark, Frederick Cassidy, Loudon Julia Mary, Steven Dabbs, Emma J. Collings
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:557-562
The combination of N-methoxy imidoyl halide and nitrile moieties with the 1,2,5,6-tetrahydropyridine ring system afforded a novel series of potent muscarinic agonists. Members of this class, exemplified by the imidoyl nitriles 2c and 3c , show favour
Autor:
Frank Brown, Steven Mark Bromidge, Graham J. Riley, Emma J. Collings, Loudon Julia Mary, Barry Sidney Orlek, Richard E. Faulkner, Frederick Cassidy, Michael S. G. Clark, Steven Dabbs
Publikováno v:
ChemInform. 25
The combination of N-methoxy imidoyl halide and nitrile moieties with the 1,2,5,6-tetrahydropyridine ring system afforded a novel series of potent muscarinic agonists. Members of this class, exemplified by the imidoyl nitriles 2c and 3c , show favour
Autor:
Emma J. Collings, Graham J. Riley, Michael S. G. Clark, Frederick Cassidy, Julie Hawkins, Barry Sidney Orlek, Richard E. Faulkner
Publikováno v:
ChemInform. 25
Replacement of the ester group in methyl quinuclidine-3-car☐ylate1 with a 1,2,4-triazine ring afforded the high affinity muscarinic partial agonist6a. Analogues7a,7b and7d which incorporate the 1-azabicyclo[2.2.1]heptane ring also display high affi