Výsledky vyhledávání - "Emma J Mickley"

Localization and function of ET-1 and ET receptors in small arteries post-myocardial infarction: Upregulation of smooth muscle ETB receptors that modulate contraction

Autor: Emma J Mickley, Gillian A. Gray, Pauline E. McEwan, David J. Webb

Publikováno v: British Journal of Pharmacology. 130:1735-1744

Endothelin-1 (ET-1) has been implicated as a mediator of increased vascular tone during development of heart failure post-myocardial infarction (MI). In the present study, expression and pharmacology of ET-1 and its receptors were studied in small me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ad4223a808eb188f1007fb306ab511a
https://doi.org/10.1038/sj.bjp.0703503

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Activation of endothelin ETA receptors masks the constrictor role of endothelin ETB receptors in rat isolated small mesenteric arteries

Autor: David J. Webb, Emma J. Mickley, Gillian A. Gray

Publikováno v: British Journal of Pharmacology. 120:1376-1382

1. Endothelin-1 (ET-1) produces constriction of the rat mesenteric vascular bed in vivo via ETA and ETB receptor subtypes. The aim of this study was to investigate the relative roles of these receptor subtypes in rat isolated, endothelium-denuded, sm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f5de0261a634088297957b74ce34dcb
https://doi.org/10.1038/sj.bjp.0701036

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Characterization of endothelin receptors mediating the effects of the endothelin/sarafotoxin peptides on autonomic neurotransmission in the rat vas deferens and guinea-pig ileum

Autor: John R. Vane, Graham H. Allcock, Emma J. Mickley, Timothy D. Warner

Publikováno v: British Journal of Pharmacology. 110:783-789

1. To characterize the receptors mediating the effects of the endothelin/sarafotoxin family of peptides on the responses to electrical stimulation of the rat vas deferens (RVD) and guinea-pig ileum (GPI) we have used endothelin-1 (ET-1), ET-3, sarafo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caeefa1d0174827fd0de066a3e5f8669
https://doi.org/10.1111/j.1476-5381.1993.tb13880.x

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Comparative Studies with the Endothelin Receptor Antagonists BQ-123 and PD 142893 Indicate At Least Three Endothelin Receptors

Autor: Timothy D. Warner, Roger Corder, John R. Vane, Graham H. Allcock, Emma J. Mickley

Publikováno v: Journal of Cardiovascular Pharmacology. 22:S117-S120

Endothelin-1 (ET-1), endothelin-3 (ET-3), sarafotoxin 6b (SX6b), and sarafotoxin 6C (SX6c) were used as agonists, and BQ-123 (ETA-selective) and PD 142893 (ET receptor-nonselective) were used as antagonists to characterize the receptors mediating the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369c6d1a351720df0b7481223f18f893
https://doi.org/10.1097/00005344-199322008-00032

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