Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Emma Guttman‐Yassky"'
Autor:
Matthew P. Kosloski, Emma Guttman‐Yassky, Michael J. Cork, Margitta Worm, Dong‐Ho Nahm, Xiaoping Zhu, Marcella K. Ruddy, Sivan Harel, Mohamed A. Kamal, Hélène Goulaouic, Christine R. Xu, Elena Avetisova, John D. Davis, Michael C. Nivens, Arsalan Shabbir, Allen Radin
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 8, Pp n/a-n/a (2024)
Abstract Interleukin‐33 (IL‐33) is a proinflammatory alarmin cytokine released by damaged epithelial tissue cells that initiates and amplifies both type 1 and type 2 inflammatory cascades. A role for IL‐33 in atopic dermatitis (AD; a chronic, r
Externí odkaz:
https://doaj.org/article/574d478bee6847e5989bba493bdec8fc
Autor:
Melinda J. Gooderham, Michael R. Ardern‐Jones, Emma Guttman‐Yassky, Mahreen Ameen, Eric L. Simpson, Gary Chan, Pinaki Biswas, Wing S. Chiu, Melissa Watkins
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 4, Pp 753-763 (2023)
Abstract Background Patients with moderate‐to‐severe atopic dermatitis (AD) refractory to topical therapy might require treatment with systemic therapies, including biologics. Objectives To assess the efficacy and safety of abrocitinib monotherap
Externí odkaz:
https://doaj.org/article/f7c8551174694873b56769ea8f6eb795
Autor:
Jade N. Young, BS, Hannah Verma, BA, Nour El Kashlan, MD, Dina Poplausky, BA, Angela J. Lamb, MD, Emma Guttman-Yassky, MD, PhD, Nicholas Gulati, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 43, Iss , Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/fc20617a98f647fb9bfa1b9d3218e5cc
Autor:
Peter Nash, Atul Deodhar, Philip J Mease, Yoshiya Tanaka, Tim Shaw, Gerd R Burmester, Kevin L Winthrop, Alan D Irvine, Eduardo Mysler, Stanley B Cohen, Ana P Lacerda, John Liu, Hannah Palac, Emma Guttman‑Yassky
Publikováno v:
RMD Open, Vol 9, Iss 1 (2023)
Objective To evaluate the long-term safety profile for upadacitinib across rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS) and atopic dermatitis (AD).Methods Safety data from clinical trials of upadacitinib 15 mg and
Externí odkaz:
https://doaj.org/article/0a14bda1c5df487ca97dad80e6cdb1e7
Autor:
Brett King, Emma Guttman-Yassky, Elena Peeva, Anindita Banerjee, Linda Zhu, Hua Zhu, Lori Ann Cox, Michael S. Vincent, Rodney Sinclair
Publikováno v:
JID Innovations, Vol 2, Iss 6, Pp 100156- (2022)
The 24-week, double-blind period of the ALLEGRO phase 2a trial (NCT02974868) evaluated the safety and efficacy of ritlecitinib (Jak3/tyrosine kinase expressed in the hepatocellular carcinoma inhibitor) and brepocitinib (tyrosine kinase 2/Jak1 inhibit
Externí odkaz:
https://doaj.org/article/0116e2d715b245428d9d62d101f6f5d4
Autor:
Mary Elizabeth Mathyer, Erin A. Brettmann, Alina D. Schmidt, Zane A. Goodwin, Inez Y. Oh, Ashley M. Quiggle, Eric Tycksen, Natasha Ramakrishnan, Scot J. Matkovich, Emma Guttman-Yassky, John R. Edwards, Cristina de Guzman Strong
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Selection on alleles contributing to human evolution is not well understood. Here, the authors investigate positive selection on skin barrier adaptation, identifying a selective sweep on involucrin alleles associated with migration out of Africa, and
Externí odkaz:
https://doaj.org/article/562d1faba6444cc8a292faa17015f06a
Autor:
Anne Weiss, Emilie Delavenne, Carina Matias, Heimo Lagler, Daniel Simon, Ping Li, Jon U. Hansen, Teresa Pires dosSantos, Bimal Jana, Petra Priemel, Christine Bangert, Martin Bauer, Sabine Eberl, Alina Nussbaumer‐Pröll, Zoe Anne Österreicher, Peter Matzneller, Tamara Quint, Maria Weber, Hanne Mørck Nielsen, Thomas Rades, Helle Krogh Johansen, Henrik Westh, Wooseong Kim, Eleftherios Mylonakis, Christian Friis, Luca Guardabassi, John Pace, Carina Vingsbo Lundberg, Fatima M'Zali, Pascal Butty, Nikolaj Sørensen, Henrik Bjørn Nielsen, Rasmus Toft‐Kehler, Emma Guttman‐Yassky, Georg Stingl, Markus Zeitlinger, Morten Sommer
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)
Abstract Background In patients with atopic dermatitis (AD), Staphylococcus aureus frequently colonizes lesions and is hypothesized to be linked to disease severity and progression. Treatments that reduce S. aureus colonization without significantly
Externí odkaz:
https://doaj.org/article/c12af968bd3a4c4badc928f617fc3d24
Autor:
Bruno Falissard, Eric L. Simpson, Emma Guttman-Yassky, Kim A. Papp, Sebastien Barbarot, Abhijit Gadkari, Grece Saba, Laurene Gautier, Adeline Abbe, Laurent Eckert
Publikováno v:
Dermatology and Therapy, Vol 10, Iss 2, Pp 307-310 (2020)
The authors would like to correct the images in figures which are in wrong order and require swapping.
Externí odkaz:
https://doaj.org/article/4fe4c14e97f24fc788a8df03602e9bf0
Autor:
Bruno Falissard, Eric L. Simpson, Emma Guttman-Yassky, Kim A. Papp, Sebastien Barbarot, Abhijit Gadkari, Grece Saba, Laurene Gautier, Adeline Abbe, Laurent Eckert
Publikováno v:
Dermatology and Therapy, Vol 10, Iss 2, Pp 297-305 (2020)
Abstract Introduction Atopic dermatitis (AD) is an incurable, inflammatory skin disease characterized by skin barrier disruption and immune dysregulation. Although AD is considered a childhood disease, adult onset is possible, presenting with daily s
Externí odkaz:
https://doaj.org/article/d7f2497172b147799870d720575581cd
Autor:
Teruki Dainichi, Yuri Nakano, Hiromi Doi, Satoshi Nakamizo, Saeko Nakajima, Reiko Matsumoto, Thomas Farkas, Pui Mun Wong, Vipin Narang, Ricardo Moreno Traspas, Eiryo Kawakami, Emma Guttman-Yassky, Oliver Dreesen, Thomas Litman, Bruno Reversade, Kenji Kabashima
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The epidermis, outermost layer of the skin, forms a barrier and is involved in innate and adaptive immunity in an organism. Keratinocytes participate in all these three protective processes. However, a regulator of keratinocyte protective responses a
Externí odkaz:
https://doaj.org/article/edd5f834c33541978485b78d10437417