Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Emma Gostick"'
Autor:
Caroline Passaes, Antoine Millet, Vincent Madelain, Valérie Monceaux, Annie David, Pierre Versmisse, Naya Sylla, Emma Gostick, Sian Llewellyn-Lacey, David A. Price, Antoine Blancher, Nathalie Dereuddre-Bosquet, Delphine Desjardins, Gianfranco Pancino, Roger Le Grand, Olivier Lambotte, Michaela Müller-Trutwin, Christine Rouzioux, Jérémie Guedj, Véronique Avettand-Fenoel, Bruno Vaslin, Asier Sáez-Cirión
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108174- (2020)
Summary: Highly efficient CD8+ T cells are associated with natural HIV control, but it has remained unclear how these cells are generated and maintained. We have used a macaque model of spontaneous SIVmac251 control to monitor the development of effi
Externí odkaz:
https://doaj.org/article/d5d9b827951c4bedb5f5b3b7eaad4b58
Autor:
Morgan A. Reuter, Perla M. Del Rio Estrada, Marcus Buggert, Constantinos Petrovas, Sara Ferrando-Martinez, Son Nguyen, Alberto Sada Japp, Yuria Ablanedo-Terrazas, Amaranta Rivero-Arrieta, Leticia Kuri-Cervantes, Heidi M. Gunzelman, Emma Gostick, David A. Price, Richard A. Koup, Ali Naji, David H. Canaday, Gustavo Reyes-Terán, Michael R. Betts
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3458-3470 (2017)
Summary: Elimination of lymphoid tissue reservoirs is a key component of HIV eradication strategies. CD8+ T cells play a critical role in control of HIV, but their functional attributes in lymph nodes (LNs) remain unclear. Here, we show that memory,
Externí odkaz:
https://doaj.org/article/6bc44c6e41074190a760d0bb474a3be4
Autor:
Francesco Nicoli, Laura Papagno, Justin J. Frere, Mariela Pires Cabral-Piccin, Emmanuel Clave, Emma Gostick, Antoine Toubert, David A. Price, Antonella Caputo, Victor Appay
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Characterization of the intracellular biochemical processes that regulate the generation and maintenance of effector and memory CD8+ T-cells from naïve precursors is essential for our understanding of adaptive immune responses and the de
Externí odkaz:
https://doaj.org/article/af66cabcde484e6c9e8283c11d8dcbba
Autor:
Corey Smith, Victor Lee, Andrea Schuessler, Leone Beagley, Sweera Rehan, Janice Tsang, Vivian Li, Randal Tiu, David Smith, Michelle A. Neller, Katherine K. Matthews, Emma Gostick, David A. Price, Jacqueline Burrows, Glen M. Boyle, Daniel Chua, Benedict Panizza, Sandro V. Porceddu, John Nicholls, Dora Kwong, Rajiv Khanna
Publikováno v:
OncoImmunology, Vol 6, Iss 2 (2017)
Adoptive T cell therapy has emerged as a powerful strategy to treat human cancers especially haematological malignancies. Extension of these therapies to solid cancers remains a significant challenge especially in the context of defining immunologica
Externí odkaz:
https://doaj.org/article/0d074c6887494e51b57d37814a7a23d1
Autor:
Natalija Budimir, Aalzen de Haan, Tjarko Meijerhof, Simke Waijer, Louis Boon, Emma Gostick, David A Price, Jan Wilschut, Anke Huckriede
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63163 (2013)
Current influenza vaccines fail to induce protection against antigenically distinct virus strains. Accordingly, there is a need for the development of cross-protective vaccines. Previously, we and others have shown that vaccination with whole inactiv
Externí odkaz:
https://doaj.org/article/7f9759a548894f2180e67579b2ec157b
Autor:
Julia Schmidt, Astrid K N Iversen, Stefan Tenzer, Emma Gostick, David A Price, Volker Lohmann, Ute Distler, Paul Bowness, Hansjörg Schild, Hubert E Blum, Paul Klenerman, Christoph Neumann-Haefelin, Robert Thimme
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003042 (2012)
HLA-B*27 exerts protective effects in hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections. While the immunological and virological features of HLA-B*27-mediated protection are not fully understood, there is growing evidence that
Externí odkaz:
https://doaj.org/article/c948d12be085467aa0d4b5ccb27562d4
Autor:
Natalija Budimir, Anke Huckriede, Tjarko Meijerhof, Louis Boon, Emma Gostick, David A Price, Jan Wilschut, Aalzen de Haan
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30898 (2012)
BACKGROUND: The inability of seasonal influenza vaccines to effectively protect against infection with antigenically drifted viruses or newly emerging pandemic viruses underlines the need for development of cross-reactive influenza vaccines that indu
Externí odkaz:
https://doaj.org/article/19ad40b9d2e5421fa8d48051ec3db34e
Autor:
Tracy J Ruckwardt, Allison M W Malloy, Emma Gostick, David A Price, Pradyot Dash, Jennifer L McClaren, Paul G Thomas, Barney S Graham
Publikováno v:
PLoS Pathogens, Vol 7, Iss 12, p e1002377 (2011)
Following respiratory syncytial virus infection of adult CB6F1 hybrid mice, a predictable CD8+ T cell epitope hierarchy is established with a strongly dominant response to a K(d)-restricted peptide (SYIGSINNI) from the M2 protein. The response to K(d
Externí odkaz:
https://doaj.org/article/55ead976929548608b5098c3ade7544c
Autor:
Lara Vojnov, Mauricio A Martins, Jorge R Almeida, Zachary Ende, Eva G Rakasz, Matthew R Reynolds, Enrique J Leon, Kim L Weisgrau, Benjamin J Burwitz, Joy M Folkvord, Marlon G Veloso de Santana, Patrícia C Costa Neves, Elizabeth Connick, Pamela J Skinner, Emma Gostick, David H O'Connor, Nancy A Wilson, Myrna C Bonaldo, Ricardo Galler, David A Price, Danny C Douek, David I Watkins
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23515 (2011)
Several lines of evidence suggest that HIV/SIV-specific CD8(+) T cells play a critical role in the control of viral replication. Recently we observed high levels of viremia in Indian rhesus macaques vaccinated with a segment of SIVmac239 Gag (Gag(45-
Externí odkaz:
https://doaj.org/article/7194b0666af841749b79ab89ca7b9445
Autor:
John J Miles, Anna M Bulek, David K Cole, Emma Gostick, Andrea J A Schauenburg, Garry Dolton, Vanessa Venturi, Miles P Davenport, Mai Ping Tan, Scott R Burrows, Linda Wooldridge, David A Price, Pierre J Rizkallah, Andrew K Sewell
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001198 (2010)
Despite the ∼10(18) αβ T cell receptor (TCR) structures that can be randomly manufactured by the human thymus, some surface more frequently than others. The pinnacles of this distortion are public TCRs, which exhibit amino acid-identical structur
Externí odkaz:
https://doaj.org/article/306c4ef650b24c9d8ee4fe6f2fc17f93