Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Emma Fiorini"'
Autor:
Cassia Overk, Emma Fiorini, Chiara Babolin, Marija Vukicevic, Catherine Morici, Rime Madani, Valerie Eligert, Marie Kosco-Vilbois, Amanda Roberts, Ann Becker, Andrea Pfeifer, William C. Mobley
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionPeople with DS are highly predisposed to Alzheimer’s disease (AD) and demonstrate very similar clinical and pathological features. Ts65Dn mice are widely used and serve as the best-characterized animal model of DS.MethodsWe undertook st
Externí odkaz:
https://doaj.org/article/7e7e2a8942f745cbb81e9ba1997aa1c8
Autor:
Jasenka Rudan Njavro, Marija Vukicevic, Emma Fiorini, Lina Dinkel, Stephan A. Müller, Anna Berghofer, Chiara Bordier, Stanislav Kozlov, Annett Halle, Katrin Buschmann, Anja Capell, Camilla Giudici, Michael Willem, Regina Feederle, Stefan F. Lichtenthaler, Chiara Babolin, Paolo Montanari, Andrea Pfeifer, Marie Kosco-Vilbois, Sabina Tahirovic
Publikováno v:
Cells, Vol 12, Iss 1, p 79 (2022)
Amyloid-β (Aβ) deposition is an initiating factor in Alzheimer’s disease (AD). Microglia are the brain immune cells that surround and phagocytose Aβ plaques, but their phagocytic capacity declines in AD. This is in agreement with studies that as
Externí odkaz:
https://doaj.org/article/edb55993cf0641deb58d04ca6445fe92
Autor:
Emma Fiorini, Pier Carlo Marchisio, Maria Teresa Scupoli, Ornella Poffe, Elda Tagliabue, Monica Brentegani, Marco Colombatti, Franscesco Santini, Giuseppe Tridente, Dunia Ramarli
Publikováno v:
Clinical and Developmental Immunology, Vol 7, Iss 2-4, Pp 195-208 (2000)
Externí odkaz:
https://doaj.org/article/b08d02a5116243a79af74d865bac509a
Autor:
Emma Fiorini, Marija Vukicevic, Rakel Carpintero, Marcela Rincon, Pilar Lopez‐Deber, Nicolas Piot, Maxime Ayer, Inmaculada Rentero, Stefanie Siegert, Chiara Babolin, Delphine Knittel, Eva Gollwitzer, Sophie Bravo‐Veyrat, Valérie Giriens, Catherine Morici, Marie‐Gabrielle Beuzelin, Anthony Gesbert, Sebastien Rivot, Nathalie Chuard, Vanessa Attanasio, Saskia Delpretti, Piergiorgio Donati, Johannes Streffer, Andrea Pfeifer, Marie Kosco‐Vilbois
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Andreas Muhs, Maria Pihlgren, Emma Fiorini, Andrea Pfeifer, Nathalie Chuard, Delphine Knittel, Valérie Giriens, Marija Vukicevic
Publikováno v:
Alzheimer's & Dementia. 13
Autor:
Sanjiv A. Luther, Emma Fiorini, Caroline Poisson, H. Robson MacDonald, Isabel Ferrero, Leonardo Scarpellino
Publikováno v:
genesis. 51:717-724
The thymus is the site of T cell development. Several stromal and hematopoietic cell types are necessary for the proper function of thymic selection and eventually peripheral immunity. Thymic epithelial cells (TECs) are essential for T cell lineage c
Autor:
Nagisa Sakurai, Takahiro Maeda, Sung-Uk Lee, Manami Maeda, Freddy Radtke, H. Robson MacDonald, Adrian M. Jubb, Minhong Yan, Ching-Cheng Chen, Sierra Min Li, Anne Wilson, Lihong Weng, Emma Fiorini, Yuichi Ishikawa
Publikováno v:
Blood
Hematopoietic stem cells (HSCs) are the most primitive cells in the hematopoietic system and are under tight regulation for self-renewal and differentiation. Notch signals are essential for the emergence of definitive hematopoiesis in mouse embryos a
Publikováno v:
The Journal of Neuroscience. 32:5654-5666
The adult mammalian forebrain contains neural stem/progenitor cells (NSCs) that generate neurons throughout life. As in other somatic stem cell systems, NSCs are proposed to be predominantly quiescent and proliferate only sporadically to produce more
Publikováno v:
European Journal of Immunology. 37:3220-3228
Although it is well established that early expression of TCRbeta transgenes in the thymus leads to efficient inhibition of both endogenous TCRbeta and TCRgamma rearrangement (also known as allelic and "isotypic" exclusion, respectively) the role of p
Autor:
Doreen A. Cantrell, April P. Kelly, Rosie G Clarke, Freddy Radtke, David K. Finlay, Emma Fiorini, Heather J. Hinton
Publikováno v:
The EMBO Journal
EMBO Journal, vol. 26, no. 14, pp. 3441-50
EMBO Journal, vol. 26, no. 14, pp. 3441-50
Phosphoinositide-dependent kinase l (PDK1) phosphorylates and activates multiple AGC serine kinases, including protein kinase B (PKB), p70Ribosomal S6 kinase (S6K) and p90Ribosomal S6 kinase (RSK). PDK1 is required for thymocyte differentiation and p