Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Emma E Thompson"'
Autor:
Matthew Dapas, Emma E Thompson, William Wentworth-Sheilds, Selene Clay, Cynthia M Visness, Agustin Calatroni, Joanne E Sordillo, Diane R Gold, Robert A Wood, Melanie Makhija, Gurjit K Khurana Hershey, Michael G Sherenian, Rebecca S Gruchalla, Michelle A Gill, Andrew H Liu, Haejin Kim, Meyer Kattan, Leonard B Bacharier, Deepa Rastogi, Matthew C Altman, William W Busse, Patrice M Becker, Dan Nicolae, George T O'Connor, James E Gern, Daniel J Jackson, Carole Ober
Publikováno v:
PLoS Genetics, Vol 19, Iss 1, p e1010594 (2023)
Impaired lung function in early life is associated with the subsequent development of chronic respiratory disease. Most genetic associations with lung function have been identified in adults of European descent and therefore may not represent those m
Externí odkaz:
https://doaj.org/article/d10dc071b47a4cef941d868fd30e4720
Autor:
Marcus M. Soliai, Atsushi Kato, Britney A. Helling, Catherine T. Stanhope, James E. Norton, Katherine A. Naughton, Aiko I. Klinger, Emma E. Thompson, Selene M. Clay, Soyeon Kim, Juan C. Celedón, James E. Gern, Daniel J. Jackson, Matthew C. Altman, Robert C. Kern, Bruce K. Tan, Robert P. Schleimer, Dan L. Nicolae, Jayant M. Pinto, Carole Ober
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-22 (2021)
Abstract Background Genome-wide association studies (GWASs) have identified thousands of variants associated with asthma and other complex diseases. However, the functional effects of most of these variants are unknown. Moreover, GWASs do not provide
Externí odkaz:
https://doaj.org/article/4801d6bd42fb43bfb87a30cdbaaf0ea9
Autor:
Michelle M. Stein, Mitch Conery, Kevin M. Magnaye, Selene M. Clay, Christine Billstrand, Raluca Nicolae, Katherine Naughton, Carole Ober, Emma E. Thompson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Sex-specific differences in prevalence are well documented for many common, complex diseases, especially for immune-mediated diseases, yet the precise mechanisms through which factors associated with biological sex exert their effects throug
Externí odkaz:
https://doaj.org/article/ba1b370061be4fbe9a9e6a4402d39e72
Autor:
Emma E. Thompson, Quynh Dang, Blair Mitchell-Handley, Kavitha Rajendran, Sumati Ram-Mohan, Julian Solway, Carole Ober, Ramaswamy Krishnan
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-14 (2020)
Abstract Background A challenge in the post-GWAS era is to assign function to disease-associated variants. However, available resources do not include all tissues or environmental exposures that are relevant to all diseases. For example, exaggerated
Externí odkaz:
https://doaj.org/article/37452189b587449ab05b8f54a59cf4b4
Autor:
Emma E. Thompson, Jessie Nicodemus-Johnson, Kyung Won Kim, James E. Gern, Daniel J. Jackson, Robert F. Lemanske, Carole Ober
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background The changes that occur during puberty have been implicated in susceptibility to a wide range of diseases later in life, many of which are characterized by sex-specific differences in prevalence. Both genetic and environmental fact
Externí odkaz:
https://doaj.org/article/87c7f3952723442893fa3df535cc3427
Autor:
Federico Innocenti, Kurt Ballmer-Hofer, Rafal Dziadziuszko, Fred R. Hirsch, Ravi Salgia, Mark W. Lingen, Witold Rzyman, Jacek Jassem, Soma Das, Peixian Chen, Emma E. Thompson, Osman Mirza, Wei Zhang, Alexandra Giese, Elisa Cerri, Dylan M. Glubb
PDF file - 102K, Summary of KDR genetic variant found after resequencing of 72 healthy subjects of three different ethnicities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16a899023926d33472ebef315cbba7b
https://doi.org/10.1158/1078-0432.22444608
https://doi.org/10.1158/1078-0432.22444608
Autor:
Federico Innocenti, Kurt Ballmer-Hofer, Rafal Dziadziuszko, Fred R. Hirsch, Ravi Salgia, Mark W. Lingen, Witold Rzyman, Jacek Jassem, Soma Das, Peixian Chen, Emma E. Thompson, Osman Mirza, Wei Zhang, Alexandra Giese, Elisa Cerri, Dylan M. Glubb
PDF file - 46K, KDR regions containing dense clusters of transcription factor binding motifs identified by Cluster-Buster.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cdae47e2052e00b2345a9c67e06eb0
https://doi.org/10.1158/1078-0432.22444614
https://doi.org/10.1158/1078-0432.22444614
Autor:
Federico Innocenti, Kurt Ballmer-Hofer, Rafal Dziadziuszko, Fred R. Hirsch, Ravi Salgia, Mark W. Lingen, Witold Rzyman, Jacek Jassem, Soma Das, Peixian Chen, Emma E. Thompson, Osman Mirza, Wei Zhang, Alexandra Giese, Elisa Cerri, Dylan M. Glubb
PDF file - 26K, Correlation of VEGFR-2 and KDR mRNA levels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5631807777c9457686a8c8fe327412d1
https://doi.org/10.1158/1078-0432.22444632.v1
https://doi.org/10.1158/1078-0432.22444632.v1
Autor:
Federico Innocenti, Kurt Ballmer-Hofer, Rafal Dziadziuszko, Fred R. Hirsch, Ravi Salgia, Mark W. Lingen, Witold Rzyman, Jacek Jassem, Soma Das, Peixian Chen, Emma E. Thompson, Osman Mirza, Wei Zhang, Alexandra Giese, Elisa Cerri, Dylan M. Glubb
PDF file - 60K, KDR conserved regions determined using comparative genomics analysis in the UCSC Genome Browser.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e085e6ae24485ff4a4dfc9cc92cf1a3
https://doi.org/10.1158/1078-0432.22444617
https://doi.org/10.1158/1078-0432.22444617
Autor:
Federico Innocenti, Kurt Ballmer-Hofer, Rafal Dziadziuszko, Fred R. Hirsch, Ravi Salgia, Mark W. Lingen, Witold Rzyman, Jacek Jassem, Soma Das, Peixian Chen, Emma E. Thompson, Osman Mirza, Wei Zhang, Alexandra Giese, Elisa Cerri, Dylan M. Glubb
PDF file - 94K, Bioinformatic analyses of the putative functional effects of KDR genetic variants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bfa778008263fd4fd16cffb72797e1
https://doi.org/10.1158/1078-0432.22444605
https://doi.org/10.1158/1078-0432.22444605