Ectopic ACTH Secretion Secondary to Metastatic Acinic Cell Carcinoma of the Parotid Gland: A Case Report and Review of Current Evidence for Systemic Therapy

Autor: Louise Wade MBChB, Paul Kitching MB BCh, FRCPath, Emma De Winton MBBS, FRCR

Publikováno v: Journal of Investigative Medicine High Impact Case Reports, Vol 8 (2020)

Acinic cell carcinoma is a rare, typically indolent, neoplasm that arises in the salivary glands. Metastatic disease is uncommon, occurring in around 10% of cases. We report the case of a 46-year-old male in whom the first sign of disseminated diseas

Externí odkaz: https://doaj.org/article/d2342b01076d43f5b328aa35caaeff28

Inhibition of WEE1 Is Effective in

Autor: Jenny F, Seligmann, David J, Fisher, Louise C, Brown, Richard A, Adams, Janet, Graham, Philip, Quirke, Susan D, Richman, Rachel, Butler, Enric, Domingo, Andrew, Blake, Emma, Yates, Michael, Braun, Fiona, Collinson, Rob, Jones, Ewan, Brown, Emma, de Winton, Timothy C, Humphrey, Mahesh, Parmar, Richard, Kaplan, Richard H, Wilson, Matthew, Seymour, Timothy S, Maughan

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39(33)

Outcomes inPatients with newly diagnosed mCRC were registered into FOCUS4 and tested forFOCUS4-C was conducted between April 2017 and Mar 2020 during which time 718 patients were registered; 247 (34%) wereIn this phase II randomized trial, adavoserti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fbc8e57d310ea2157e506e12303c932
https://pubmed.ncbi.nlm.nih.gov/34538072

A multi-centre survey reveals variations in the standard treatments and treatment modifications for head and neck cancer patients during Covid-19 pandemic

Autor: Matthew Griffin, A. Michaelidou, Niveditha Singh, Paul Sanghera, Petra Jankowska, Laura Pettit, Emma De Winton, L. O'Toole, Konstantinos Geropantas, S.A. Bhide, Rafael Moleron, Mano Joseph, S. Schipani, Anthony Kong Conceptualisation, Ifigenia Vasiliadou, B. Foran, Teresa Guerrero Urbano, Andrew Hartley, David Noble, Kannon Nathan, Rebecca Goranova, Dorothy M. Gujral, Jonathan Chambers, Mehmet Sen, Ketan A. Shah, Anoop Haridass

Publikováno v: Clinical and Translational Radiation Oncology
Clinical and Translational Radiation Oncology, Vol 30, Iss, Pp 50-59 (2021)
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY

Background The onset of the COVID-19 pandemic necessitated rapid changes to the practice of head and neck oncology in UK. There was a delay between the onset of the pandemic and the release of guidelines from cancer societies and networks, leading to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c37f7e9a330762b048b6dba192b386
https://pubmed.ncbi.nlm.nih.gov/34226880

Non-invasive ventilation for a rapidly deteriorating palliative patient

Autor: Louisa Stockton, Elizabeth Green, Emma De Winton

Publikováno v: BMJ Supportive & Palliative Care. 9:226-228

Non-invasive ventilation (NIV) is a further option for oxygen delivery to an acutely unwell patient. However it is often overlooked as a tool within palliation. We report a case of a young woman presenting in extremis with type 1 respiratory failure.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4f8a34859ac95a5c47bb8e396ffdff
https://doi.org/10.1136/bmjspcare-2018-001528

Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicentre, open-label, phase 3, randomised controlled trial

Autor: N. Panakis, M. Button, James Gildersleve, Y. C. Gary Lee, Emma De Winton, Muthukumar Dakshinamoorthy, Anthony L Kerry, Samuel A. Stewart, Anna J Morley, J Pepperell, Lee Dobson, Timothy J.P. Batchelor, Samantha Cooper, Conrad R. Lewanski, Alina Ionescu, Erika Penz, Natalie Zahan-Evans, Peter Jenkins, Hazel Taylor, Timothy Howell, Charles Comins, Adrian Marchbank, M. Bayne, Nick A Maskell, Fiona McDonald, Vallipuram Vigneswaran, Najib M. Rahman, Elizabeth Toy, Lesley Bishop, Sarah Smith, Merina Ahmed, P. T. Wilson, Amelia O Clive, Nikki Jordan

Publikováno v: Clive, A O, Taylor, H, Dobson, L, Wilson, P, de Winton, E, Panakis, N, Pepperell, J C T, Howell, T, Stewart, S A, Penz, E, Jordan, N, Morley, A J, Zahan-Evans, N, Smith, S, Batchelor, T J P, Marchbank, A, Bishop, L, Ionescu, A A, Bayne, M, Cooper, S, Kerry, A L, Jenkins, P, Toy, E, Vigneswaran, V, Gildersleve, J, Ahmed, M, McDonald, F, Button, M, Lewanski, C, Comins, C, Dakshinamoorthy, M, Lee, Y C G, Rahman, N M & Maskell, N A 2016, ' Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART) : a multicentre, open-label, phase 3, randomised controlled trial ' The Lancet Oncology, vol 17, no. 8, pp. 1094-1104 . DOI: 10.1016/S1470-2045(16)30095-X
Clive, A O, Taylor, H, Dobson, L, Wilson, P, de Winton, E, Panakis, N, Pepperell, J C T, Howell, T, Stewart, S A, Penz, E, Jordan, N, Morley, A J, Zahan-Evans, N, Smith, S, Batchelor, T J P, Marchbank, A, Bishop, L, Ionescu, A A, Bayne, M, Cooper, S, Kerry, A L, Jenkins, P, Toy, E, Vigneswaran, V, Gildersleve, J, Ahmed, M, McDonald, F, Button, M, Lewanski, C, Comins, C, Dakshinamoorthy, M, Lee, Y C G, Rahman, N M & Maskell, N A 2016, ' Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART) : a multicentre, open-label, phase 3, randomised controlled trial ', Lancet Oncology, vol. 17, no. 8, pp. 1094-1104 . https://doi.org/10.1016/S1470-2045(16)30095-X

BackgroundThe use of prophylactic radiotherapy to prevent procedure-tract metastases (PTMs) in malignant pleural mesothelioma remains controversial, and clinical practice varies worldwide. We aimed to compare prophylactic radiotherapy with deferred r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bb10a2e1e402c1e5138b34e6a75fd4
https://doi.org/10.1016/s1470-2045(16)30095-x