Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Emma De Pater"'
Autor:
Cansu Koyunlar, Juncal Fernandez-Orth, Julia Weiss, Emanuele Gioacchino, HansDe Looper, Geoffrey Andrieux, Mariette Ter Borg, Baris Yigit, Joke Zink, Remco Hoogenboezem, Irene Gonzalez-Mendez, Eric Bindels, Mathijs Sanders, Ivo Touw, Miriam Erlacher, Emma De Pater
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100055- (2023)
Externí odkaz:
https://doaj.org/article/0194ceebb7504080841b12707daeaa21
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The correct maintenance and differentiation of hematopoietic stem cells (HSC) in bone marrow is vital for the maintenance and operation of the human blood system. GATA2 plays a critical role in the maintenance of HSCs and the specification of HSCs in
Externí odkaz:
https://doaj.org/article/07dfc3c98ca747a7af51e22802af1e1d
Autor:
Wei Zhang, Emanuele Gioacchino, Cansu Koyunlar, Joke Zink, Hans de Looper, Kirsten J. Gussinklo, Remco Hoogenboezem, Dennis Bosch, Eric Bindels, Ivo P. Touw, Emma de Pater
Publikováno v:
HemaSphere, Vol 7, p e94325dc (2023)
Externí odkaz:
https://doaj.org/article/30747f125c114725a39d2c81bfa3fc96
Autor:
Quincy Hofsink, Sabine Haggenburg, Birgit I. Lissenberg-Witte, Annoek E.C. Broers, Jaap A. van Doesum, Rob S. van Binnendijk, Gerco den Hartog, Michel S. Bhoekhan, Nienke J.E. Haverkate, Johan van Meerloo, Judith A. Burger, Joey H. Bouhuijs, Gaby P. Smits, Dorine Wouters, Ester M.M. van Leeuwen, Hetty J. Bontkes, Neeltje A. Kootstra, Sandra Vogels-Nooijen, Nynke Rots, Josine van Beek, Mirjam H.M. Heemskerk, Kazimierz Groen, Tom van Meerten, Pim G.N.J. Mutsaers, Marit J. van Gils, Abraham Goorhuis, Caroline E. Rutten, Mette D. Hazenberg, Inger S. Nijhof, Iris M.J. Kant, Thecla Graas, Belle Toussaint, Sterre de Jong, Shahan Darwesh, Sandjiv S. Mahes, Dora Kamminga, Matthijs Koelewijn, Gino Faber, Guus Beaumont, Marije D. Engel, R. Cheyenne N. Pierie, Suzanne R. Janssen, Edith van Dijkman, Jarom Heijmans, Yara Y. Witte, Rogers A. Nahui Palomino, Said Z. Omar, Sonja Zweegman, Arnon P. Kater, Caya van den Vegt, Ilonka Arends-Halbesma, Emma de Pater, Margriet J. Dijkstra, Nynke Y. Rots, Esther Siteur-van Rijnstra, Dennis M. de Rooij, Rogier W. Sanders, Meliawati Poniman, Wouter Olijhoek, Jacqueline van Rijswijk, Tim Beaumont, Lusia Çetinel, Louis Schellekens, Yvonne M. den Hartogh, Jacqueline Cloos, Suzanne S. Weijers, Saïda Tonouh-Aajoud, Selime Avci, Elianne Roelandse-Koop, Willem A. Dik
Publikováno v:
EClinicalMedicine, Vol 61, Iss , Pp 102040- (2023)
Summary: Background: Patients with haematological malignancies have impaired antibody responses to SARS-CoV-2 vaccination. We aimed to investigate whether a fourth mRNA COVID-19 vaccination improved antibody quantity and quality. Methods: In this coh
Externí odkaz:
https://doaj.org/article/b6705aeb989e44eeb7ee10f048616947
Autor:
Cansu Koyunlar, Emma de Pater
Publikováno v:
Frontiers in Genome Editing, Vol 2 (2020)
Inherited bone marrow failure syndromes (IBMFS) are monogenetic disorders that result in a reduction of mature blood cell formation and predisposition to leukemia. In children with myeloid leukemia the gene most often mutated is Gata binding protein
Externí odkaz:
https://doaj.org/article/443d5b4906a54d34bf5c987d26cba879
Autor:
Laura E Kuil, Nynke Oosterhof, Giuliano Ferrero, Tereza Mikulášová, Martina Hason, Jordy Dekker, Mireia Rovira, Herma C van der Linde, Paulina MH van Strien, Emma de Pater, Gerben Schaaf, Erik MJ Bindels, Valerie Wittamer, Tjakko J van Ham
Publikováno v:
eLife, Vol 9 (2020)
Macrophages derive from multiple sources of hematopoietic progenitors. Most macrophages require colony-stimulating factor 1 receptor (CSF1R), but some macrophages persist in the absence of CSF1R. Here, we analyzed mpeg1:GFP–expressing macrophages i
Externí odkaz:
https://doaj.org/article/ab98d27251c647b7b6ce1d7183bfc961
Autor:
Emma de Pater, Eirini Trompouki
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
Hematopoiesis is an optimal system for studying stem cell maintenance and lineage differentiation under physiological and pathological conditions. In vertebrate organisms, billions of differentiated hematopoietic cells need to be continuously produce
Externí odkaz:
https://doaj.org/article/6102f00d36664842ad3b4fc5decdea9f
Autor:
Parisa Imanirad, Parham Solaimani Kartalaei, Mihaela Crisan, Chris Vink, Tomoko Yamada-Inagawa, Emma de Pater, Dorota Kurek, Polynikis Kaimakis, Reiner van der Linden, Nancy Speck, Elaine Dzierzak
Publikováno v:
Stem Cell Research, Vol 12, Iss 1, Pp 24-35 (2014)
Hypoxia affects many physiologic processes during early stages of mammalian ontogeny, particularly placental and vascular development. In the adult, the hypoxic bone marrow microenvironment plays a role in regulating hematopoietic stem cell (HSC) fun
Externí odkaz:
https://doaj.org/article/3b6e7bf3519242d9815859da8e3e92e3
Autor:
Federico Tessadori, Jan Hendrik van Weerd, Silja B Burkhard, Arie O Verkerk, Emma de Pater, Bastiaan J Boukens, Aryan Vink, Vincent M Christoffels, Jeroen Bakkers
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47644 (2012)
In the mammalian heart a conduction system of nodes and conducting cells generates and transduces the electrical signals evoking myocardial contractions. Specialized pacemaker cells initiating and controlling cardiac contraction rhythmicity are local
Externí odkaz:
https://doaj.org/article/140dc362c5174df0958a27bc64963c64
Autor:
Cansu Koyunlar, Emanuele Gioacchino, Disha Vadgama, Hans de Looper, Joke Zink, Mariette N. D. ter Borg, Remco Hoogenboezem, Marije Havermans, Mathijs A. Sanders, Eric Bindels, Elaine Dzierzak, Ivo P. Touw, Emma de Pater
Publikováno v:
Blood advances, 7(10), 2082-2093. American Society of Hematology
The first hematopoietic stem cells (HSCs) are formed through endothelial-to-hematopoietic transition (EHT) during embryonic development. The transcription factor GATA2 is a crucial regulator of EHT and HSC function throughout life. Because patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3652163368a1dc54e4934546e737a66e
https://pure.eur.nl/en/publications/2abc2b14-76c7-4053-a73d-bbc731786991
https://pure.eur.nl/en/publications/2abc2b14-76c7-4053-a73d-bbc731786991