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pro vyhledávání: '"Emma Darios"'
Publikováno v:
Am J Physiol Heart Circ Physiol
Perivascular adipose tissue (PVAT) is increasingly recognized as an essential layer of the functional vasculature, being responsible for producing vasoactive substances and assisting arterial stress relaxation. Here, we test the hypothesis that PVAT
Publikováno v:
Hypertension. 70
Activation of the sympathetic nervous system, and the subsequent release of the neurotransmitter norepinephrine (NE), contracts blood vessels and increases blood pressure, a mechanism altered in obesity-related hypertension. Perivascular adipose tiss
Autor:
Emma Darios, Stephanie W Watts
Publikováno v:
Hypertension. 66
The adipokine chemerin causes contraction of isolated arteries and is implicated in blood pressure regulation, especially in the obese population that have elevated levels of circulating chemerin. Because chemerin is expressed in the perivascular adi
Publikováno v:
Hypertension. 66
In the vasculature, the adipokine chemerin is present in perivascular adipose tissue and causes arterial contraction through activation of the heptahelical receptor ChemR23. We presently test the hypothesis that ChemR23 is linked to procontractile si
Publikováno v:
Hypertension. 64
Serotonin (5-HT, 5-hydroxytryptamine) reduces blood pressure of the conscious rat when administered chronically (one week). 5-HT does not directly relax isolated arteries, and microsphere experiments in 5-HT-infused rats suggested that 5-HT increased