Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Emma D Flood"'
Autor:
Janice M. Thompson, Will Tragge, Emma D. Flood, Stefan Schulz, Erika Lisabeth, Stephanie W. Watts
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology.
Our laboratory has a vested interest in measuring the location and expression of the 5-hydroxytryptamine (5-HT, serotonin) 7 (5-HT7) receptor in the rat. Determining tissue-specific receptor expression would aid in validating understood and potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9269951bd7d122d1a5140e48fdef8aaa
https://doi.org/10.1007/s00210-023-02482-w
https://doi.org/10.1007/s00210-023-02482-w
Autor:
Emma A Wabel, Alexis Orr, Emma D Flood, Janice Thompson, Hannah Garver, Adam E Mullick, Gregory D Fink, Stephanie W Watts
Publikováno v:
Hypertension. 79
Evidence supports that Antisense oligonucleotides (ASO) against the adipokine chemerin reduce the blood pressure of the normal male Sprague Dawley rat and, to a greater magnitude, the hypertensive Dahl SS rat fed a high fat diet. In the Dahl SS rat,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b59b9a5e339e249f6e1f19e97fee0a1
https://doi.org/10.1161/hyp.79.suppl_1.p003
https://doi.org/10.1161/hyp.79.suppl_1.p003
Publikováno v:
Hypertension. 79
Perivascular adipose tissue (PVAT) modifies vascular function due to its capacity to synthesize vasoactive products and its mechanical properties. During cardiovascular diseases (CVD), changes in adipocyte populations affect PVAT function. In obesity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b202c2dcd3a1af070a541f04b165145
https://doi.org/10.1161/hyp.79.suppl_1.p057
https://doi.org/10.1161/hyp.79.suppl_1.p057
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
In health, PVAT secretes anti-contractile factors that relax the underlying artery. PVAT’s contributions to vascular function include more than production of vasoactive substances. We hypothesized that PVAT benefits the artery by assisting the func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16562a5a53b48cf6eb0e237a4f86a3ae
http://link.springer.com/article/10.1038/s41598-020-58368-x
http://link.springer.com/article/10.1038/s41598-020-58368-x
Publikováno v:
Pharmacol Res
The vasculature constantly experiences distension/pressure exerted by blood flow and responds to maintain homeostasis. We hypothesized that activation of the stretch sensitive, non-selective cation channel Piezo1 would directly increase vascular cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18d62716482fdcbc6b055041fd47bcd
https://pubmed.ncbi.nlm.nih.gov/34818570
https://pubmed.ncbi.nlm.nih.gov/34818570
Autor:
Emma D Flood, Miguel Leonardo Chirivi Gonzales, Janice M. Thompson, G.A. Contreras, Stephanie W. Watts, Cristian Javier Rendon Mora
Publikováno v:
Hypertension. 78
During hypertension, vascular remodeling allows the blood vessel to withstand high blood pressure (BP). This process is well characterized in the media and intima layers of the vessel. In the perivascular adipose tissue (PVAT) there is evidence for f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d65e79bf584741cf361ccbe51be258ff
https://doi.org/10.1161/hyp.78.suppl_1.p186
https://doi.org/10.1161/hyp.78.suppl_1.p186
Publikováno v:
Hypertension. 78
PVAT is increasingly recognized as an essential layer of the functional vasculature, producing vasoactive substances and assisting arterial stress relaxation. We test the hypothesis that PVAT reduces arterial stiffness. Our model was the thoracic aor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93908755d07b9ee74288ff9749aaa572
https://doi.org/10.1161/hyp.78.suppl_1.mp18
https://doi.org/10.1161/hyp.78.suppl_1.mp18
Autor:
Emma D Flood, Stephanie W. Watts, G. Andres Contreras, Yongliang Yang, Hannah Garver, Sudin Bhattacharya, Gregory D. Fink
Publikováno v:
Am J Physiol Heart Circ Physiol
Perivascular adipose tissue (PVAT) modifies the contractile function of the vessel it surrounds (outside-in signaling). Little work points to the vessel actively affecting its surrounding PVAT. We hypothesized that inside-out arterial signaling to PV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c7e88c6ea85c0f167a283534025999
https://pubmed.ncbi.nlm.nih.gov/33006918
https://pubmed.ncbi.nlm.nih.gov/33006918
Publikováno v:
Hypertension. 76
The vasculature constantly experiences distension/pressure exerted by the blood and responds accordingly to maintain homeostasis. Perivascular adipose tissue (PVAT) is gaining support as a formal blood vessel layer and also experiences these changes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1deaea1cb719e7cc0fd5f92843d07835
https://doi.org/10.1161/hyp.76.suppl_1.p061
https://doi.org/10.1161/hyp.76.suppl_1.p061
Autor:
Emma D Flood, G. Andres Contreras, Cristian Javier Rendon Mora, Stephanie W. Watts, Janice M. Thompson
Publikováno v:
Hypertension. 76
In adipogenesis, perivascular adipose tissue (PVAT) preadipocytes turn into adipocytes. In non-PVAT preadipocytes, mechanical forces affect the commitment and lipogenic stages of adipogenesis. The mechanism may involve PIEZO1, a mechanosensor, that b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80f279bbafe726d3dced3cb1764be6ed
https://doi.org/10.1161/hyp.76.suppl_1.p067
https://doi.org/10.1161/hyp.76.suppl_1.p067