Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Emma C. Troisi"'
Autor:
Rachael G. Aubin, Emma C. Troisi, Javier Montelongo, Adam N. Alghalith, Maclean P. Nasrallah, Mariarita Santi, Pablo G. Camara
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The molecular mechanisms underlying ependymoma tumorigenesis remain poorly understood. Here, single cell analysis of posterior fossa primary tumours and distal metastases highlights the role of pro-inflammatory cytokines in promoting epithelial-to-me
Externí odkaz:
https://doaj.org/article/5813a87138be474398527991ba01b4e8
Autor:
Xiaofeng Wang, Su Wang, Emma C. Troisi, Thomas P. Howard, Jeffrey R. Haswell, Bennett K. Wolf, William H. Hawk, Pilar Ramos, Elaine M. Oberlick, Evgeni P. Tzvetkov, Aaron Ross, Francisca Vazquez, William C. Hahn, Peter J. Park, Charles W. M. Roberts
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Mutations of the SWI/SNF chromatin-remodeling complex member SMARCB1 can cause malignant rhaboid tumors. Here the authors report a BRD9-containing SWI/SNF subcomplex that lacks SMARCB1 and its requirement for the survival of rhaboid tumors.
Externí odkaz:
https://doaj.org/article/4b69173f717e4efcb19c2a38dcdb58fd
Autor:
Xiaofeng Wang, Su Wang, Emma C. Troisi, Thomas P. Howard, Jeffrey R. Haswell, Bennett K. Wolf, William H. Hawk, Pilar Ramos, Elaine M. Oberlick, Evgeni P. Tzvetkov, Aaron Ross, Francisca Vazquez, William C. Hahn, Peter J. Park, Charles W. M. Roberts
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/18b73f82f0e648d5964d49583e0eeb78
Autor:
Steven Woodhouse, Rachael G. Aubin, Pablo G. Camara, Zhen Miao, Emma C. Troisi, Kiya W. Govek
Publikováno v:
Science Advances
Mapping single-cell RNA-seq data onto IHC images enables the annotation of cell populations at high phenotypic resolution.
Highly multiplexed immunohistochemistry (mIHC) enables the staining and quantification of dozens of antigens in a tissue s
Highly multiplexed immunohistochemistry (mIHC) enables the staining and quantification of dozens of antigens in a tissue s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fafa2713bcc878a1c127728f24caf09
http://europepmc.org/articles/PMC7935366
http://europepmc.org/articles/PMC7935366
Cell Ecosystem and Signaling Pathways of Primary and Metastatic Pediatric Posterior Fossa Ependymoma
Autor:
Emma C. Troisi, MacLean Nasrallah, Adam N. Alghalith, Pablo G. Camara, Rachael G. Aubin, Mariarita Santi
Pediatric ependymoma is a devastating brain cancer marked by its relapsing pattern and lack of effective chemotherapies. This shortage of treatments is partially due to limited knowledge about ependymoma tumorigenic mechanisms. Although there is evid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d97701ae00732732bd0087dbadd56bda
https://doi.org/10.1101/2020.08.10.244483
https://doi.org/10.1101/2020.08.10.244483
Cell Ecosystem and Signaling Pathways of Primary and Metastatic Pediatric Posterior Fossa Ependymoma
Autor:
Pablo G. Camara, Mariarita Santi, Rachael G. Aubin, MacLean Nasrallah, Adam N. Alghalith, Emma C. Troisi
Publikováno v:
SSRN Electronic Journal.
Pediatric ependymoma is a devastating brain cancer marked by its relapsing pattern and lack of effective chemotherapies. This shortage of treatments is partially due to limited knowledge about ependymoma tumorigenic mechanisms. Although there is evid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e1bc4e1aa8550613acbb3edcd68fa0
https://doi.org/10.2139/ssrn.3686061
https://doi.org/10.2139/ssrn.3686061
Autor:
Rachael G. Aubin, Adam N. Alghalith, MacLean Nasrallah, Emma C. Troisi, Mariarita Santi, Pablo G. Camara
Publikováno v:
Neuro-Oncology
Childhood ependymoma is a cancer of the central nervous system with a chronic relapsing pattern. In children, 90% of ependymal tumors occur intracranially where prognosis is grim. Standard care for this disease includes surgical resection followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81071e9911240e7a497d311f5d161428
https://doi.org/10.1093/neuonc/noab090.056
https://doi.org/10.1093/neuonc/noab090.056
Autor:
Jakub Mieczkowski, Yotam Drier, Su Wang, Scott L. Pomeroy, Burak H. Alver, Bradley E. Bernstein, Charles W. M. Roberts, Ryan S. Lee, Shawn M. Gillespie, Peter J. Park, Michael Y. Tolstorukov, Xiaofeng Wang, Tenley C. Archer, Jaclyn A. Biegel, Jeffrey R. Haswell, Evgeni P. Tzvetkov, Emma C. Troisi, Jennifer Wu
Publikováno v:
Nature genetics
SMARCB1 (also known as SNF5, INI1, and BAF47), a core subunit of the SWI/SNF (BAF) chromatin-remodeling complex, is inactivated in nearly all pediatric rhabdoid tumors. These aggressive cancers are among the most genomically stable, suggesting an epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc2433191d995a148f8b4f474e15267
http://europepmc.org/articles/PMC5285474
http://europepmc.org/articles/PMC5285474
Histology provides a unique window into the cellular and molecular architecture of tissues and is a critical component of biomedical research and clinical practice. Highly-multiplexed immunohistochemistry 1-6 (mIHC) enables the routine staining and q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f64d3a8dfd39de190f0cb2a0738925
https://doi.org/10.1101/672501
https://doi.org/10.1101/672501
Autor:
William H. Hawk, Evgeni P. Tzvetkov, Thomas P. Howard, Jeffrey R. Haswell, Emma C. Troisi, Pilar Ramos, Elaine M. Oberlick, Peter J. Park, Aaron Ross, Charles W. M. Roberts, Su Wang, William C. Hahn, Francisca Vazquez, Bennett K. Wolf, Xiaofeng Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Bromodomain-containing protein 9 (BRD9) is a recently identified subunit of SWI/SNF(BAF) chromatin remodeling complexes, yet its function is poorly understood. Here, using a genome-wide CRISPR-Cas9 screen, we show that BRD9 is a specific vulnerabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbbb6b953eb21a5ee628eebea57d83f
http://europepmc.org/articles/PMC6479050
http://europepmc.org/articles/PMC6479050