Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Emma C. Reilly"'
Autor:
Emma C. Reilly, Mike Sportiello, Kris Lambert Emo, Andrea M. Amitrano, Rakshanda Jha, Ashwin B. R. Kumar, Nathan G. Laniewski, Hongmei Yang, Minsoo Kim, David J. Topham
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CD8 T cell memory offers critical antiviral protection, even in the absence of neutralizing antibodies. The paradigm is that CD8 T cell memory within the lung tissue consists of a mix of circulating TEM cells and non-circulating TRM cells. However, b
Externí odkaz:
https://doaj.org/article/7b93e7b976014f638ba3b9ee4445492d
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 537-548.e5 (2019)
Summary: The role of non-classical T cells during viral infection remains poorly understood. Using the well-established murine model of CMV infection (MCMV) and mice deficient in MHC class Ia molecules, we found that non-classical CD8+ T cells robust
Externí odkaz:
https://doaj.org/article/b1db322df0134b0e8163917f59c0ece4
Autor:
David J. Topham, Emma C. Reilly
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Tissue-resident memory CD8+ T cells are an important first line of defense from infection in peripheral non-lymphoid tissues, such as the mucosal tissues of the respiratory, digestive, and urogenital tracts. This memory T cell subset is established l
Externí odkaz:
https://doaj.org/article/969a46fd37e74d6faf954db08a269799
Autor:
S. M. Shahjahan Miah, Chathuraka T. Jayasuriya, Alexander I. Salter, Emma C. Reilly, Céline Fugere, Wentian Yang, Qian Chen, Laurent Brossay
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The ubiquitously expressed tyrosine phosphatase Src homology region 2 domain-containing phosphatase-2 (SHP-2, encoded by Ptpn11) is required for constitutive cellular processes including proliferation, differentiation, and the regulation of immune re
Externí odkaz:
https://doaj.org/article/50a394ed81284e4b95a06f6f2878920e
Autor:
Laura Rodriguez, Pilar Blanco-Lobo, Emma C. Reilly, Tatsuya Maehigashi, Aitor Nogales, Andrew Smith, David J. Topham, Stephen Dewhurst, Baek Kim, Luis Martínez-Sobrido
Publikováno v:
Viruses, Vol 11, Iss 10, p 928 (2019)
Influenza viruses cause annual, seasonal infection across the globe. Vaccination represents the most effective strategy to prevent such infections and/or to reduce viral disease. Two major types of influenza vaccines are approved for human use: inact
Externí odkaz:
https://doaj.org/article/787540cdb05e40fe98cd59232a5933a8
Publikováno v:
Pathogens, Vol 8, Iss 4, p 196 (2019)
Tissue resident memory (TRM) CD8 T cells comprise a memory population that forms in peripheral, non-lymphoid tissues after an infection that does not recirculate into the bloodstream or other tissues. TRM cells often recognize conserved peptide epito
Externí odkaz:
https://doaj.org/article/99e3f1068f694fad88c9bb801895ecb6
Autor:
Mike Sportiello, Alexis Poindexter, Emma C. Reilly, Adam Geber, Kris Lambert Emo, Taylor N. Jones, David J. Topham
Tissue-resident memory CD8 T cells (TRM) principally reside in peripheral non-lymphoid tissues such as lung and skin and confer protection against a variety of illnesses ranging from infections to cancers. The functions of different memory CD8 T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ed2514ea040f2f9690addc89a43525
https://doi.org/10.1101/2022.09.21.508875
https://doi.org/10.1101/2022.09.21.508875
Autor:
Mike Sportiello, Adam Geber, Rohith Palli, A Karim Embong, Nathan G. Laniewski, Emma C. Reilly, Kris Lambert Emo, David J. Topham
BackgroundMany tools exist to perform a rigorous pathway analysis, though traditional gene set enrichment analysis remains among the most common. While useful for many applications, one common situation where it is less so is the metabolic profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7108a660d8a5abfa95c138af974dc5b
https://doi.org/10.1101/2022.03.15.484417
https://doi.org/10.1101/2022.03.15.484417
Autor:
Natalio Garbi, Stav Kozlovski, Mike Sportiello, David J. Topham, Emma C. Reilly, Ronen Alon, Ashwin B. R. Kumar, Alexander Zarbock
Publikováno v:
Nature Reviews. Immunology
Nature Reviews Immunology
Nature Reviews Immunology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes underlying the versatile clinical manifestations of COVID-19 is incomplete without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6beb264e7e292efb853227c5df32bf9
http://europepmc.org/articles/PMC7675406
http://europepmc.org/articles/PMC7675406
Autor:
David J. Topham, Emma C. Reilly, Patrick J. Buckley, Nicholas S. Reilly, Kris Lambert Emo, Francisco A. Chaves, Patrick W. Oakes, Ian Smith, Hongmei Yang
Publikováno v:
Proceedings of the National Academy of Sciences. 117:12306-12314
Tissue-resident memory CD8 T (T RM ) cells are a unique immune memory subset that develops and remains in peripheral tissues at the site of infection, providing future host resistance upon reexposure to that pathogen. In the pulmonary system, T RM ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00617ecdf390078df61cc93dda5bfd27
https://doi.org/10.1073/pnas.1915681117
https://doi.org/10.1073/pnas.1915681117