Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Emma C. Backlund"'
Autor:
Edoardo Dalla Nora, Barbara Cannon, Monia Manieri, Robert C. Noland, Antonio Vidal-Puig, Sam Virtue, Emma C. Backlund, Sarah L. Gray, Saverio Cinti, Ronald N. Cortright, Stephen O'Rahilly
Publikováno v:
Endocrinology. 147:5708-5714
Mice with a dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutation (P465L) unexpectedly had normal amounts of adipose tissue. Here, we investigate the adipose tissue of the PPARgamma P465L mouse in detail. Microscopic
Autor:
Emma C. Backlund, Valeria Golozoubova, Anders Jacobsson, Irina G. Shabalina, Kjetil Retterstøl, Petr Tvrdik, Mario R. Capecchi, Jan Erik Månsson, Rolf Westerberg
Publikováno v:
Journal of Biological Chemistry. 281:4958-4968
During the recruitment process of brown adipose tissue, the mRNA level of the fatty acyl chain elongase Elovl3 is elevated more than 200-fold in cold-stressed mice. We have obtained Elovl3-ablated mice and report here that, although cold-acclimated E
Autor:
Nils-Göran Larsson, Jan Nedergaard, Emma C. Backlund, Natasa Petrovic, Eric Dufour, Barbara Cannon, Rolf Wibom, José P. Silva, Irina G. Shabalina, Kjell Hultenby
Publikováno v:
The EMBO Journal. 24:4061-4070
We have created P1 artificial chromosome transgenic mice expressing the human mitochondrial superoxide dismutase 2 (SOD2) and thus generated mice with a physiologically controlled augmentation of SOD2 expression leading to increased SOD2 enzyme activ
Autor:
Sten G. E. Lindahl, Kerstin B. E. Ohlson, Emma C. Backlund, G. E. Bronnikov, Jan Nedergaard, Nina Mohell, Barbara Cannon, Irina G. Shabalina, Katarina Lennström
Publikováno v:
Biochemical Pharmacology. 68:463-477
Volatile anesthetics such as halothane efficiently inhibit nonshivering thermogenesis as well as the cellular manifestation of that phenomenon: norepinephrine-induced respiration in brown adipocytes. To identify the molecular site(s) of action of suc
Autor:
Emma C. Backlund, Irina G. Shabalina, Jan Nedergaard, Barbara Cannon, Helena M. Feldmann, Valeria Golozoubova
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777
Autor:
Peter Arner, Maria Kaaman, Barbara Cannon, Emma C. Backlund, Mikael Rydén, Lennart Blomqvist, Jan Nedergaard, Ingrid Dahlman, Elisabet Arvidsson Nordström
Publikováno v:
Diabetes. 54(6)
Elevated circulating fatty acid concentration is a hallmark of insulin resistance and is at least in part attributed to the action of adipose tissue-derived tumor necrosis factor-alpha (TNF-alpha) on lipolysis. Cell death-inducing DFFA (DNA fragmenta
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. (7-8):642-650
In the present investigation, we have utilized the availability of UCP1(-/-) mice to examine a wide range of previously proposed lipid activators of Uncoupling Protein 1 (UCP1) in its native environment, i.e. in the brown-fat cells. A non-metabolizab