Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Emma C Reilly"'
Autor:
Landon G Vom Steeg, Santosh Dhakal, Yishak A Woldetsadik, Han-Sol Park, Kathleen R Mulka, Emma C Reilly, David J Topham, Sabra L Klein
Publikováno v:
PLoS Pathogens, Vol 16, Iss 7, p e1008506 (2020)
Circulating androgens can modulate immune cell activity, but the impact of androgens on viral pathogenesis remains unclear. Previous data demonstrate that testosterone reduces the severity of influenza A virus (IAV) infection in male mice by mitigati
Externí odkaz:
https://doaj.org/article/89744cb61790481ab2a3a0f23f56794d
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0227157 (2020)
In mice, experimental influenza virus infection stimulates CD8 T cell infiltration of the airways. Virus is cleared by day 9, and between days 8 and 9 there is an abrupt change in CD8 T cell motility behavior transitioning from low velocity and high
Externí odkaz:
https://doaj.org/article/57e11a3c8a5048f39e38e21fe258f204
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164247 (2016)
After disease resolution, a small subset of influenza specific CD8+ T cells can remain in the airways of the lung as a tissue resident memory population (TRM). These cells are critical for protection from subsequent infections with heterosubtypic inf
Externí odkaz:
https://doaj.org/article/96172128b25645eda5ce06fb77ab1484
Autor:
Emma C Reilly, Elizabeth A Thompson, Sandrine Aspeslagh, Jack R Wands, Dirk Elewaut, Laurent Brossay
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37991 (2012)
α-Galactosylceramide (α-GalCer) is the prototypical lipid ligand for invariant NKT cells. Recent studies have proposed that α-GalCer is an effective adjuvant in vaccination against a range of immune challenges, however its mechanism of action has
Externí odkaz:
https://doaj.org/article/0352e36d096e453ab67ddb4ab6034b8b
Publikováno v:
PLoS Pathogens, Vol 7, Iss 1, p e1001254 (2011)
Natural killer (NK) cells and CD8(+) T cells play vital roles in containing and eliminating systemic cytomegalovirus (CMV). However, CMV has a tropism for the salivary gland acinar epithelial cells and persists in this organ for several weeks after p
Externí odkaz:
https://doaj.org/article/0ced4f1a07e442a5a2f7d1cc5952d930
Autor:
Mike Sportiello, Alexis Poindexter, Emma C. Reilly, Adam Geber, Kris Lambert Emo, Taylor N. Jones, David J. Topham
Tissue-resident memory CD8 T cells (TRM) principally reside in peripheral non-lymphoid tissues such as lung and skin and confer protection against a variety of illnesses ranging from infections to cancers. The functions of different memory CD8 T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82ed2514ea040f2f9690addc89a43525
https://doi.org/10.1101/2022.09.21.508875
https://doi.org/10.1101/2022.09.21.508875
Autor:
Mike Sportiello, Adam Geber, Rohith Palli, A Karim Embong, Nathan G. Laniewski, Emma C. Reilly, Kris Lambert Emo, David J. Topham
BackgroundMany tools exist to perform a rigorous pathway analysis, though traditional gene set enrichment analysis remains among the most common. While useful for many applications, one common situation where it is less so is the metabolic profiling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7108a660d8a5abfa95c138af974dc5b
https://doi.org/10.1101/2022.03.15.484417
https://doi.org/10.1101/2022.03.15.484417
Autor:
Natalio Garbi, Stav Kozlovski, Mike Sportiello, David J. Topham, Emma C. Reilly, Ronen Alon, Ashwin B. R. Kumar, Alexander Zarbock
Publikováno v:
Nature Reviews. Immunology
Nature Reviews Immunology
Nature Reviews Immunology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes underlying the versatile clinical manifestations of COVID-19 is incomplete without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6beb264e7e292efb853227c5df32bf9
http://europepmc.org/articles/PMC7675406
http://europepmc.org/articles/PMC7675406
Autor:
David J. Topham, Emma C. Reilly, Patrick J. Buckley, Nicholas S. Reilly, Kris Lambert Emo, Francisco A. Chaves, Patrick W. Oakes, Ian Smith, Hongmei Yang
Publikováno v:
Proceedings of the National Academy of Sciences. 117:12306-12314
Tissue-resident memory CD8 T (T RM ) cells are a unique immune memory subset that develops and remains in peripheral tissues at the site of infection, providing future host resistance upon reexposure to that pathogen. In the pulmonary system, T RM ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00617ecdf390078df61cc93dda5bfd27
https://doi.org/10.1073/pnas.1915681117
https://doi.org/10.1073/pnas.1915681117
Autor:
Emma C. Reilly, Mike Sportiello, Kris Lambert Emo, Andrea M. Amitrano, Rakshanda Jha, Ashwin B. R. Kumar, Nathan G. Laniewski, Hongmei Yang, Minsoo Kim, David J. Topham
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
CD8 T cell memory offers critical antiviral protection, even in the absence of neutralizing antibodies. The paradigm is that CD8 T cell memory within the lung tissue consists of a mix of circulating TEMcells and non-circulating TRMcells. However, bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb91d501a3c06cc8f384d01b51576cf7
https://doi.org/10.1101/2021.07.30.454373
https://doi.org/10.1101/2021.07.30.454373