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pro vyhledávání: '"Emma C Buchele"'
Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44.
Autor:
Deborah Wessels, Daniel F Lusche, Edward Voss, Spencer Kuhl, Emma C Buchele, Michael R Klemme, Kanoe B Russell, Joseph Ambrose, Benjamin A Soll, Aaron Bossler, Mohammed Milhem, Charles Goldman, David R Soll
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173400 (2017)
Using unique computer-assisted 3D reconstruction software, it was previously demonstrated that tumorigenic cell lines derived from breast tumors, when seeded in a 3D Matrigel model, grew as clonal aggregates which, after approximately 100 hours, unde
Externí odkaz:
https://doaj.org/article/6d777a850b8641f88679938c708d805f
Autor:
David R. Soll, Emma C. Buchele, Kanoe B. Russell, Michele Vitolo, Deborah Wessels, Daniel F. Lusche, Michael R. Klemme, Benjamin A. Soll
Publikováno v:
Oncotarget. 9:21100-21121
One possible approach to normalize mutant cells that are metastatic and tumorigenic, is to upregulate a functionally similar homolog of the mutated gene. Here we have explored this hypothesis by generating an overexpressor of TPTE2 (TPIP), a homolog
Autor:
Daniel F, Lusche, Emma C, Buchele, Kanoe B, Russell, Benjamin A, Soll, Michele I, Vitolo, Michael R, Klemme, Deborah J, Wessels, David R, Soll
Publikováno v:
Oncotarget
One possible approach to normalize mutant cells that are metastatic and tumorigenic, is to upregulate a functionally similar homolog of the mutated gene. Here we have explored this hypothesis by generating an overexpressor of TPTE2 (TPIP), a homolog